Study Guide for Test Name Inheritance and Genetics Honors Biology Terms and Concepts Reproduction Sexual Reproduction Asexual Reproduction DNA Gene Genotype Phenotype Chromosome Recessive Dominant Allele Heterozygous Homozygous Genetic Pedigrees Punnett Squares Genetic Probability Genotypic Ratio Phenotypic Ratio Incomplete Dominance Codominance Meiosis Germ Cell Haploid (1n) Diploid (2n) Ovaries Testes Gametes Ova/Ovum Sperm Fertilization Zygotes Embryo Autosomal trait Sex-linked trait (or X-linked) Trisomy / Monosomy Homologous Pair Sister Chromatids Independent Assortment Crossing Over/GeneticRecombination Nondisjunction Generations (P, F1, F2) Pedigree Karyotype Autosomes Sex Chromosomes Chromosomal Abnormalities (numbers and/or structures) “To do” list and tips for studying: Form a small study group and discuss all of the following. Understand all terms above and be able to put them into context. Pick three words (at random) and be able to form one sentence, incorporating all ideas together. Review all journal entries, notes, and returned/stamped/scored/unscored work. Make corrections where appropriate and review corrections. Be able to interpret Punnett Square problems and simple family pedigrees. Be able to explain the Meiosis Profile (who does it, when does it happen, where does it happen, why does it happen, how). Be able to interpret a human karyotype and understand its uses. Be able to complete genetics problems involving sex-linked traits, complete dominance, codominance, and incomplete dominance. Know the difference between “regular” body cells and gametes (locations, functions, types, etc.) Be able to explain the relationship between chromosomes, DNA, alleles, genes, traits, genotypes, and phenotypes. Practice Problems 1. Continuity of species (the goal of reproduction) requires that individuals of a species must __________________________ their genetic information. 2. In __________________ reproduction, offspring inherit their entire DNA from one parent. 3. In __________________ reproduction, offspring inherit ____ their DNA from each of two parents. 4. How many copies of each gene do you have? _________ 5. How many chromosomes are in every human body (somatic) cell? _____________ 6. How many chromosomes are in a human gamete (sex cell)? ____________ 7. Describe the difference between asexual and sexual reproduction in terms of number of parents, variation between the offspring and parents, variation between offspring. 8. Describe in words and diagrams the process of meiosis. Include the number of chromosomes and the number of cells in each step. (You do NOT have to name all the steps). 9. If an organism has 6 chromosomes, how many chromosomes will each gamete have at the end of meiosis? 10. How many gamete cells are formed from the original cell? 11. How many chromosomes would you have in a zygote if the gametes each had 25 chromosomes in them? 12. How many chromosomes are in the germ cell that produces gametes with 11 chromosomes? 13. How many chromosomes are in a gamete that arose from a germ cell having 6 chromosomes? 14. If you have two alleles that are identical/the same, you are _______________________ for the trait. 15. In hound dogs floppy ears (F) are dominant to straight ears (f): a. b. What is the phenotype of a hound dog that is heterozygous for ear shape? What would be the genotype of a hound dog with floppy ears? 16. What do you call a gene that hides or masks another (different) one? 17. Label each of the following as homozygous or heterozygous. a. HH _____________________________ b. Tt _______________________________ 18. Label each of the following as a genotype or a phenotype. a. Blue eyes _______________________________ b. Hh _______________________________ 19. In pea plant height, tall is dominant and short is recessive. If you cross a heterozygous tall pea plant with a short pea plant, what are the phenotypic and genotypic ratios? Parents: _____ x _____ Genotypic ratio ________ : ________ : ________ TT Tt tt Phenotypic ratio ________ : ________ Tall short 20. In snapdragons, flower color is controlled by incomplete dominance. The two alleles are red (R) and white (W). a. b. c. What is the genotype of a snapdragon with red flowers? What is the genotype of a snapdragon with white flowers? What is the genotype of a snapdragon with pink flowers? 21. If you cross two pink snapdragons, what is the probability of producing the following kinds of flowers: a. Red ___________ % b. White ___________ % Parents: ______ x _____ c. Pink ___________ % Some traits like fur color and human blood types are controlled by yet another form of inheritance: Codominance. This is where two alleles are equally dominant (like blood types A and B, having the alleles A and B respectively) over a recessive allele (blood type O), but when paired together (like AB), both show up in the phenotype. Observe the following table for how codominant alleles interact with each other to produce the various offspring genotypes and therefore genotypes. Write a statement here to explain, in your own words, how codominance is different from incomplete dominance and complete dominance: 22. In some cows, the gene for color is controlled by codominance. The allele for red is R and the allele for white is W. The heterozygous trait is known as roan (red and white spotted fur). a. What is the genotype for a red cow? ________ b. What is the genotype for a white cow? ________ c. What is the genotype for a roan cow? ________ 23. If you cross a roan cow and a red cow, what are the probable offspring they will produce? Parents: ________ x ________ Red _____________ % White _____________ % Roan ____________ % 24. What are the sex chromosomes in a human female? ___________ male? _________ 25. In humans, the gene for color-blindness is sex-linked (X-linked) and recessive. Cross a normal vision heterozygous female ( XCXc ) with a color-blind male ( Xcy ) Parents: ___________ x ____________ a. What are all of the possible genotypes of the offspring? _________________________________________ b. What are the possible phenotypes of the offspring? __________________________________________ c. What is the probability they will have a colorblind son? d. What is the probability they will have a colorblind daughter? ______% chance 26. What are two roles of the chromosomes? ______% chance A dihybrid cross is like a Punnett Square in that it uses parent information to infer possible offspring genotype combinations, but it tracks two traits being passed down together instead of one and the traits are both heterozygous. The possible parent combinations result in unique offspring combinations. Follow the same rules in combining alleles to determine possible offspring genotypes as you would in a normal Punnett Square. 27. In pea plants smooth seeds (S) is dominant to wrinkled seeds (s). Yellow seed color (Y) is dominant to green seed color (y). Two pea plants heterozygous for both traits are crossed in the Punnett square above. a. What genotype should be in square A? ________________ b. What genotype should be in square B? ____________ c. What is the phenotype of the offspring in square B? ___________________________________ d. How many of the offspring in this cross will be expected to be wrinkled and green? _____out of 16. 28. Create a pedigree showing the following members of a family for the Sickle Cell Disease (recessive disease, NOT sexlinked) Mother – carrier (heterozygous) for Sickle Cell Disease Father – carrier (heterozygous) for Sickle Cell Disease Son – affected by Sickle Cell Disease Son – carrier for Sickle Cell Disease Son – affected by Sickle Cell Disease Daughter – no Sickle Cell Disease 29. Color in the pedigree using the following information Colorblindness is a recessive, sex-linked disorder. Grandma and Grandpa are NOT colorblind. Mickey is colorblind; all of their other children have normal color vision. Sonny and John both inherited colorblindness, as did their cousins Barney and Janet. Grandpa Liz David Fred Grandma Wilma Michelle Mickey Monica Barney Sonny John Krista Janet 30. What are the genotypes of Barney, Krista, and Janet? Barney’ genotype:____________ Krista’s genotype: _____________ Janet’s genotype: _____________