Anatomy 32 Lecture Chapter 19 - Blood Vessels I. Overview A. Blood Vessel Structure B. Arteries C. Capillaries D. Veins E. Blood Pressure F. Principal Arteries of the Body G. Principal Veins of the Body H. Blood Vessel Disorders I. Differences in Fetal Circulation II. Blood Vessel Structure A. Blood leaving the heart passes through a ______ route in the body 1. Blood moves ______ from the heart to body tissues through __________ to arterioles to capillaries 2. Blood moves back to the heart from capillaries to venules to ________ B. The walls of arteries & veins are composed of three _____ (layers) 1. Tunica _________ (adventitia) - outermost layer, composed of loose fibrous CT; protects the blood vessle 2. Tunica _________ - middle layer, composed of smooth muscle and elastic fibers; muscle contraction = vaso_____________; muscle relaxation = vaso___________ 3. Tunica _________ (interna) - innermost layer, of endothelium and elastin (capillaries consist of endothelium only on a basement membrane) 4. The ________ is the central blood-filled space in the vessel. C. Some ______________ between arteries & veins: 1. Arteries have a _________ T. media and are rounder than veins in cross section 2. Veins are usually partially collapsed, and many have _______ that are absent in arteries D. Arteries - carry blood (usually oxygenated) ______ from the heart 1. Large _________ arteries (e.g.: aorta & major branches) have many _________ fibers, thus expand when BP rises as heart contracts, then recoil when the heart relaxes 2. _________ arteries are smaller arteries and are less elastic with a thicker layer of smooth ________ in relation to their diameters 3. ___________ are the smallest arteries with only 1-2 layers of smooth muscle over endothelium E. ______________ - narrowest of the blood vessels; the functional units of the circulatory system 1. Capillary walls are composed of just one layer of _____thelium in a basal lamina 2 2. It is across capillary walls that gases (___ & ____), nutrients, and wastes are exchanged with tissues 3. Blood flow from arteriole into a capillary bed is controlled by precapillary _____________ muscles 4. When sphincters close, blood from arterioles enters venules directly via thoroughfare ________ that form vascular ______ 5. Types of capillaries include a. _______________ capillaries are the most common; have endothelial cells with ________ junctions, found in muscles, lungs, & the CNS (e.g.: the blood brain barrier) b. _________ capillaries have wide intercellular pores, found in kidneys, and intestines; __________ capillaries found in bone marrow, liver, & spleen; allow large molecules to pass through F. ______ - vessels that carry blood from capillaries back __ the heart 1. BP is very low in veins & _________ due to their distance from the heart 2. Blood is returned to the heart largely via skeletal muscle _______: as skeletal muscles contract, they squeeze associated veins, pumping the blood toward the heart 3. One way venous _______ prevent blood backflow in veins G. _____________ - force exerted by the blood on inner vessel walls 1. BP is much _______ in arteries & arterioles than in capillaries, venules & veins 2. Arterial BP can be measured with a _______manometer and a stethoscope 3. Normal adult BP is about ___/___, where 120 mm Hg is the __________ pressure and 80 mm Hg is the _________ pressure 4. a. Systolic pressure is created by blood flow through arteries during ventricular ____________ (contraction) b. Diastolic pressure is a measurement of arterial pressure during ventricular ____________ (relaxation) c. The difference between the systolic & diastolic pressures is the ____________ pressure (usually about _____ mm Hg) ______________ is an elevated BP, dangerous because of the damage to heart and other vital organs caused by it III. Principal ____________ of the Body A. The ___________ arteries carry blood low in oxygen to the lungs to pick up oxygen. B. The _______ is the largest artery in the body, emerging from the left ventricle, then branching into arteries of the head, arms, trunk, and legs in the following manner C. Left & right _________ arteries emerge from the ascending aorta D. The ___________ has three major branches: the brachiocephalic trunk, left common carotid, & left subclavian arteries (______) 1. ______________ trunk - first branch, supplies blood to the shoulder, arms, and right side of head. This vessel branches into a. Right _________________ artery - extends to the right neck & head 3 b. Right ______________ artery - carries blood to the right shoulder & arm. D. Arteries of the Neck & Head 1. Left ________________ artery - both common carotid arteries are found on either side of the trachea and supply blood to the brain. They branch at the larynx into the: 2. a. ___________ carotid artery - enters the skull through the carotid canal to supply the eye orbit & cerebrum b. ___________ carotid artery, which branches to the thyroid, larynx, tongue (lingual), face, scalp, & chewing (maxillary) muscles _________ arteries branch off the subclavian arteries and also supply blood to the head, passing through the ______ transverse foramina and foramen magnum where they join to form the a. __________ artery, which branches to the cerebellum, pons, inner ear, temporal & occipital lobes, eventually forming the b. _________ arterial _______ (of Willis), which surrounds the pituitary gland & optic chiasma at the base of the brain; this circle unites the ant. & post. blood supplies from the internal _________ & ___________ arteries. E. Arteries of the Shoulder & Upper Extremity - major branches of the ____________ arteries include the 1. 2. ________ A. - continuation of subclavian in the axillary region 3. __________ & ______ arteries, which parallel their respective bones, then merge to form the 4. _________ arch, off which the ________ (for each digit)branch __________ A. - continuation of axillary through the brachial area; on the medial humerous, it is the most common site for determining _____. This artery branches into the F. Branches of the Descending _________ _________ 1. The thoracic aorta is a continuation of the aortic arch into the ________ cavity, superior to the diaphragm. Branches include: 2. 3. 4. 5. Pericardial arteries - to the heart ___________ 6. Superior __________ arteries - to the diaphragm Bronchial arteries - to the _______ Esophageal arteries - to the ___________ Posterior intercostal arteries - to the __________ muscles and thorax wall structures G. Branches of the Descending ___________ _________ 1. The abdominal aorta is the segment between the __________ & 4th ________ vertebrae, where it branches into the left & right common iliac arteries. From the diaphragm downward, major branches are 2. ______________ - arises just inferior to the diaphragm, divides into 3 arteries: a. b. __________ - to the spleen Left ___________ - to the stomach 4 c. Common __________ - to the liver 3. Superior ___________ artery - arises anteriorly inferior to the celiac trunk; supplies blood to much of the small & large ____________ 4. 5. 6. 7. _________ arteries (L. & R.) - supply kidneys with blood Suprarenal arteries (L. & R.) superior to __________, supply adrenal glands ____________ arteries (L. & R.) - supply blood to the gonads Inferior ______________ - last major branch of the abdominal aorta before the iliac bifurcation, supplies blood to the _______ & rectum 8. __________ arteries branch laterally off the length of the abdominal aorta to serve the muscles & spinal cord in the lumbar region H. Arteries of the _______ & Lower Extremities 1. The abdominal aorta divides into the L. & R. _______________ arteries, each of which divides into 2. External & Internal _________ arteries a. The _________ iliac branches to supply the __________ muscles and pelvic organs b. The _______ iliac passes out of the pelvic cavity & branches into the 1) ___________ artery, which branches into the 2) ________ femoral artery to the hamstrings 3) ___________ artery passes posterior to the knee, then divides into the 4) Anterior & Posterior ________ arteries, which supply blood to the leg & foot 5) The dorsalis _______ artery, near the medial malleolus, is often palpated after surgery to see if blood flow to the foot has resumed. IV. Principal ___________ of the Body A. Veins from the whole body (except lungs) converge into the superior & inferior _________, which empty into the R. atrium B. Veins may be superficial and deep 1. ____________ veins may be seen through the skin 2. _______ veins often parallel principal arteries of the same name C. ______________ veins return oxygenated blood from the lungs to the heart D. Veins Draining the Head & _______ 1. ________________ veins (L. & R.) on lateral sides of the ____; they drain blood from the scalp, face, and superficial neck, and empty into the 2. 3. L. & R. _____________ veins (posterior to the clavicles) 4. 5. ________________ veins (L. & R.), which merge to form the ________________ veins (L. & R.) drain blood from the brain, meninges, and deep face & neck; adjacent to common carotid arteries and vagus nerve, all 3 are surrounded by a _________ ________. Internal jugulars converge with the Superior _____________, which drains into the R. atrium 5 E. Veins of the Upper Extremities 1. 2. 3. 4. 5. 6. Toward the arm, the __________________ veins become the 1. 2. The superior ____________ also drains blood from the R. & L. ______________ veins, which branch to form the __________ (medial) & cephalic (lateral) veins; the axillary branches into the Basilic (medial) & _______ vein, which branches to form the ___________ & ulnar veins, which merge to form the palmar arch with digitals The _______ ________ vein courses diagonally across the inner elbow from the cephalic vein (lateral) to the basilic vein (medial). The median cubital is often the site of ________ withdrawal F. Veins of the __________ ___________ vein that extends superiorly along the posterior abdominal & thoracic walls on the _______ side of the vertebral column. Tributaries of the azygous include the 3. _____azygous veins, which form the major tributaries to the _____ of the vertebral column G. Veins of the Lower Extremities 1. Posterior & anterior _________ veins originate in the foot and pass upward behind the knee to form the 2. 3. 4. _____________ vein, above the knee this becomes the 5. 6. 7. 8. 9. Great ____________ vein (longest vein in the body), and then becomes the 1. 2. The inferior vena cava parallels the abdominal ________ 3. 4. 5. 6. 7. 4 paired _________ veins drain the posterior abdomen ________ vein, which continues up the thigh and receives blood from the ________ ________ vein near the groin. Above this point, the femoral vein receives the __________ _________ vein, which merges with the ___________________ vein to form the __________ _________ vein, left & right merge to form the Inferior ____________ H. Veins of the ____________ Region As the inferior vena cava ascends, it receives tributaries that correspond to adjacent arteries previously described. These tributaries include __________ veins - drain blood from the kidneys & ureters ____________ veins drain blood from the gonads Inferior __________ veins receive blood from the inferior diaphragm R. & L. _________ veins originate from the liver and join the inferior vena cava immediately below the diaphragm 6 8. Blood from the GI tract, pancreas, & spleen must pass through capillaries in the _______ via the hepatic portal system before passing to the vena cava I. Hepatic _______ System - consists of veins that drain blood from ___________ in the intestines, pancreas, spleen, stomach, and gall bladder, into liver capillaries (__________) & the R. & L. hepatic veins that drain the liver and empty into the vena cava 1. Absorbed products of digestion must first pass through the ________ to be processed before entering general circulation 2. The hepatic _________ vein receives blood from the digestive organs; it is formed by the union of the a. b. 4. Superior _____________ vein (from the small intestine) ____________ vein (from the spleen). The splenic vein has 3 tributaries: 1) Inferior ______________ - from the large intestine 2) ________________ vein - from the pancreas 3) __________________ (gastric) vein - from the stomach Note that the liver receives blood from ___ sources: a. b. The hepatic _______ supplies oxygen rich blood to the liver The hepatic ________ ______ transports nutrient rich blood from the digestive organs for processing V. Blood Vessel Disorders A. _______sclerosis (hardening of the arteries) - thickening and loss of elasticity of arterial walls B. ________sclerosis - most common type of arteriosclerosis; the arterial tunica intima thickens with atherosclerotic _________ that narrow and can eventually block the artery lumen, causing 1. 2. __________ (CVA) if an artery to the brain is blocked Myocardial _____________ if a coronary artery is blocked C. An ___________ is a bulge in an artery or vein that puts the vessel at risk of rupturing 1. May result from a congenital defect, _________________, or arteriosclerosis 2. Usually occurs in the abdominal aorta and arteries of the _____ & kidneys VI. Differences in _____________ Circulation A. Fetal Vessels to & from the Placenta 1. The __________ is a shared structure of the fetus and mother across which nutrients & oxygen diffuse from mother to child and wastes & CO2 diffuse from fetus to mother 2. Paired _________________ branch from internal iliac arteries and carry blood to the placenta to pick up oxygen & nutrients 3. A single ______________ returns the blood to the fetus’ hepatic portal vein or through the _______________, where it proceeds into the hepatic veins, inferior vena cava, and right atrium. 4. At birth, the umbilical vein becomes the ligamentum _______, whereas the ductus venosus becomes the ligamentum _______ 7 B. Shunts Away from the ______________ Circuit 1. _________________ - hole (valve) in the interatrial septum that diverts some blood 2. from the R. atrium to the L. atrium; this closes at birth to become the _________ ___________ __________ arteriosus - short artery that diverts blood from the pulmonary trunk to the aorta; closes at birth to become the _____________ arteriosum