Myritol 880
UV-filter Solubility
For checking the ability of an emollient to solubilize UV-filters four different filters
are used, i.e. Neoheliopan BB, Parsol 1798, Eusolex 6300 and Uvinul T150.
These are the most common UV-filters incorporated in sun application
formulations.
a. Neoheliopan BB (Haarmann und Reimer)
= Benzophenone 3 (2-Hydroxy-4-Methoxybenzophenon = Oxybenzon)
OH
O
H3C O
C
Concentrations:
EU: max. 10%
USA: max. 6%
JP: max. 5%
CAS-Nr.
EINECS-Nr.
131-57-5
205-031-5
mp.: 63-65°C
also called: Eusolex 4360 (Merck)
b.
Parsol 1789 (Roche)
O
O
H3C O
= Butylmethoxydibenzoylmethan
Concentrations:
EU: max. 5%
USA: max. 3%
JP: max. 10%
CAS-Nr.
EINECS-Nr.
70356-09-1
274-581-6
mp.: 81-86°C
also called: Eusolex 920 (Merck)
c.
Eusolex 6300 (Rona/Merck)
H3C
CH3
CH3
O
CH
CH3
= 4-Methylbenzylidenecamphor
Concentrations:
EU: max. 4%
CAS-Nr.
EINECS-Nr.
mp.: 65-68°C
38102-62-4
253-242-6
36861-47-9
d. Uvinul T 150 (BASF)
= Ethylhexyltriazone, R: Ethylhexyl-residue
COOR
NH
N
NH
ROOC
N
N
HN
COOR
Concentrations:
EU: max. 5%
JP: max 3%
CAS-Nr.
EINECS-Nr.
88122-99-0
mp.: 130.3°C
Test procedure:



30 ml bottle with lid
for unknown emollients: 10, 20, 30, 40 % UV-filter (UVF)
total amount (emollient + UVF): 10 g





stirring at 50°C in water bath (temperature below m.p. of UVF)
if UVF is solubilized immediately: 15 min stirring, if not: 90 min stirring
cooling down to room temperature
storing the same sample: first for 3 days at 23°C, then 7 days at 15°C
double determination for reproducibility


after determination of solubility in 10% steps, investigations of 5% steps
final values in % at 15°C
Product
Myritol 331
Uvinul T150 [%] 7 Parsol 1798 [%] 7 Neoheliopan BB [%] Eusolex 6300 [%]
days 15°C
days 15°C
7 days 15°C
7 days 15°C
10
10
10
20
15
10
15
25
Chg:CB0120004
Myritol 880
Japan 021192
A slightly better solubility of the filters Uvinul T 150 , Neoheliopan BB and
Eusolex 6300 can be observed for Myritol 880 compared to Myritol 331.