PARSOL® 1789
DSM Nutritional Products
Description
Comparative UV absorption spectra of
PARSOL® 1789 vs. Benzophenone-3
PARSOL® 1789 is an oil-soluble UV-A filter.
(1 0 mg/ L in absolute ethanol)
Absorbance
Chemical structure
Benzophenone-3
PARSOL® 1789
1.5
1
0.5
0
C20H22O3
Mr 310.4
250
300
350
400
Wavelength (nm)
CAS No.:
EINECS No.:
INCI name:
Chemical name:
70356-09-1
274-581-6
butyl methoxydibenzolymethane
1-(4-tert-butylphenyl)-3- (4methoxyphenyl)-propane-1, 3-dione
USAN nomenclature: avobenzone
Physical and chemical properties
Appearance:
Odour:
Melting point:
Assay (HPLC):
UV specific extinction
(E 1%, 1 cm at 357 ±2 nm
in absolute ethanol):
Flash point (liquid):
white to pale yellow powder
slightly aromatic
81.0–86.0 °C
min. 95.0%
1100–1180
> 100 °C (212 °F)
UV absorption spectra
PARSOL® 1789
Absorbance
2.5
99.7
PARSOL® 1789 is incompatible with formaldehyde,
formaldehyde donor preservatives and heavy
metals (pink-orange colour with iron). A sequestering agent is recommended. Formulations with
PABA and its esters develop a yellow colour.
Can form complexes with aluminium above pH 7,
with free aluminium resulting from the coating of
some grades of microfine pigments.
The product may be stored for 24 months from the
date of manufacture in the unopened original
container and at a temperature below 25 °C. The
‘best used before’ date is printed on the label.
Store in tight containers protected from light.
Suitable materials for containers are stainless
steel, dark glass, polyethylene and enamel.
96.8
1
90.0
0.5
68.4
0
0
250
Uses
99.0
1.5
300
350
400
Wavelength (nm)
Blend of PARSOL® 1789 and PARSOL® MCX
50/5 0 w/ w
Absorbance
Absorbtion (%)
2.5
10 mg/L
20 mg/ L
40 mg/L
2
99.7
99.0
1.5
96.8
1
90.0
0.5
68.4
0
0
250
Stability and storage
Absorbtion (%)
5 mg/ L
10 mg/L
20 mg/ L
2
Instrument:
Uvikon 941
Cell thickness: 1 cm
Solvent:
absolute ethanol
300
350
Wavelength (nm)
400
PARSOL® 1789, combined with recognized safe
and effective UV-B filters, provides broad-spectrum protection in skin and sun-care preparations.
PARSOL® 1789 can be used for the formulation of
protective hair-care, medicated skin-care and
protective skin-tone preparations.
It can be used to quench phototoxic skin reactions
initiated by weak phototoxic materials.
Solubility
Solvent
Solubility
(% w/w, 20 °C)
PARSOL MCX (octyl methoxycinnamate)
25
Crodamol DA (diisopropyl adipate)
19
Miglyol 812 (caprylic/capric triglyceride)
14
Finsolv TN (C12-C15 alkyl benzoate)
14
Cetiol HE (peg-7 glyceryl cocoate)
12
Cetiol A (hexyl laurate)
11
Finsolv SB (isostearyl benzoate)
11
Deltyl Extra (isopropyl myristate)
10
Estol 1517 IPP (isopropyl palmitate)
10
Finsolv BOD (octyldodecyl benzoate)
10
Dermol 105 (isodecyl neopentanoate)
9
Cetiol LC (coco-caprylate/ caprate)
9
Hetester FAO (C12-C15 alkyl octanoate
9
Finsolv P (PPG-15 stearyl ether benzoate)
9
Arlamol E (PPG-stearyl benzoate)
8
Cetiol 868 (octyl stearate)
8
Cetiol V (decyl oleate)
8
Crodamol cap (cetearyl octanoate)
7
Elefac I-205 (octyldodecyl neopentanoate)
6
Isopropyl alcohol (99%) (isopropanol)
2
Ethyl alcohol 96% vol.(ethanol)
2
Light mineral oil (mineral oil)
1
Propylene glycol (propylene glycol)
0.2
Silicone 344 fluid (cyclomethicone)
0.2
Glycerin
0.1
Water
Insoluble
Best results are obtained when part of the Na2
EDTA is added to the oil phase. Preservative
agents must be selected carefully (see table
below). Avoid formaldehyde donors.
Stabilizing additives
• Chelating materials to prevent coloration with
metallic ions
• Antioxidants
Recommended preservative agents
Commercial name INCI name
Phenonip
Phenoxyethanol &
methylparaben &
ethylparaben &
propylparaben
& butylparaben
Nipagin
M Methylparaben
Phenoxetol
Phenoxyethanol
Kathon CG
Methylchloroisothiazolinone
& methylisothiazolinone
Irgasan DP 300
Triclosan
Glycacil-L
Iodopropynyl
butylcarbamate
Nipaguard DCB
Methyldibromo glutaronitrile
Benzoic acid
Benzoic acid
Materials to be avoided
Recommended use levels
Formulate according to local regulations. See also
Regulatory status.
In sunscreen products:
2–3%
In everyday skin-care products:
1–2%.
• Iron and ferric salts
• Heavy metals
• Formaldehyde donors
• PABA and PABA
esters
Regulatory status
Formulating techniques and handling
tips
TSCA/EEC:
USA:
PARSOL® 1789 is oil-soluble and should be
incorporated into the heated oil phase.
Consult the table Solubility to ensure that
PARSOL® 1789 is properly dissolved, in order to
avoid the formation of crystals.
To avoid the formation of complexes of PARSOL®
1789 with metals, it is recommended to add
0.05–0.1% of disodium EDTA.
EU:
Japan:
registered
approved, at levels of maximum 3%
alone (at least SPF 2) and 2–3% in
combination with other
UV sunscreens. See Federal
Register Vol.62, No.83, April 30,
1997 /Rules and Regulations,
outlining conditions under which
PARSOL® 1789 can be marketed in
the USA.
listed in Council Directive
76/768/EEC, Annex VII,
Part I: max. 5%.
JSCI/JCID listed.
The Science In Beauty
Many of the leading cosmetics and personal care companies have realized the synergy
between vitamins, sunscreens, omega-6 oils and phospholipid emulsifiers, and are
incorporating them into their products at the proper levels, utilizing innovative delivery
systems and technologies to develop functional, high performance cosmetics.
In addition to having invented the synthesis of many of these ingredients, at DSM Nutritional
Products we have explored the science behind the activity of these ingredients and
developed concepts, addressing specific global and especially Asian trends in hair care,
skin care and oral care.
Unlimited. Cosmetics
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The information given in this leaflet is based on our current knowledge
and experience, and may be used at your discretion and risk. It does
not relieve you from carrying out your own precautions and tests.
We do not assume liability in connection with your product or its use.
You must comply with all applicable laws and regulations, and
observe all third-party rights.
DSM Nutritional Products Europe Ltd
P.O. Box 3255
CH-4002 Basel
Switzerland
www.dsmnutritionalproducts.com