ARTIFICIAL SELECTION Artificial Selection is the process of selecting and breeding individuals with desirable traits to produce offspring with the desired traits. The selection process is simple - only those individuals (animals or plants) with the desired trait are allowed to reproduce. Some people in history have tried to do this with humans… can anyone give an example? The main difference between 'natural' selection and 'artificial' selection is that, humans control the artificial selection process. Man has been using artificial selection for thousands of years! For example, archaeological evidence shows us that: all of today’s different types of dogs came from one type of ancestral dog that man tamed about 14000 years ago. wheat and barley (members of the grass family) were amongst the first plants grown for food → but although 80 different plants were domesticated during prehistoric times only a few today make up the majority of the world’s food supply (e.g. wheat &rice = 40%) It can take many generations for artificial selection to consistently produce the desired result. This is because the recessive genes continue to be present in the mix of some offspring until it is gradually BRED out… leaving a PUREBRED. Have you ever herd of a BEEFALO? It is a cross between a cow and a bison (or buffalo). It is a CROSS BREED. Like the bison it has thick fur to protect it from the cold and the meat is low in fat and cholesterol. 1 ARTIFICIAL SELECTION Today man uses a variety of low and high tech methods to try and speed up artificial selection in animals: cloning – making life from cells artificial insemination – artificially joining selected male and female gametes in vitro fertilization – make and female gametes are selected and then allowed to fertilize in a controlled setting before being implanted into the female genetic engineering – direct altering of DNA in an organism, then allowing it to reproduce In plants man uses selective breeding and genetic engineering to produce desired results such as resistance to disease, length of time to mature, resistance to extreme temperatures (hot or cold), and even taste. Western Red Spring Wheat used for flour to make bread and Canadian Western Duram used to make pasta are two examples of grains grown locally. Canola is another good example, selectively bred to produce lots of high quality oil (check the margarine or cooking oil in your house for this) 2 ARTIFICIAL SELECTION Genetic Engineering - moving pieces of DNA from one cell into another, even from the cell of one animal into the cell of another. We know that the DNA tells the cell what should look like and do… so what happens when scientists change the DNA? Is this a good thing?? Genetic Engineering allows scientists to move genes from one organism to another, and characteristics from one species to another. Using these methods is also called BIOTECHNOLOGIES. Biotechnology has significant implications for modern medicine. One of the 1st uses was to move the human gene for insulin production into bacteria → thus allowing the bacteria to produce insulin as a waste product. Who can suggest why this might be important? This allows us to produce large quantities of insulin which is important for diabetics who need regular insulin shots. Scientists have also created a type of bacteria that can eat oil. It would be useful to protect our environment when there are big oil spills. Do you see any down side (risk) associated with this? We have discovered how to insert human genes into some animals as well. This creates what we call a TRANSGENETIC or genetically modified animal. TRANSGENETIC animals are produced by adding human genes to the fertilized eggs of the animal. The offspring of a transgenetic animal will be able to produce the desired human proteins. For example, transgenetic cows are used to produce “human lactoferrin (milk with a high source of iron for babies). Why might transgenetics be important? Do you think there might be risks? 3 ARTIFICIAL SELECTION Other examples – sheep are used to produce factor VIII and IX which are clotting factors used to treat hemophilia and pigs are used to produce human protein C which is used to treat blood clots in humans. Transgenetics are also used in our food supply. Who has heard of Genetically Modified Organisms (GMOs)? An example is about 15 years ago the papaya industry in Hawaii was on the verge of collapse due to a virus that was destroying the fruit. Transgenetics was used – a new gene was inserted into some plants and over time the population of papaya plants in Hawaii became resistant to the virus. Can you think of some pros and cons to this? Crops such as wheat, corn, tomatoes and potatoes are genetically modified for various reasons – often to be tolerant to pesticides and herbicides. Today we tend to use fewer species of plants for food production MONOCULTURES. What are the benefits of doing this? How could such practices harm the world’s future food supply? Biotechnology is also used in fish farming or AQUACULTURE. With declining fish stocks (e.g. collapse of Atlantic cod industry), aquaculture is becoming more and more important as a way of producing fish for us to eat. Scientists have added genes for disease resistance to some varieties of fish and also growth hormones are introduced to fish eggs to increase the size and growth rate of the fish. Researchers are also adding “antifreeze” so some stocks of Atlantic salmon and halibut… the gene comes from an arctic flatfish. What might happen if these “superfish” were to escape from captivity? 4