May, 2009
PERSONAL DATA
Surname and Name:
Bertrand Frédéric Rochat
Function:
Education:
Date of birth:
Nationalities:
Marital status:
Project Leader, Head of qMSF
Biochemist, PhD of the University of Lausanne
August 3rd, 1966
Swiss and French
Married, 3 children
Professional Address:
Quantitative Mass Spectrometry Facility
Faculté de Biologie et de Médecine
BH18 - 228
CHUV Hospital
1011 Lausanne
Tel. ++ 41 21 3144 41 58
Fax. ++ 41 21 314 44 88
Contact Address:
Chem du Tabousset 34A,
CH – 1040 Echallens, Switzerland
Tel. ++ 41 21 881 58 73 (home)
E-mail:
bertrand.rochat@chuv.ch
EDUCATION AND PROFESSIONAL EXPERIENCE
 Since January 2003:
Research Project Leader, in charge of the “quantitative Mass Spectrometry Facility” at the
Faculté de Biologie et de Médecine of the Centre Hospitalier Universitraire Vaudois (CHUV)
at Lausanne (Switzerland)
 March 2000 –November 2002:
Laboratory Head at Novartis Pharma (Basle) in the Unit of Bioanalytics and
Pharmacokinetics attached to the Preclinical Safety Department (animal and human studies).
Management of 3 technicians specialized in LC-MS/MS analysis working under GLP rules.
Development and validation of analytical methods. Writing of bioanalytical and
pharmacokinetic reports. In Charge of the MS system validation.
 June 1998 - January 2000:
Post-doc period at Doctor Howard L McLeod’s laboratory at Aberdeen University (Aberdeen,
Scotland).
 June 1997 - May 1998:
Post-doc period at Prof. K. L. Audus' laboratory at Kansas University (Lawrence, KS, U.S.A.).
 June 1996- May 1997:
Post-doc period at Prof. Ph. Beaune's laboratory at Université Necker (Paris, France).
 January 1992 to April 1996:
Doctorate of Science. Thesis work at the University of Lausanne (Switzerland).
Thesis Director: Prof. Pierre Baumann; Thesis Supervisor: Prof. Bernard Testa
Title: In vivo and in vitro biotransformations of the enantiomers of citalopram, a new
antidepressive drug: enzymology and clinical implications.
 1990-1991:
Research period at Nestle Research Centre (Switzerland). Toxicological test of Ames.
 1986-1990:
Master of Science University of Lausanne (Switzerland).
GRANT AND AWARDS
1998:
Annual Award of the Medical Faculty of the University of Lausanne for a PhD
research
2001:
Research Grant: Aberdeen Royal Infirmary Endowment Office and Chief
Scientist Office of Scotland
MANAGEMENT EXPERIENCE
2001-2002:
Laboratory Head at Novartis (Basle) in the Unit of Bioanalytics and
Pharmacokinetics. Management of 3 technicians specialized in LC-MS/MS
analysis working under GLP rules.
2003-2008:
Research Project Leader, in charge of the “Plateforme de Spectrométrie de
Masse”, Research department, Centre Hospitalier Universitraire Vaudois
(CHUV). Management of 3-4 technicians, 1 post-doc student and students from
the Pharmaceutical School Vaud-Genève or the HES-SO of Sion.
REVIEWER
Clinical Pharmacology and Therapeutics (impact factor 6.8)
Rapid Communication in Mass Spectrometry (impact factor 4.1)
Journal of Mass Spectrometry (impact factor 4.3)
Experimental Biology and Medicine (impact factor 2.4)
Chirality (impact factor 2.1)
Journal of Chromatography B (impact factor 2.1)
Swiss National Foundation (2007)
Biomedical Chromatography (impact factor 1.7)
TEACHING
Teaching or coaching quantitative analysis for drugs and peptides by LC-MS/MS to 3-4
technicians, post-doc fellows and students from the Pharmaceutical School Vaud-Genève
(EPGL).
INVITED SPEAKER IN INTERNATIONAL CONFERENCES
1st International Concerence in Drug Design and Discovery. 2008, Dubai. EUA
Title. Hepatic and Extrahepatic Drug Metabolizing Enzymes and Disposition of
Anti-Cancer Agents in Cancer Cells
MEMBER OF INTERNATIONAL SCIENTIFIC ORGANIZATIONS
ISSX. International Society of the Study of Xenobiotics (ISSX; issx.org).
HOBBIES
Clarinet, bass-clarinet, soprano and alto saxs, running, cycling and fine arts
PUBLICATION
See in Research and Publications at www.unil.ch/qmsf.
REFRENCES
Dr. OSCAR MARCHETTI
Dr. ERIC GROUZMANN
Dr. JEAM-LUC VEUTHEY
Dr. PIERRE BAUMANN
Dr. PHILLIPE BEAUNE
Contact addresses on request.