To,
Dear Prof. Ágúst Kvaran
Respected sir,
I am very much interested in pursuing my PhD studies in your lab,
since your name is renowned in the field of organic chemistry. I have seen lot off
good papers published by your group in various journals especially in ACS
publication. I would appreciate if you can give me opportunity to work in your lab
for few months as research associate that will give me idea about your lab and also
help you to evaluate me as a potential candidate for work with you.
So, looking forward your quick and positive response.
Best Regards,
M.Purushotham
M.PURUSHOTHAM
Plot No.: 708,
Ayyappa nagar,
Police road, Hanuman Street,
Vijayawada- 520007.
Andhrapradesh.
INDIA.
Phone No: +91-9922455825
E-mail: purusharsh@yahoo.com
Objective
Looking for an opportunity to pursue my PhD studies in your lab and where my
extensive knowledge in synthetic organic chemistry will be effectively utilized.
Highlights
 Nearly nine years Job Experience in the field of Organic Synthesis.
 Extensive experience in design, synthesis (micro & macro scale), lead identification &
optimization of small molecules as potential drug candidates.
 Widely experienced and efficient in chromatography, isolation, purification and structural
determination of various kinds of organic compounds.
 Well acquainted with NMR, IR, UV, HPLC and Computer knowledge.
 An excellent Team Player having excellent communication, problem solving and
independently working skills.
Personal Details:
Date of Birth
:
7th April 1976.
Nationality
:
Indian.
Passport Number
:
E4774429.
Date of Issue
:
31st March, 2003.
Date of Expiry
:
27th August, 2008.
Father’s Name
:
M.V.Satyanarayanacharyulu.
Language Known
:
English, Telugu, Hindi.
Martial Status
:
Married.
Education
 M.Sc.: (Industrial [organic] Chemistry) from Andhra University, India, 1998.
 B.Sc.,: (Chemistry, Physics, Mathematics), from Nagarjuna University, India, 1996.
Computers

Post Graduate Diploma in Computer Applications from shivam Infotech, India, 1999.
Skills and Accomplishments
 Extensive working experience in diverse areas of organic/medicinal chemistry.
 Capable of designing, initiating and directing projects.
 Expertise in process scale-up, method validation batches, maintaining records as per
GMP/GLP requirements.
 Good organizational and managerial skills
Professional Experience
~Nine years of experience in synthesis and process development of different molecules.
 At Present I am working (from May 27, 2004 to till date) as Research Scientist in
Chembiotek Research International Ltd., Kolkata. India.
 Previously, I worked (from May 05, 2003 to May 21, 2004) as Senior Research
Chemist in G.R.Intra Chem. Limited, Hyderabad. INDIA.
 Previously, I worked (from November 01, 2001 to April 29, 2003) as Research
Associate - II in Aurobindo Pharma Limited, Hyderabad. INDIA.
 Previously I worked (July 30, 1998 to October 23, 2001) as a R&D Chemist in Laila
Impex, Vijayawada - 520 007. INDIA.
Responsibilities
 In Chembiotek Research Center (CRO), as a Research Scientist, responsibilities
includes searching literature for applicable chemistry, designing synthetic pathways
for target structures, exploring these approaches in the laboratory scale and if need
up to pilot plant scale by leading the group of four members.
 In G.R.Intra Chem Research Center, as a Senior Research Chemist, designing
synthetic pathways for target molecule/drug in patent non-infringing processes by leading
the group of six members.
 In Aurobindo Pharma Research Center, Responsibilities includes assisting our project
leader in literature search for the molecules/drugs in patent non-infringing processes and
in development of processes in laboratory scale and scale-up up to pilot plant, plant
level, as a member in the group of ten in one of senior chemist level.
 In Laila Impex Research Center, as a chemist, responsibilities include method
development of bioactive molecule/natural products by different extraction methods
and the isolation of the molecules by using different chromatographic techniques.
Implementation of the same in pilot plant followed by in bulk batches.
Strengths
 Worked on synthesis of peptides, steroids, amino acids, and carbohydrates.
 Worked on synthetic drugs like,
Pivmecillinum HCl
Sildenafil Citrate
Drotaverin HCl
Zalcitabine HCl, and etc.,
Developed the processes for many drug intermediates and APIs like,

3-[(4-chloro-1-piperidinyl) methyl]-5-methyl-piperidyne Fumarate,

2-methyl-3- (4-fluorophenyl) propionyl chloride,

Difluoro amino benzodoxime

p-Amino benzene ethanamine and etc.,
Worked on natural products/bioactive molecules like,

I have isolated two compounds namely 1,2,3,9 Tetrahydropyrrolo [2,1-b]
quinazolin-3-ol and 1,2,3,9 Tetrahydropyrrolo [2,1-b] quinazolin-3-ol from a naturally
occurring resource.

Developed semi synthetic process for 2-amino-2-deoxy-D-glucose. HCl salt and sulfate
salt from a naturally occurring resource.

Developed the process for 3, 4, 5-Trihydroxy stilbene.

Developed the process for 1,3,8-Tryhydroxy-6-methyl-9, 10anthacenedione.

Developed the molecule 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4- dione.
Analytical Experience
Expertise in column chromatography, isolation, purification and structural elucidation of
various organic compounds. Well acquainted with NMR, IR, UV, and Computer.
References:
Dr. Ram.S.Upadhayaya, Principal Scientist
Chembiotek Research International Pvt. Ltd.,
International Biotech Park, Genesis Campus,
Bio Resource Center, 3rd Floor, Phase-II,
Mulshi Hinjewadi, Pune-411057, INDIA.
Phone No: +91-9830678293.
e-mail: ramupadhayaya@rediffmail.com.
Dr. Bhanu Chanda, Scientist-E
Associate Director,
National Chemical Laboratory,
Pune, INDIA.
e-mail: bhanu@dalton.ncl.res.in