FRANCESCA LEMME
email: francesca_lemme@yahoo.co.uk
francesca.lemme@maastrichtuniversity.nl
Date of birth: 20/11/1975, Nationality: Italian
EMPLOYMENT:
University of Maastricht
PhD Student
May 2011 to May 2015
I’m working on a PhD project aimed at developing efficient multilevel designs taking into
consideration budget constraints.
London School of Hygiene and Tropical Medicine (LSHTM)
Lecturer
June 2009 to April 2011:
I worked as a lecturer for LSHTM and I was based in Mwanza Intervention Trials Unit
(Mwanza, Tanzania). The unit aimed at evaluating effective interventions against HIV and other
sexually transmitted infections.
My main duties included:
(1) Provide statistical support to all research projects carried out in MITU from their design, to
statistical analyses, to the reporting of results
(2) Provide training, mentoring and support to locally-appointed statisticians and scientists at
MITU
(3) tutoring LSHTM’s distance learning students for two modules: statistical methods in
epidemiology and basic statistics for clinical trials
(4) contribute to the preparation of scientific reports and publications
GlaxoSmithKline (GSK):
Senior Statistician
August 2005 to May 2009
I’ve worked as a Senior Statistician for GSK. I worked for both Phase I and Phase II Clinical
trials in Neurosciences. My main duties included:
(1) Provide statistical input into the design of clinical trials
(2) Provide statistical input into the development of protocols
(3) Provide statistical support to data managers on designing and setting up databases
(4) Produce statistical analysis of clinical data
(5) Provide input into the final reporting of studies
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I had strong interactions with colleagues from different disciplines, such as clinicians, study
managers, project managers, pharmacokineticists, data managers and programmers.
I’ve worked for GSK’s sites in London (UK), Verona (Italy), and Bangalore (India). In the
latter, other than providing statistical support to Phase I and Phase II projects as described
above, I provided professional and statistical trainings to statisticians employed by GSK in its
new site.
School of Health and Related Research – University of Sheffield
Research Associate
October 2004 to July 2005
I worked as a Statistician for the above school. My main activities included:
(1) Refine questionnaires used for research projects within the School. Plan and undertake
all statistical analyses relating the above questionnaires and write up findings for
publication and dissemination.
(2) Provide advice and input into quantitative aspects of research for all section members.
(3) Teach quantitative aspects of research, design and analysis of data, through lectures.
Design and deliver course materials, supervise practical work and advice students on
their progress.
(4) Provide statistical support to PhD students, undertaking their Research Degree within the
School. My support involved, in particular, developing a plan of analysis, advising on
statistical methods to employ and advising on interpretation and presentation of results.
EDUCATION:
UNIVERSITY OF MAASTRICHT
Maastricht (The Netherlands) – from May 2011 to present.
I’m employed as a PhD student
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE:
London (UK) - from September 2002 to September 2004.
I gained an MSc in Medical Statistics.
BOLOGNA UNIVERSITY – FACULTY OF STATISTICAL SCIENCES
Bologna (Italy) – from academic year 1995-1996 to academic year 1999-2000:
I graduated in Social, Demographic and Statistical Sciences with Italian mark 106/110
(equivalent to a first class British grade).
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PUBLICATIONS:
In preparation:
Lemme, F, van Breukelen G, Candel M (2015). Efficient treatment allocation in 2x2
Multicenter Trials when costs and variances are heterogeneous. (in preparation)
Lemme, F, van Breukelen G, Berger M (2015). Efficient treatment allocation in 2x2 Cluster
Randomized Trials, under heterogeneous costs and variances. (in preparation)
Published:
Lemme, F, van Breukelen G, Candel M, Berger M (2015). The effect of heterogeneous variance
on efficiency and power of cluster randomized trials with a balanced 2x2 factorial design.
Statistical Methods in Medical Research. doi:10.1177/0962280215583683
Lemme, F, van Breukelen G, Berger M (2013). Efficient Treatment Allocation in two-way
nested designs. Statistical Methods in Medical Research. doi: 10.1177/0962280213502145
Lemme, F., Doyle A. M., Changalucha J., Andreasen A., Baisley K., Maganja K., WatsonJones D., Kapiga S., Hayes J. R., Ross D. A. (2013). HIV Infection among young people in
Northwast Tanzania: the role of biological, behavioural and socio-demographic risk factors.
PLoS ONE, 8(6): e66287
Watson-Jones D., Baisley K., Ponsiano R., Lemme F., Remes P., Ross D., Kapiga S., Mayaud
P., de Saniose’ S., Wight D., Changalucha J., Hayes R. (2012). Human papillomavirus
vaccination in Tanzania schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery
strategies. The Journal of Infectious Diseases, 206(5):678-86
Moolenaar M., Rad M., Zamuner S., Cohen A. C., Lemme F., Franson K. L., Van Gerven J. M.
A., Merlo Pich E., (2011). Central nervous system effects of the interaction between risperidone
(single dose) and the 5-HT6 antagonist SB-742457 (repeated doses) in healthy males. British
Journal of Clinical Pharmacology, 71(6):907-16.
Tompson D. J., Ali I., Oliver-Willwong R., Job S., Zhu L., Lemme F., Hammer A. E., Vuong
A., Messenheimer J. A.. (2007). Steady-state pharmacokinetics of lamotrigine when converting
from a twice-daily immediate-release to a once-daily extended release formulation in subjects
with epilepsy (The COMPASS Study). Epilepsia, 49(3): 410-417
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Saxon D., Fitzgerald G., Houghton S., Lemme F., Saul C., Warden S., Racketts T., (2007).
Psychotherapy provision, socioeconomic deprivation and the inverse care law. Psychotherapy
Research, 17(5):515-521
Naylor P., Cowie H., Cossin F., De Bettencourt R., Lemme F., (2006). Teachers’ and Pupils’
definitions of bullying. British Journal of Educational Psychology, 76, 553-576
Brooker C., Ricketts T., Bennett S., Lemme F., (2005). Admission decisions following contact
with an emergency mental health assessment and intervention service. Journal of Clinical
Nursing. 16, 1313-1322
Conference abstracts:
Lemme F. The effect of heterogeneous variance on efficiency and power of cluster randomized
trials with a balanced 2x2 factorial design. Leuven Statistical Day, December 2014
Lemme F. The effect of heterogeneous variances on the efficiency and power of a 2x2 cluster
randomized trial. IBS Conference, Florence, July 2014
Lemme F. Efficient treatment allocation in two-way nested designs. ISCB Conference, Munich
August 2013
Lemme F. HIV Infection among young people in Northwast Tanzania: the role of biological,
behavioural and socio-demographic risk factors. AIDS Conference, Vienna, July 2010
Lemme F. Factors associated with HSV-2 infection among young people in northwest
Tanzania. AIDS Conference, Vienna, July 2010
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