multislice computer tomographic angiography

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1983 Cat 11 PET/MRI/CT
MULTISLICE COMPUTER TOMOGRAPHIC ANGIOGRAPHY FOR
EVALUATION OF PATIENTS UNDERGOING LIVER TRANSPLANTATION
GJ Friedrich1, S Abbrederis3, O Pachinger1, D zurNedden2, I Graziadei3, E Gassner2,
W Vogel3, GM Feuchtner2
1 University Hospital, Cardiology Dept, Innsbruck, Austria
2 University Hospital, Radiology Dept, Innsbruck, Austria
3 University Hospital, Gastroenterology Dept, Innsbruck, Austria
Objective: Multislice Computer Tomographic Calcium Scoring (CCS)combined with
angiography (MSCTA) of coronary arteries is a reliable imaging modality to detect
coronary artery disease (CAD). Patients (pts) with end-stage liver disease, scheduled for
transplantation (Ltx), often present with a higher bleeding risk during invasive coronary
angiography (CA) and are not suitable for stress testing. We evaluated the potential of
MSCTA to evaluate CAD in these pts compared to CA.
Methods: ECG gated contrast enhanced 16 row MSCTA (Siemens, Forchheim,
Germany)with CCS were performed in 27 pts scheduled for Ltx. All pts presented
without angina symptoms, only 10 were suitable for stress testing with negative results.
Pts with a low CCS(under 30) and normal MSCTA had no CA. CCS pts higher than 30,
with or without pathologic MSCTA (stenotic plaques) and pts with low CCS and positive
MSCTA were compared to CA.
Results: A total of 27 pts were investigated: 15 pts, with CCS under 30 and negative
MSCTA, were considered low risk candidates for Ltx without CA. 12 pts had pathologic
CCS (15 - 1519) or/and MSCTA and were referred to CA. CA documented diffuse CAD
without significant stenoses in 10 pts, 2 presented severe LAD stenoses with need for
coronary revascularization procedures. Both lesions were correctly detected by MSCTA.
Conclusion: MSCTA combined with CCS offers a reliable non-invasive imaging
modality for the assessment of CAD in pts undergoing Ltx. CA may be reserved to pts
with severe coronary pathology. Peri-and postoperative Ltx results will allow additional
information about this approach.
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