Breakpoints for Interpretation of Tuberculin Skin Test (TST) Results 5 mm induration is interpreted as positive in the following circumstances: Child immunosuppressed (receiving immunosuppressive therapy or immunocompromised, including HIV infection) Child is a recent contact of a person with TB or suspected TB disease Radiograph or clinical evidence suggestive of TB disease Fibrotic changes on chest x-ray consistent with prior TB 10 mm induration is interpreted as positive in the following circumstances: Child younger than 4 years of age Child with medical conditions such as: Lymphoma Hodgkin’s disease Diabetes mellitus Chronic renal failure Malnutrition Child or parent born in a country with a high prevalence of TB Frequent exposure to high-risk adults, including adults who are HIV infected, homeless, residents of nursing homes, institutionalized, incarcerated, users of illicit drugs or migrant farm workers Child with travel to high prevalence countries All California residents 15 mm induration is interpreted as positive in the following circumstance: Child 4 years or older with no risk factors and who are not residents of California From Pediatric Tuberculosis: An Online Presentation by Ann Loeffler, MD. Produced by the Francis J. Curry National Tuberculosis Center.