What are Okazaki Fragments

advertisement
Humane Genome Project Influence
Bioinformatics and Computational Biology
Informatics is the creation, development, and operation of databases and other
computing tools to collect, organize, and interpret data.
Continued investment in current and new databases and analytical tools is critical
to the future usefulness of HGP data. Databases must adapt to the evolving needs
of the scientific community and must allow queries to be answered easily. Planners
suggest developing a human genome database, analogous to model organism
databases, that will link to phenotypic information. Also needed are databases and
analytical tools for studying the expanding body of gene-expression and functional
data, for modeling complex biological networks and interactions, and for collecting
and analyzing sequence-variation data.
Some goals of this area related to the HGP are:

Improve content and utility of databases.

Develop better tools for data generation, capture, and annotation.

Develop and improve tools and databases for comprehensive functional studies.

Develop and improve tools for representing and analyzing sequence similarity
and variation.

Create mechanisms to support effective approaches for producing robust,
exportable software that can be widely shared.
Medicine
The medical industry is building upon the knowledge, resources, and technologies
emanating from the HGP to further understanding of genetic contributions to
human health. As a result of this expansion of genomics into human health
applications, the field of genomic medicine was born. Genetics is playing an
increasingly important role in the diagnosis, monitoring, and treatment of diseases.
Some specific areas of application are:

Medical genetics, genetic counseling, genetic nursing

Gene testing, gene therapy

Organ transplantation, fertility, and reproduction

Public health

Pharmaceutical industry and suppliers

Pharmacogenomics

Chemical, vaccine, medicine development and production

Database development.

Communication, work with regulatory agencies
Biotechnology
Almost everyone will be affected by applications of information and technologies
derived from the HGP era of the late 20th century. Entirely new approaches will
be implemented in biological research and the practice of medicine and
agriculture. Genetic data will provide the foundation for research in many
biological subdisciplines, leading to an unprecedented understanding of the inner
workings of whole biological systems. The benefits of genomic research are, or
soon will be, realized in such areas as ecology and environmental science, toxicwaste cleanup, creation of new bioenergy sources and more efficient industrial
processes, all these areas related with biotechnology.
The biotechnology industry has more than tripled in size between 1992 and 2001,
with revenue increasing from $8 billion to $27.6 billion. In 2001, there were
191,000 U.S. employees, and more opportunities are expected in healthcare, food
production, and environmental cleanup
Some specific areas of application are:
Agriculture and Wildlife

Genetic modification of foods and seeds

Biopesticide and neutriceutical development

Wildlife management: Identification, protection of endangered species

Authentication of consumables such as wine, caviar.
Engineering disciplines

Bioprocessing chamber, vat design and production

Toxic-waste cleanup

Instrumentation development

Creation of new energy sources via engineering, life science research

Biomedical engineering
Homework done by:
Camilo Mancera Arias
Download