September 2012
PERSONAL DATA
Surname and Name:
Bertrand Frédéric Rochat
Function:
Education:
Date of birth:
Nationalities:
Marital status:
Project Leader, Head of qMSF
Biochemist, PhD of the University of Lausanne
August 3rd, 1966
Swiss and French
Married, 3 children
Professional Address:
Quantitative Mass Spectrometry Facility
Faculté de Biologie et de Médecine
BH18 – 228; University Hospital of Lausanne
CH-1011 Lausanne; Switzerland
Tel. ++ 41 21 3144 41 58
www.unil.ch/qmsf
Contact Address:
Chem du Tabousset 34A,
CH – 1040 Echallens, Switzerland
Tel. ++ 41 21 881 58 73 (home)
bertrand.rochat@chuv.ch
E-mail:
EDUCATION AND PROFESSIONAL EXPERIENCE
 Since 2003 : Research Project Leader, in charge of the “quantitative Mass Spectrometry Facility” at the
Faculté de Biologie et de Médecine of the Centre Hospitalier Universitraire Vaudois (CHUV) at Lausanne
(Switzerland). See web site at www.unil.ch/qmsf
 2000 –2002 : Laboratory Head at Novartis Pharma (Basle) in the Unit of Bioanalytics and Pharmacokinetics
attached to the Preclinical Safety Department (animal and human studies). Management of 3 technicians
specialized in LC-MS/MS analysis working under GLP rules. Development and validation of analytical methods.
Writing of bioanalytical and pharmacokinetic reports. In Charge of the MS system validation.
 1998 - 2000 : Post-doc fellow at Doctor Howard L McLeod’s laboratory at Aberdeen University (Aberdeen,
Scotland).
 1997 - 1998 : Post-doc fellow at Prof. Kenneth. L. Audus' laboratory at Kansas University (Lawrence, KS,
U.S.A.).
 1996- 1997 : Post-doc fellow at Prof. Philippe Beaune's laboratory at Université Necker (Paris, France).
 1992 to 1996 : Doctorate of Science. PhD candidate at the University of Lausanne (Switzerland).
Thesis Directors: Prof. Pierre Baumann and Prof. Bernard Testa; Title: In vivo and in vitro biotransformations
of the enantiomers of citalopram, a new antidepressive drug: enzymology and clinical implications.
 1990-1991 : Research associate at Nestle Research Centre (Switzerland). Toxicological test of Ames.
 1986-1990 : Master of Science University of Lausanne (Switzerland).
GRANT AND AWARDS
1998: Annual Award of the Medical Faculty of the University of Lausanne for a PhD research
2001: Research Grant: Aberdeen Royal Infirmary Endowment Office and Chief Scientist Office of Scotland
MANAGEMENT EXPERIENCE
2001-2002:
Laboratory Head at Novartis (Basle) in the Unit of Bioanalytics and Pharmacokinetics.
Management of 3 technicians specialized in LC-MS/MS analysis working under GLP rules.
2003-2008:
Research Project Leader, in charge of the “Plateforme de Spectrométrie de Masse”, Research
department, Centre Hospitalier Universitraire Vaudois (CHUV). Management of 3-4 technicians, 1 post-doc
student and students from the Pharmaceutical School Vaud-Genève or the HES-SO of Sion.
REVIEWER
Biomedical Chromatography (impact factor 1.7)
Chirality (impact factor 2.1)
Clinical Pharmacology and Therapeutics (impact factor 6.8)
Current Drug Targets (impact factor 4.2)
Experimental Biology and Medicine (impact factor 2.4)
Journal of Chromatography B (impact factor 2.1)
Journal of Mass Spectrometry (impact factor 4.3)
Rapid Communication in Mass Spectrometry (impact factor 4.1)
Swiss National Foundation
TEACHING
Teaching/coaching quantitative analysis by LC-MS/MS to technicians, chemists, bilogists, post-doc fellows and
students from the Pharmaceutical School Genève-Lausanne.
A course on the quantitative analyses of therapeutic and native peptides for www.cefira.com. In collaboration
with Drs. François Fenaille, François Bécher, CEA, Paris.
ORAL PRESENTATION IN INTERNATIONAL CONFERENCES
1st International Concerence in Drug Design and Discovery. 2008, Dubai. EUA
Title.
Hepatic and Extrahepatic Drug Metabolizing Enzymes and Disposition of
Anti-Cancer Agents in Cancer Cells
60th ASMS Conference on Mass Spectrometry and Allied Topics, 2012, Vancouver Canada
Title.
Simulatenous qualitative, semi-quantitative and quantitative analyses in clinical laboratories
using second generation Exactive high resolution accurate mass spectrometry
MEMBER OF INTERNATIONAL SCIENTIFIC ORGANIZATIONS
1.
2.
ISSX. International Society of the Study of Xenobiotics (www.issx.org).
ASMS. American Society of Mass Spectrometry (www.asms.org).
HOBBIES
Music: Clarinet, bass-clarinet, soprano and alto saxophones. Virtuosity diploma of the Conservatoire de
Lausanne (clarinet), 1992. Retired soldier in the Swiss Army Band (“ArmeeSpiel”). Fine arts, astronomy and
photography. Running, cycling and swimming.
REFERENCES
In public research / health organisations:
Prof. Dr. Pierre Baumann
Prof. Dr. Jean-Luc Veuthey
Prof. Dr. Philippe Beaune
Prof. Dr. Oscar Marchetti