DEPARTMENTAL POLICY AND PROCEDURE Program: University of Michigan Cardiovascular Center Pulmonary Hypertension Program Procedure Title: Guidelines for Instituting and Following Diuretics in the Pulmonary Hypertension Program Procedure Written: July 2011 Reviewed/ Revised: July 2011 Procedure Statement / Purpose: Oral diuresis in patients with chronic heart failure is indicated for symptom management. Careful consideration of renal function needs to be assessed in conjunction with any type of oral diuresis. Appropriate use of diuretics is critical as unnecessarily high doses can increase risk of hypotension and renal insufficiency and electrolyte imbalance. Indications: overload. Physician decision to initiate loop diuretic in the setting of volume Exclusions: Patients with a history of hypersensitivity to loop diuretics. Precautions: Patients with a history of sulfa allergy Signs / Symptom Monitoring: Assess patients signs and symptoms and baseline weight Protocol: Check baseline Basic and BNP if current labs are more than 1 month old Review and reinforce 2000 mg sodium restriction Initiate 2L (64 ounce) fluid restriction Initiate dose of diuretic as selected by physician. Check Basic and BNP 1 week after initiating or changing dose of diuretic o If Creatinine ≥ 1.5 mg/dl, or if Creatinine rises ≥ 0.5 mg/dl, then consult physician o If serum sodium < 125 mmol/l, then consult physician Assess patients response to diuretic 3- days after initiation or changing dose of diuretic MD Signature: ___________________________ Date: ____________ Val McLaughlin, MD Medical Director, CVM Pulmonary Hypertension Program Nurse Signature: ___________________________ Date: ____________ Janice Norville, MSN, MSBA, RN Director of Clinical Operations – CVM – Special Programs