MACS Cytokine Secretion Assay Reference List
(MACS paper number)
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Altfeld, A; Addo, MM; Eldridge, RL; Yu, XG; Thomas, S; Khatri, A; Strick, D; Phillips, MN; Cohen,
GB; Islam, SA; Kalams, SA; Brander, C; Goulder, PJ; Rosenberg, ES; and Walker, BD. Vpr Is
Preferentially Targeted by CTL During HIV-1 Infection J Immunol 167: 2743-2752. 2001
Assenmacher, M; Löhning, M; Scheffold, A; Manz, RA; Schmitz, J; Radbruch, A Sequential production
of IL-2, IFN-g and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.
Eur. J. Immunol. 28: 1534-1543. 1998 (483)
Bickham, K; Münz, C; Tsang, ML; Larsson, M; Fonteneau, J-F; Bhardwaj, N; Steinmann, R EBNA1specific CD4+T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function. J. Clin.
Invest. 107: 121-130. 2001 (1035)
Brosterhus, H; Brings, S; Leyendeckers, H; Manz, RA; Miltenyi, S; Radbruch, A; Assenmacher, M;
Schmitz, J Enrichment and detection of live antigen-specific CD4+ and CD8+ T cells based on cytokine
secretion. Eur. J. Immunol. 29: 4053-4059. 1999 (573)
Brosterhus, H; Brings, S; Manz, RA; Miltenyi, S; Radbruch, A; Assenmacher, M; Schmitz, J Rapid
Enrichment and Characterization of Live Antigen-Specific T Cells Using Cellular Affinity Matrix
Technology. 10th International Congress of Immunology, New Delhi, India. 1998 (545)
Farrar, JD; Ouyang, W; Löhning M, Assenmacher M, Radbruch A, Kanagawa, O; Murphy KM An
Instructive Component in T helper cell type 2 (Th2) Development Mediated by GATA-3 J. Exp. Med.
193: 643 – 648. 2001 (972)
Hu-Li, J; Pannetier, C; Guo, L; Löhning, M; Gu, H; Watson, C; Assenmacher, M; Radbruch, A; Paul, W.
Regulation of Expression of IL-4 Alleles: Analysis Using a Chimeric GFP/IL-4 Gene. Hu-Li, J;
Pannetier, C; Guo, L; Löhning, M; Gu, H; Watson, C; Assenmacher, M; Radbruch, A; Paul, WE;
Immunity, 14: 1-11, 2001. (971).
Keenan RD, Ainsworth J, Khan N, Bruton R, Cobbold M, Assenmacher M, Milligan DW, Moss PA.
Purification of cytomegalovirus-specific CD8 T cells from peripheral blood using HLA-peptide
tetramers. Br J Haematol. 2001 Nov;115(2):428-434.
Manz, R; Assenmacher, M; Pflüger, E; Miltenyi, S; Radbruch, A Analysis and Sorting of Live Cells
According to Secreted Molecules Relocated to a Cell-Surface Affinity Matrix. Proc. Natl. Acad. Sci.
USA 92: 1921-1925. 1995 (139)
McNeil AC, Shupert WL, Iyasere CA, Hallahan CW, Mican J, Davey RT Jr, Connors M. High-level
HIV-1 viremia suppresses viral antigen-specific CD4+ T cell proliferation. Proc Natl Acad Sci,
98(24):13878-83. 2001.
Münz C; Bickham KL; Subklewe M; Tsang MS; Chahroudi A; Kurilla MG, Zhang D; O‘Donnell M;
Steinman RM Human CD4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus
Nuclear Antigen EBNA1 J. Exp. Med. 191: 1649-1660. 2000 (920)
Oelke, M; Kurokawa,T; Hentrich, I.; Behringer, D; Cerundolo, V; Lindemann, A; Mackensen, A
Functional Characterization of CD8+ Antigen-Specific Cytotoxic T Lymphocytes after Enrichment
Based on Cytokine Secretion: Comparison with the MHC-Tetramer Technology Scand. J. Immunol. 52.
544-549. 2000 (970)
Oelke, M; Moehrle, U; Chen, JL; Behringer, D; Cerundolo, V; Lindemann, A; Mackensen, A Generation
and purification of CD8+ Melan-A-Specific Cytotoxic T Lymphocytes for Adoptive Transfer in Tumor
Immunotherapy Clin. Cancer Res. 6: 1997-2005. 2000 (663)
Ouyang, W; Löhning, M; Gao, Z; Assenmacher, M; Ranganath, S; Radbruch, A; Murphy, KM Stat6Independent GATA-3 Autoactivation Directs IL-4-Independent Th2 Development and Commitment.
Immunity 12: 27-37. 2000 (597)
Pittet, MJ; Zippelius, A; Speiser, DE; Assenmacher, M; Guillaume, P; Valmori, D; Lienard, D; Lejeune,
F; Cerottini, JC; Romero, P Ex vivo IFN-g secretion by circulating CD8 T lymphocytes: Implications of
a novel approach for T cell monitoring in infectious malignant diseases. J. Immunol. 166: 7634-7640.
2001 (1037)
Smits, HH; van Rietschoten, JGI; Hilkens, CMU; Sayilir, R; Stiekema, F; Kapsenberg, ML; Wierenga, EA
IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness
and loss of GATA-3 expression Eur. J. Imm. 31 4: 1056 – 1065. 2001 (983)