On-going Research Projects

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1. Chen Q, Zhang Y, Peng H, Lei L, Kuang H, Zhang L, Ning L, Cao Y, Duan E*. Transient
β2-Adrenoceptor activation confers pregnancy loss by disrupting embryo spacing at
implantation. J Biol Chem. 2010 Dec 9. [Epub ahead of print]
2. Chen Q, Peng H, Lei L, Zhang Y, Kuang H, Cao Y, Shi QX, Ma T, Duan E*. Aquaporin3
is a sperm water channel essential for postcopulatory sperm osmoadaptation and
migration. Cell Res. 2010 Dec 7. [Epub ahead of print]
3. Peng H, Zhang Y, Lei L, Chen Q, Yue J, Tan Y*, Duan E*. Aquaporin 7 expression in
postimplantation mouse uteri: a potential role for glycerol transport in uterine
decidualization. Fertil Steril. 2010 Dec 2. [Epub ahead of print]
4. Li D, Zhou J, Wang L, Shin ME, Su P, Lei X, Kuang H, Guo W, Yang H, Cheng L,
Tanaka TS, Leckband DE, Reynolds AB, Duan E, Wang F*. Integrated biochemical and
mechanical signals regulate multifaceted human embryonic stem cell functions. J Cell
Biol. 2010 Nov 1;191(3):631-44.
5. Zhou J, Su P, Li D, Tsang S, Duan E, Wang F*. High-efficiency induction of neural
conversion in human ESCs and human induced pluripotent stem cells with a single
chemical inhibitor of transforming growth factor beta superfamily receptors. Stem Cells.
2010 Oct;28(10):1741-50.
6. Li J, Kawamura K, Cheng Y, Liu S, Klein C, Liu S, Duan EK, Hsueh AJ*. Activation of
dormant ovarian follicles to generate mature eggs. Proc Natl Acad Sci U S A. 2010 Jun
1;107(22):10280-4.
7. Kuang H, Chen Q, Zhang Y, Zhang L, Peng H, Ning L, Cao Y, Duan E*.The cytokine
gene, CXCL14, restricts human trophoblast cell invasion by suppressing gelatinase
activity. Endocrinology 2009 Dec;150(12):5596-605.
8. Chen Q, Peng H, Zhang Y, Lei L, Cao Y, Duan E*. Embryo implantation: a time for
recalling and forwarding. Chinese Sci Bull 2009, 54: 4083-4093 (Invited review)
9. Qiu ZF, Miao CL, Li J, Lei X, Liu S, Guo W, Cao Y, Duan EK*. Skeletal myogenic
potential of mouse skin-derived precursors. Stem Cells Dev 2010 Feb;19(2):259-68.
10. Zhang L, Guo W, Chen Q, Fan X, Zhang Y, Duan E*. Adam12 Plays a Role during
Uterine Decidualization in Mice. Cell and Tissue Research 2009 Dec;338(3):413-21.
11. Haibin Kuang, Qi Chen, Xiujun Fan1, Ying Zhang, Li Zhang, Hongying Peng, Yujing
Cao, Enkui Duan*. CXCL14 inhibits trophoblast outgrowth via a paracrine/ autocrine
manner during early pregnancy in mice. Journal of Cellular Physiology. 2009, 221:
448-457
12. Zhou J, Su P, Wang L, Chen J, Zimmermann M, Genbacev O, Afonja O, Horne MC,
Tanaka T, Duan E, Fisher SJ, Liao J, Chen J, Wang F.* mTOR supports long-term
self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem
cells. Proc Natl Acad Sci U S A. 2009, 106(19):7840-5
13. Ying Zhang, Sha Peng, Haibin Kuang, Qi Chen, Shuang Liu, Li Zhang and Enkui Duan*
Expression and regulation of Dickkopf2 during periimplantation in mice, J Reprod Dev.
2009 ,55(1):17-22
14. Kuang HB, Miao CL, Guo WX, Peng S, Cao YJ, Duan EK*Dickkopf-1 enhances
migration of HEK293 cell by beta-catenin/E-cadherin degradation., Front Biosci.
2009,14:2212-20.
15. W. Guo, C. Miao, S. Liu, Z. Qiu, J. Li, and E. Duan* Efficient differentiation of
insulin-producing cells from skin-derived stem cells, Cell Prolif. 2009,42(1):49-62.
16. Chen Q, Zhang Y, Lu J, Wang Q, Wang S, Cao Y, Wang H*, Duan E* Embryo-uterine
cross-talk during implantation: the role of Wnt signaling. Mol Hum Reprod.
2009,15(4):215-21(Invited review)
17. Liwei Jia, Jiaxi Zhou, Sha Peng, Juxue Li, Yujing Cao, Enkui Duan*. Effects of Wnt3a
on proliferetion and of human epidermal stem cells. Biochemical and Biophysical
Research Communications, 2008, 386:483-488
18. Liwei Jia, Chenglin Miao, Yujing Cao, En kui Duan*. Effects of Wnt proteins on cell
proliferation and apoptosis in HEK 293 cells. Cell Biology International,
2008,32 :807-813
19. Ping Zhao, Ananya De, Zeng Hu, Jing Li, Sabine M. Mulders, Maarten D. Sollewijn
Gelpke, En-Kui Duan*, and Aaron J. W. Hsueh*. Gonadotropin Stimulation of Ovarian
Fractalkine Expression and Fractalkine Augmentation of Progesterone Biosynthesis by
Luteinizing Granulosa Cells. Endocrinology, 2008, 149(6):2782–2789
20. Jing Li, Ph.D., Wei-Min Liu, Ph.D., Yu-Jing Cao, M.S., Sha Peng, Ph.D., Ying Zhang,
Ph.D., and En-Kui Duan, Ph.D*. Roles of Dickkopf-1 and its receptor Kremen1 during
embryonic implantation in mice. Fertility and Stertility, 2008,90(4):1470-1479
21. Juxue Li, Chenglin Miao, Weixiang Guo, Liwei Jia, Jiaxi Zhou, Baohua Ma, Sha Peng,
huang Liu, Yujing Cao. Enkui Duan*. Enrichment of putative human epidermal stem
cells based on cell size and collagen type IV adhesiveness. Cell Research 2008,
18:360-371
22. Bao-Hua Ma, Yu-Jing Cao, Wei-Bo Zheng, Jin-Ren Lu, Hai-bin Kuang, Xiao-Hua Lei,
Yin-Huan Lv, Tao Zhang, En-Kui Duan*. Real-Time Micrography of Mouse
Preimplantation Embryos in an Orbit Module on SJ-8 Satellite. Microgravity Sci. Technol
2008, 20:127–136
23. Peng S, Li J, Miao C, Jia L, Hu Z, Zhao P, Li J, Zhang Y, Chen Q, Duan E*. Dickkopf-1
secreted by decidual cells promotes trophoblast cell invasion during murine placentation.
Reproduction. 2008 ,135(3):367-75
24. Shuang Liu and Enkui Duan*. Advances in the study on induced pluripotent stem cells.
Chinese Science Bulletin,2008,53 (5):709-717
25. Yu-jing Cao, Xun-jun Fan, Zheng Shen, Bao-hua Ma, En-kui Duan*. Nitric oxide affects
preimplantation embryonic development in a rotating wall vessel bioreactor simulating
microgravity. Cell Biology Internationl. 2007, 31 (1): 24-29
26. Liu WM, Cao YJ, Li J, Fan XJ, Zhao P, Duan EK*. The expression of CD9 in the
peri-implantation mouse uterus is up-regulated in an ovarian steroid hormone-dependent
manner. Fertility and Sterility.2007, 87(3):664-670
27. Sha Peng, Chenglin Miao, Jing Li, Xiujun Fan, Yujing Cao and Enkui Duan*. 2006
Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of
canonical
Wnt
signaling.
Biochemical
and
Biophysical
Research
Communications. ?2006, 350(3):641-647
28. Jiaxi Zhou, Liwei Jia, Weimin Liu, Chenglin Miao, Shuang Liu, Yujing Cao, and Enkui
Duan*. Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the
human fetal epidermis. Human Reproduction. 2006,21(7):1698-1704
29. Shumin Bu, Chenfu Cao, Yongjun Yang, Chenglin Miao, Zeng Hu, Yujing Cao,
Qingxiang Amy Sang, and Enkui Duan* .Localization and temporal regulation of tissue
inhibitor of metalloproteinases-4 in mouse ovary. Reproduction. 2006,131: 1099-1107
30. Weiming Liu, Yujing Cao, Yongjun Yang, Zheng Hu, and Enkui Duan*. Tetraspanin CD9
regulates invasion during mouse embryo implantation. Journal of Molecular
Endocrinology. 2006,36:121–130
31. Yongjun Yang, Weimin Liu, Jiaxi Zhou, Yujing Cao, Jing Li, Sha Peng, Li Wang,
Jianggang Yuan, and Enkui Duan*. Expression and hormonal regulation of
calcyclin-binding protein (CacyBP) in the mouse uterus during early pregnancy.Life
Science. 2006, 78(7):753-760
32. Yongjun Yang, Yujing Cao, Shumin Bo, Peng Sha, Weimin Liu, and Enkui Duan*.
Leptin-directed embryo implantation: Leptin regulates adhesion and outgrowth of mouse
blastocysts and receptivity of endometrial epithelial cells. Animal Reproduction Science.
2006, 92(1-2):155-167
33. Shumin Bu, Yongjun Yang, Chenglin Miao, Hongjiang Li, Robert G. Newcomer,
Qingxiang ?Amy Sang ,and Enkui Duan*. Developmental and hormonal regulation of
meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life.
Life Science.2006, 79(22):2112-2118
34. Jing Li, Jian Zhang, Yujing Cao, Jiaxi Zhou, Weimin Liu, Xiujun Fan, and Enkui Duan*.
Inhibition of the Beta-Catenin Signaling Pathway in Blastocyst and Uterus During the
Window of Implantation in Mice. Biology of Reproduction. 2005,72(3): 700-706
35. Yi Tan*, Dongmei Tan, Mingzhong He, Meili Gu, Zhibiao Wang, Guoqing Zeng, and
Enkui Duan. A Model for Implantation: Co-Culture of Blastocysts and Uterine
Endometrium in Mice. Biology of Reproduction. 2005,72 (3):556-561 (highlight paper)
36. Li Wang, Enkui Duan, Liying Sung, ByeongSeon Jeong, Xiangzhong Yang, and X Cindy
Tian. Generation and characterization of pluripotent stem cells from cloned bovine
embryos. Biology of Reproduction. 2005,73(1):149-155
37. Jiaxi Zhou, Shuyi Chen, Weimin Liu, Yujing Cao, and Enkui Duan*. Enrichment and
identification of human 'fetal' epidermal stem cells.Human Reproduction.
2004,19(4):968-974 (Cover paper)
38. Jiaxi Zhou, Liwei Jia, Yongjun Yang, Sha Peng, Yujing Cao, and Enkui
Duan*.Enrichment and characterization of mouse epidermal stem cells. Cell Biology
International.2004,28(7):523-529
39. Jian Zhang, Yunge Zhao, Yujing Cao, Qingxiang Amy Sang, and Enkui
Duan* .Expression and implications of tissue inhibitor of metalloproteinases-4 in mouse
embryo. Molecular Human Reproduction. 2003,9(3):143-149. (Cover paper).
40. Liquan Cai, Jian Zhang, and Enkui Duan*. Dynamic distribution of epidermal growth
factor during mouse embryo peri-implantation. Cytokine.2003,23(6): 170-178
41. Bojie Dai, Yujing Cao, Jiaxi Zhou, Sumin Li, Xichao Wang, Dayuan Chen,
Enkui ?Duan*. Abnormal expression of matrix metalloproteinase-2 and -9 in
interspecific pregnancy of rat embryos in mouse recipients. Theriogenology. 2003,60(7):
1279-1291
42. Bojie Dai, Yujing Cao, Weimin Liu, Sumin Li, Yongjun Yang, Dayuan Chen, and Enkui
Duan*. Dual roles of progesterone in embryo implantation in the mouse. Endocrine.
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2003,21(2):123-132
Jian Zhang, Yujing Cao, Fuyang Li, Jing Li, Libo Yao, and Enkui Duan* Effects of
Fibronectin, VEGF and Angiostatin on the Expression of MMPs through different
signaling pathway in the JEG-3 cells. American Journal of Reproductive
Immunology.2003,50:273-285
Wang HM, Li QL, Lin HY, Yu XD, Qian D, Dai JJ, Duan EK, and Zhu C. Expression of
vascular endothelial growth factor and its receptors in the rhesus monkey (Macaca
mulatta) endometrium and placenta during early pregnancy. Molecular Reproduction
Development. 2003,65(2):123-131
Jian Zhang, Yujing Cao, Yunge Zhao, Qingxiang Amy Sang, and En-Kui Duan*.
Expression of matrix metalloproteinase-26 and tissue inhibitor of metalloproteinases 4 in
human normal cytotrophoblast cells and a choriocarcinoma cell line, JEG-3. Molecular
Human Reproduction. 2002,8(7): 659-666 (Cover page paper)
Aizhen Xiao, Yunge Zhao, Enkui Duan *. Expression and regulation of fatty-acid amide
hydrolase gene in the rat uterus during the estrous cycle and peri-implantation period.
Molecular Human Reproduction. 2002,8(7): 651-658.
Weiming Liu,Enkui Duan*, Yujing Cao, and Guo Zeng. Effects of anandamide on
embryo implantation in the mouse. Life Sciences.2002,71(14):1623-1632
Zhiyun Jia, Enkui Duan, Zhigang Jiang*, and Zuwang Wang. Copulatory plugs in
masked palm civets: Prevention of semen leakage, sperm storage, or chastity
enhancement Journal of Mammalogy. 2002, 83(4):1035-1038
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