BIOLOGY II Chapter 3: Cells I. Introduction NAME_________________ A. An adult human body consists of about _______________________________________________ cells. B. There are at least _______________________________________________________ varieties of cells. C. Cells are measured in units called _______________________________________________________ . D. A micrometer equals _________________________________________________________________ . E. A human egg cell is about ____________________________________________________ in diameter. G. Cells have different, distinctive shapes that make possible their ________________________________ II. A Composite Cell A. Introduction 1. It is not possible to describe a typical cell because ___________________________________ . 2. A composite cell includes ______________________________________________________ . 3. The three major parts of a cell are ________________________________________________ 4. The nucleus is enclosed by______________________________________________________ . 5. The nucleus contains __________________________________________________________ . 6. The cytoplasm is composed of specialized structures called ________________ that are suspended in a liquid called _____________. 7. The cytoplasm surrounds the nucleus and is contained by the . B. Cell Membrane 1. General Characteristics a. The cell membrane controls ______________________________________________ . b. The cell membrane is called selectively permeable because c. Signal transduction is ___________________________________________________ . 2. Membrane Structure a. The cell membrane is mainly composed of __________________________________ b. The cell membrane has a double layer of ___________________________________ . c. The surfaces of the cell membrane are formed by _____________________________ d. The interior of the cell membrane is formed by_______________________________ e. The phospholipid bilayer is permeable to ___________________________________ f. The phospholipid bilayer is not permeable to ________________________________ g. ________________________________________ help to stabilize the cell membrane. h. Five types of membrane proteins are _______________________________________ i. Receptor proteins function to _____________________________________________ . j. Integral proteins function to ______________________________________________ k. Enzymes of the membrane function in _____________________________________ . l. Cellular adhesion molecules function to _____________________________________ . m. Cell surface glycoproteins function to _____________________________________ . 3-1 3. Cellular Adhesion Molecules a. Two examples of CAMs are _____________________________________________ . b. Selectin functions to ___________________________________________________ . c. Integrin functions to ____________________________________________________ C. Cytoplasm 1. The cytoskeleton is ___________________________________________________________ . 2. Ribosomes are composed of ____________________________________________________ . 3. Ribosomes are the sites of ______________________________________________________ . 4. Unlike many of the other organelles, ribosomes are not reactions 5. Two places ribosomes are found are ______________________________________________ . 6. The structure of endoplasmic reticulum is __________________________________________ 7. The function of endoplasmic reticulum is __________________________________________ 8. Rough endoplasmic reticulum is studded with ______________________________________ . 9. Proteins move from the ER to the ________________________________________________ . 10. Smooth endoplasmic reticulum is _______________________________________________ . 11. SER contains enzymes that ____________________________________________________ . 12. Vesicles are ________________________________________________________________ . 13. Vesicles are formed by ________________________________________________________ 14. Vesicles function to __________________________________________________________ . 15. Vesicle trafficking is _________________________________________________________ . 16. The structure of the Golgi apparatus is ___________________________________________ 17. The Golgi apparatus functions to ________________________________________________ 18. The structure of mitochondria is ________________________________________________ 19. The two layers of a mitochondrion are____________________________________________ 20. Cristae are _________________________________________________________________ . 21. Mitochondria function to ______________________________________________________ 22. Lysosomes function to ________________________________________________________ . 23. Lysosomes contain ___________________________________________________________ . 24. Peroxisomes are most abundant in a cell of the reactions__________and _____________ . 25. Peroxisomes contain _________________________________________________________ . 26. Peroxidases function to catalyze metabolic reactions _____________ 27. Peroxisomes also contain an enzyme called_________ __________, which decomposes__________________. 28. The structure of a centrosome is a _______________ Structure composed of two _____________________. 29. A centrosome is usually located near the __________________________________________ . 30. Centrosomes function to ______________________________________________________ . 31. The structure of a cilium is ____________________________________________________ . 3-2 32. The function of cilia is ________________________________________________________ . 33. The structure of a flagellum is __________________________________________________ . 34. The function of flagella are ____________________________________________________ . 35. Microfilaments are ___________________________________________________________ . 36. Microfilaments cause _________________________________________________________ . 37. Microtubules are ____________________________________________________________ . 38. Three functions of microtubules are _____________________________________________ 39. Inclusions are _______________________________________________________________ . D. Cell Nucleus 1. The nucleus contains __________________________________________________________ . 2. Chromosomes are_____________________________________________________________ . 3. The nucleus is enclosed by______________________________________________________ . 4. Nuclear pores are _____________________________________________________________ . 5. _____________________________________________________move through nuclear pores. 6. Nucleoplasm is _______________________________________________________________ . 7. Two structures found in nucleoplasm are __________________________________________ 8. The nucleolus is composed of ___________________________________________________ . 9. The nucleolus is the site of ______________________________________________________ . 10. Chromatin is ________________________________________________________________ . III. Movements Into and Out of the Cell A. Introduction 1. The cell membrane controls _____________________________________________________ . 2. Four types of physical processes are ______________________________________________ 3. Three types of physiological mechanisms are _______________________________________ B. Diffusion 1. Diffusion is _________________________________________________________________ . 2. A concentration gradient is _____________________________________________________ . 3. Diffusional equilibrium is ______________________________________________________ . 4. Substances diffuse _________________________ with a concentration gradient. 5. Two conditions that allow a substance to diffuse across a membrane are __________________ . 6. In body cells, oxygen usually diffuses_______________a body cell and carbon dioxide diffuses ____________________________________________________________________ a body cell. 7. A physiological steady state is ___________________________________________________ . 8. Five substances that cross the cell membrane through simple diffusion are _____________________________________________________________________________ . 9. The three most important factors that influence diffusion rate are________________________ _____________________________________________________________________________ . 10. In general, diffusion is more rapid over ___________________________________ distances, 3-3 ______________ concentration gradients, and at ____________________________ temperatures. C. Facilitated Diffusion 1. Facilitated diffusion requires ____________________________________________________ . 2. Substances that move across the cell membrane through facilitated diffusion are. 3. The hormone _________promotes facilitated diffusion of glucose. D. Osmosis 1. Osmosis is __________________________________________________________________ . 2. Osmotic pressure is ___________________________________________________________ . 3. Water always tends to diffuse toward solutions of____________________________________ 4. Isotonic solutions are __________________________________________________________ . 5. Hypertonic solutions are _______________________________________________________ . 6. Hypotonic solutions are ________________________________________________________ . 7. Cells _____________________________________________________in hypertonic solutions. 8. Cells _____________________________________________________ in hypotonic solutions. E. Filtration 1. The process of forcing molecules through a membrane is ______________________________ 2. Filtration is commonly used to separate ____________________________________________ . 3. In the body the force for filtration is produced by________________ F. Active Transport 1. Movement against a concentration gradient is _______________________________________ . 2. Active transport is similar to facilitated diffusion because _____________________________ 3. Substances that move across the cell membrane through active transport are ______________ . 4. Active transport requires cellular _________________________________________________ . G. Endocytosis 1. Endocytosis is the process of ____________________________________________________ . 2. Three forms of endocytosis are __________________________________________________ 3. Pinocytosis is endocytosis of ____________________________________________________ . 4. Phagocytosis is endocytosis of ___________________________________________________ . 5. Phagocytes are _______________________________________________________________ . 6. Receptor-mediated endocytosis moves________________into the cell. 7. In receptor-mediated endocytosis, a substance must bind to a ___________________________ before it can enter the cell. 8. A ligand is __________________________________________________________________ . 9. An example of a molecule that moves into a cell through receptor-mediated endocytsosis is __ . H. Exocytosis 1. Exocytosis is the reverse of _____________________________________________________ . 2. Cells secrete __________________________________________________ through exocytosis. 3. Nerve cells secrete _____________________________________________ through exocytosis. 3-4 I. Transcytosis 1. Transcytosis moves substances __________________________________________________ . 2. A virus that uses transcytosis to infect humans is ____________________________________ . IV. The Cell Cycle A. Introduction 1. The cell cycle is ______________________________________________________________ . 2. Daughter cells are ____________________________________________________________ . 3. The four stages of the cell cycle are _______________________________________________ B. Interphase 1. During interphase, a cell _______________________________________________________ . 2. The phases of interphase are ____________________________________________________ . 3. During the S phase, the cell is ___________________________________________________ . 4. During the G phases, the cell is __________________________________________________ . C. Mitosis 1. Mitosis is ___________________________________________________________________ . 2. In mitosis, the resulting daughter cells are __________________________________________ . 3. At the end of mitosis, each resulting daughter cell has _____________________ chromosomes. 4. Meiosis is ___________________________________________________________________ . 5. The division of nuclear material is called __________________________________________ . 6. The division of cytoplasm is ____________________________________________________ . 7. The four stages of mitosis are ___________________________________________________ 8. In prophase, centrioles move ____________________________________________________ . 9. In prophase, the nuclear envelope ________________________________________________ . 10. In prophase, microtubules form _________________________________________________ . 11. In prophase, chromatin condenses into ___________________________________________ . 12. Centromeres are _____________________________________________________________ . 13. In metaphase, spindle fibers attach to ____________________________________________ 14. In metaphase, the chromosomes align ____________________________________________ . 15. In anaphase, the ________________________________________ of the chromatids separate. 16. In anaphase, chromosomes move toward __________________________________________ . 17. Telophase begins when ________________________________________________________ . 18. In telophase, a nuclear envelope ________________________________________________ . 19. In telophase, chromosomes begin to _____________________________________________ . D. Cytoplasmic Division 1. Cytoplasmic division begins in________________and ends in _________________________ . 2. ___________________________________ are responsible for pinching the cytoplasm in half. 3. The resulting daughter cells have identical____________but they may vary _______________ . 3-5 V. Control of Cell Division A. Three cell types that divide continually are ________________________________________________ B. Neurons divide ______________________________________________________________________ . C. In laboratory conditions, cells divide _____________________________________________________ . D. Telomeres are ______________________________________________________________________ . E. When chromosome tips wear down, a cell ________________________________________________ . F. Two types of proteins called _______________________________________ also control cell division. G. When a cell becomes too large to obtain nutrients, it is likely to H. Two examples of external controls that influence cell division are________________ I. Hormones are _______________________________________________________________________ . J. Growth factors are ___________________________________________________________________ . K. Contact inhibition prevents ____________________________________________________________ . L. A tumor results _____________________________________________________________________ . M. A benign tumor is ___________________________________________________________________ . N. A malignant tumor is _________________________________________________________________ . O. Two types of genes that cause cancer are __________________________________________________ . P. Apoptosis is ________________________________________________________________________ . VI. Stem and Progenitor Cells A. A stem cell divides mitotically to produce ________________________________________________ B. A progenitor cell is __________________________________________________________________ . C. A neural stem cell gives rise to________________but not ____________________________________ . D. A totipotent cell can give rise to ________________________________________________________ . E. Pluripotent cells are __________________________________________________________________ . F. Cells specialize by ___________________________________________________________________ . VII. Cell Death A. ______________________ is called programmed cell death. B. Like mitosis, apoptosis is a ____________________ process. Both are a__________________ of development. Mitosis is cell _______________ while apoptosis is ____________________. 3-6