Ciência sem Fronteiras (Science Without Borders) PhD Project Template: PI name & contact details: Catherine Adley Department Microbiology Laboratory Department of Chemical and Environmental Sciences University of Limerick Limerick Ireland Has project been agreed with head (or nominee) of proposed registration school? Research Centre / group affiliation: Environment for Health Research Group Research group / centre website: Centre for Environmental Science http://www3.ul.ie/~cer/ PI website / link to CV: Web: www.ul.ie/~ces/CatherineAdley Brief summary of PI research / research group / centre activity (2 or 3 lines max): Mobility of antibiotic resistance genes in the environment: Monitoring, surveillance, cross contamination and hygiene control in particular of food borne pathogens Salmonella and Bacillus cereus Title & brief description of PhD project (suitable for publication on web): Biocides have been in use for hundreds of years for antisepsis, disinfection and preservation. Despite this widespread and ever increasing use most bacterial and fungal species remain susceptible to biocides. The dramatic increase and spread of resistance to antibiotics linked to reports of co- and cross-resistance between antibiotics and biocides raised speculations on potential hazard of biocide use. The overarching question which this project addresses: has the use of biocides contributed to the development and spread of significant antibiotic resistance in human pathogens in particular food borne pathogesn? Unique selling points of PhD project in UL: The candidate will have access to a well-equipped laboratories including: Microbiology suite: incubators, freezers, temperature controlled incubation rooms. Safety cabinets, standard and refrigerated centrifuges including Heraeus MegaFuge 40R and 16R; TypeII Containment facilities; Biocore x100 Molecular Biology suite: Standard personal PCR units; Roche Light Cycler 480II, nanodrop1000 Microscopy suite: AFM-JEOL JEM-2100F; SEM-Carry Scope JEOL JCM-5700; Hitachi SU-70; Laser Scanning Confocal Microscope Zeiss LSM 710 META; Spectroscopy suite: Raman Dilor XY Labram spectrometer equipped with an Olympus BX40; and RamanRXN2 Analyzer-785nm with a selection of probes. The university is located near an International airport at Shannon It will be possible to collaborate with Dr. Douglas McIntosh, Universidade Federal Rural do Rio de Janeiro, Departamento de Parasitologia Animal Name & contact details for project queries, if different from PI named above: As above Please indicate the graduates of which disciplines that should apply: Environmental science ; Biology; Microbiology; Biochemistry; Please indicate whether students can apply for: Sandwich programme only Full PhD programme only x Either of the above Ciência sem Fronteiras / Science Without Borders Priority Area: Please indicate the specific programme priority area under which the proposed PhD project fits- choose only one (tick box): Engineering and other technological areas Pure and Natural Sciences (e.g. mathematics, physics, chemistry) Health and Biomedical Sciences x Information and Communication Technologies (ICTs) Aerospace Pharmaceuticals Oil, Gas and Coal Renewable Energy Minerals Biotechnology x Nanotechnology and New Materials Technology of prevention and remediation of natural disasters Biodiversity and Bioprospection Marine Sciences Creative Industry New technologies in constructive engineering