Genetics Chapter 11- pg. 306-329 11.1 pg. 306-312 Every living this inherits characteristics from its parent/parents= heredity. Genetics: scientific study of heredity, founded by Gregor Mendel. Fertilization: process in sexual reproduction in which male and female reproductive cells join to form a new cell. Trait: specific characteristic of an individual Hybrids: offspring of crosses between parents with different traits Mendel’s first conclusion: an individual’s characteristics are determined by factors that are passed from on parental generation to the next. Gene: sequence of DNA that codes for a protein and thus determines a trait; factor that is passed from parent to offspring Allele: one of a number of different forms of a gene Principle of dominance: Mendel’s second conclusion, which states that some alleles are dominant and others are recessive. Segregation: separation of alleles during gamete formations Gametes: sex cell During gamete formation, the alleles for each gene segregate from each other, so that each gamete carries only one allele for each gene 11.2 pg. 313-318 Probability: likelihood that a particular even will occur- could be used to explain genetics Homozygous: having two identical alleles for a particular gene (TT, tt) Heterozygous: having two different alleles for a particular gene (Tt) Phenotype: physical characteristics of an organism Genotype: genetic makeup of an organism Best way to predict the outcome of a genetic cross is by using a Punnet Square o Punnett squares use mathematical probability to help predict the genotype and phenotype combinations in genetic crosses. Independent Assortment: one of Mendel’s principles that states that genes for different traits can segregate independently during the formation of gametes Accounts for the many genetic variations in plants, animals, etc. Mendel’s principles of heredity, observed through patterns of inheritance, form the basis of modern genetics. Principles: The inheritance of biological characteristics is determined by individual units called genes, which are passed from parents to offspring. Where two or more forms (alleles) of the gene for a single trait exist, some alleles may be dominant and others may be recessive. In most sexually reproducing organisms, each adult has two copies of each geneone from each parent. These genes segregate from each other when gametes are formed. Alleles for different genes usually segregate independently of each other. 11.3 pg 319-321 Some alleles are neither dominant or recessive Incomplete dominance: situation in which one allele is not completely dominant over another allele Codominance: situation in which the phenotypes produced by both alleles are completely expressed Many genes exist in several different forms and are therefore said to have multiple alleles. o Multiple Alleles: a gene that has more that two alleles Many traits are produced by the interaction of several genes Polygenic traits: trait controlled by two or more genes Environmental conditions can affect gene expression and influence genetically determined traits 11.4 pg 323-329 Homologous: term used to refer to chromosomes in which one set comes from the male parent and one set comes from the female parent Diploid: term used to refer to a cell that contains two sets of homologous chromosomes The diploid cells of most adult organisms contain two complete sets of inherited chromosomes and two complete sets of genes Haploid: term used to refer to a cell that contains only a single set of genes Meiosis: process in which the number of chromosomes per cell is cut in half through the separation of homologous chromosomes in a diploid cell Has 2 distinct divisions o Meiosis I o Meiosis II o By the end of meiosis II, the diploid cell becomes four haploid cells Meiosis I- just prior the cell replicates its chromosomes o Prophase I: In this phase, each replicated chromosome pairs with its corresponding homologous chromosome. This pairing forms: Tetrad: structure containing four chromatids that forms during meiosis Crossing-over: process in which homologous chromosomes exchange portions of their chromatids during meiosis Metaphase I and Anaphase I: spindle forms attaches to each tetrad o Metaphase I of meiosis: paired homologous chromosomes line up across the center of the cell o As the cell moves to Anaphase I, the pairs of chromosomes separate o Anaphase I of meiosis: spindle fibers pull each homologous chromosome pair toward opposite ends of the cell Telophase I and Cytokinesis: the separated chromosomes cluster at opposite ends of the cell o Telophase I: a nuclear membrane forms around each cluster of chromosomes o Cytokinesis: forms two new cells Meiosis I results in two new cells, called daughter cells. Meiosis II- two cells now enter a second meiotic division Prophase II: As the cells enter prophase II, their chromosomes- each consisting of two chromatids- become visible. Metaphase II, Anaphase II, Telophase II and Cytokinesis Metaphase II: chromosomes line up in the center of each cell Anaphase II: the pair chromatids separate The final four phases of meiosis II are similar to those is meiosis I. However, the result is four haploid daughter cells. The haploid cells produced are the gametes that are important to heredity (sperm, egg). Zygote: fertilized eggs Mitosis vs. Meiosis In mitosis, when the two sets of genetic material separate, each daughter cell receives one complete set of chromosomes. In meiosis, homologous chromosomes line up and then move to separate daughter cells. Mitosis does not normally change the chromosome number of the original cell. This is not the case for meiosis, which reduces the chromosome number by half. Mitosis results in the production of two genetically identical diploid cells, whereas meiosis produces four genetically different haploid cells.