CURRICULUM VITAE
SEPIDEH AMIN-HANJANI, M.D.
Massachusetts General Hospital
Wang Ambulatory Care Center 331
15 Parkman Street
Boston, MA 02114
Tel.#: (617) 726-3776
Fax #: (617) 724-0339
Email Address: saminhanjani@partners.org
Newton Wellesley Hospital
Medical Office Building, Suite 220
2000 Washington Street
Newton, MA 02462
Tel.#: (617) 965-4717
Fax #: (617) 964-1529
TRAINING
Medical School:
Harvard Medical School, Boston
Internship:
Residency:
Chief Residency:
Department of Surgery, Massachusetts General Hospital, Boston
Neurosurgical Service, Massachusetts General Hospital, Boston
Neurosurgical Service, Massachusetts General Hospital, Boston
Clinical Appointments:
Staff Neurosurgeon, Massachusetts General Hospital, Boston
Staff Neurosurgeon, Newton-Wellesley Hospital, Newton
Academic Appointments:
Instructor in Neurosurgery, Harvard Medical School, Bsoton
BOARDS
American Board of Neurological Surgeons Primary Examination, 1998
PROFESSIONAL SOCIETIES
American Medical Association
American Association of Neurological Surgeons
Congress of Neurological Surgeons
Joint Section on Cerebrovascular Surgery
Massachusetts Medical Society
PUBLICATIONS:
ORIGINAL REPORTS:
Amin-Hanjani S, Wadsworth P: Inhibition of spindle elongation by taxol. Cell Motility and
Cytoskeleton 20:136-144, 1991.
Amin-Hanjani S, Sathi S, Scott RM: "De novo" Chiari I malformation in infants demonstrated by
sequential MRI scans: report of two cases. Pediatr Neurosurg 22:299-302, 1995.
Amin-Hanjani S, Ogilvy CS, Buonanno F, Choi IS, Metz LN: Treatment of dissecting basilar
artery aneurysm by flow reversal. Case report and review of the literature. Acta
Neurochir (Wien) 139:44-51, 1997 .
Amin-Hanjani S, Ogilvy CS, Candia GJ, Lyons S, Chapman PH: Stereotactic radiosurgery for
cavernous malformations: Kjellberg's experience with proton beam therapy in 98 cases at
the Harvard Cyclotron. Neurosurgery 42:1229-1236, 1998.
Amin-Hanjani S, Ogilvy CS, Ojemann RG, Crowell RM, : Risks of surgical management for
cavernous malformations of the central nervous system. Neurosurgery 42:1220-1227,
1998.
Amin-Hanjani S, Robertson R, Arginteanu MS, Scott RM. Familial intracranial arteriovenous
malformations. Case report and review of the literature. Pediatr Neurosurg 29:208-213,
1998.
Amin-Hanjani S, Schwartz RB, Sathi S, Steig PE: Hypertensive encephalopathy as a
complication of hyperdynamic therapy for vasospasm: report of two cases. Neurosurgery
44:1113-1116, 1999.
Amin-Hanjani S, Ogilvy CS: Overall surgical results of occult vascular malformations.
Neurosurgery Clin N Am 10: 475-483, 1999.
Kang SJ, Wang S, Hara H, Peterson EP, Namura S, Amin-Hanjani S, Huang Z, Srinivasan A,
Tomaselli KJ, Thornberry NA, Moskowitz MA: Dual role of caspase –11 in mediating
activation of caspase-1 and caspase-3 under pathological conditions. J Cell Bio, 149:613622, 2000.
Laufs U, Endres M, Stagliano N, Amin-Hanjani S, Chui DS, Yang SX, Simoncini T, Yamada M,
Rabkin E, Allen PG, Huang PL, Bohm M, Schoen FJ, Moskowitz MA, Liao JK:
Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest,
106:15-24, 2000.
Amin-Hanjani S, Stagliano N, Yamada M, Huang P, Liao JK, Moskowitz MA: Mevastatin, an
HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial
nitric oxide synthase in mice. Stroke, 32:980-985, 2001.
Barker FG II, Amin-Hanjani S, Butler WE, Lyons S, Ojemann RG, Chapman PH, Ogilvy CS:
Temporal clustering of hemorrhages from untreated cavernousmalformations of the
central nervous system. Neurosurgery, 49:15-25, 2001
CHAPTERS:
Amin-Hanjani S, Pirl W, Black PMcL: Hydrocephalus and disorders of cerebrospinal fluid flow,
in Samuels M, Feske S (eds): Office Practice ofNeurology. Churchill Livingstone, 1996,
pp138-143.
Amin-Hanjani S, Harsh GR IV: Unusual malignancies of the cerebral hemispheres, in Kaye AH,
Black PMcL (eds): Operative Neurosurgery. Churchill Livingstone, 2000, pp 481-491.
Amin-Hanjani S, Ogilvy CS: Indications and techniques for emergent carotid exploration, in
Loftus CM, Kresowik TF (eds):Carotid Artery Surgery. Thieme, 2000, pp303-313.
Amin-Hanjani S, Ojemann RG, Crowell RM, Ogilvy CS: Surgical management of cavernous
angiomas of the nervous system. Schmidek H (ed): Operative neurosurgical techniques:
Schmidek and Sweet, WB Saunders, 2000.
Amin-Hanjani S, Chapman PH: Cerebrospinal fluid and its abnormalities, in Encyclopedia of
Life Sciences, Macmillan Reference Ltd, 2001 (In press)
Amin-Hanjani S, Harsh GR IV: Cerebral lymphoma, in Winn HR (ed): Youmans Neurological
Surgery, WB Saunders, 2001 (In press).
Amin-Hanjani S, Harsh GR IV: Tumors: Cerebral metastases and lymphoma, in Winn HR,
Moore AJ(eds): Contemporary International Surgical Practice, Chapman & Hall, 2001 (In
press)
ABSTRACTS:
Smyth Jr JR, Rahmani TMZ Amin-Hanjani S: Events associated with the replacement of donor
melanocytes in embryonic neural tube allografts. Abstracts of the Poultry Science
Association, July 1989.
Rahmani TMZ, Amin-Hanjani S, Smyth Jr JR: Transient feather amelanosis following
chick embryonic allografts of neural primordia. Abstracts of the Pan American Society
for Pigment Cell Research, April 1989.
Amin-Hanjani S, Ogilvy CS, Morris P, Huang-Hellinger F, Choi IS: Reversal of flow in the
basilar artery: treatment for vertebrobasilar dissecting aneurysms. AANS Annual
Meeting, April 1996.
Amin-Hanjani S, Ogilvy CS, Crowell RM, Ojemann RG: Risks of surgical management for
cavernous malformations of the nervous system. CNS Annual Meeting, November, 1996.
Amin-Hanjani S, Ogilvy CS, Candia GJ, Lyons S, Chapman PH: Stereotactic radiosurgery for
cavernous malformations: Kjellberg's experience with proton beam therapy in 98 cases at
the Harvard Cyclotron. AANS Annual Meeting, April, 1997.
Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy CS, Ojemann RG, Chapman PH: Risk
of rebleeding after first hemorrhage from cavernous malformations. CNS Annual
meeting, September, 1997.
Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy S, Loeffler J, Chapman PH:
Complication rates after radiosurgery for cavernous malformations. CNS
Annual meeting, October, 1998.
Amin-Hanjani S, Barker FG, Ogilvy CS: Does intracisternal thrombolysis prevent vasospasm
following aneurysmal subarachnoid hemorrhage? A meta-analysis. AANS Annual
Meeting, April, 1999.
Endres M, Laufs U, Stagliano NE, Amin-Hanjani S, Liao JK, Moskowitz MA: Statins upregulate
eNOS and protect from stroke by inhibition of Rho GTP-ase. Brain meeting, June 1999.
Amin-Hanjani S, Savinova OV, Hirt L, Stagliano N, Martin JE, Moskowitz MA, John SM:
Increased susceptibility to focal cerebral ischemia in mice with reduced or absent atrial
natriuretic peptide. CNS Annual meeting, November, 1999.
Amin-Hanjani S, Stagliano N, Yamada M, Liao JK, Moskowitz MA: eNOS upregulation and
infarct reduction by mevastatin, an HMG-CoA reductase inhibitor. CNS Annual Meeting,
November, 1999.
Amin-Hanjani S, Wu Y, Huang Z, Kuida K, Moskowitz MA: Infarct reduction after transient
cerebral ischemia in caspase 3 knockout mice. AANS AnnualMeeting, April, 1999.
Hirt L, Bates B, Thomas S, Amin-Hanjani S, Jaenisch R, Moskowitz MA: The effect of
endogenous NT-3 in the mouse brain during stroke. Cerebrovasc Dis 10(2):16, 2000.
ARTICLES:
Amin-Hanjani S: Cerebral cavernous malformations. Neurovascular News, Brain
Aneurysm/AVM Center of Massachusetts General Hospital, Fall, 1998.
COMMENTS/LETTERS:
Amin-Hanjani S, Ogilvy CS: Comment. Cristante L, Hermann: Radical excision of
intramedullary cavernous angiomas. Neurosurgery 43:431, 1998.
Amin-Hanjani S, Ogilvy CS: Comment. Reyns N, Assaker R, Louis E, Lejeune JP:
Intraventricular cavernomas: three cases and review of the literature. Neurosurgery
44:654, 1999.
PRESENTATIONS
Meetings:
Amin-Hanjani S, Ogilvy CS, Candia GJ, Lyons S, Chapman PH: Stereotactic
radiosurgery for cavernous malformations: Kjellberg's experience with proton beam
therapy in 98 cases at the Harvard Cyclotron. New England Neurosurgical Society,
Winter Meeting, 1996.
Amin-Hanjani S, Ogilvy CS, Crowell RM, Ojemann RG: Risks of surgical management
for cavernous malformations of the central nervous system. New England Neurosurgical
Society, Annual Meeting, 1996.
Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy CS, Chapman PH: Risk of
rebleeding after first hemorrhage from cavernous malformations: natural history and
response to proton beam therapy. New England Neurosurgical Society, Annual
Meeting, 1997.
Moayeri NN, Amin-Hanjani S, Swearingen B, Zervas NT: Surgical outcome in
acromegaly. New England Neurosurgical Society, Annual Meeting, 1997.
Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy CS, Loeffler J, Chapman PH:
Complication rates after radiosurgery for cavernous malformations. New England
Neurosurgical Society, Winter Meeting, 1998.
Amin-Hanjani S, Asahi M, Stagliano N, Thomas S, Lo EH, Liao JK, Moskowitz MA:
Inhibition of HMG CoA reductase by simvastatin reduces infarct after embolic stroke in
mice. American Academy of Neurological Surgery, Annual Meeting, 2000.
Invited talks:
Amin-Hanjani S, Ogilvy CS: Radiosurgery for cavernous malformations. Neurosurgical
Grand Rounds, Massachusetts General Hospital, February, 1996.
Amin-Hanjani S: Stereotactic radiosurgery for cavernous malformations. Cerebral
aneurysms and vascular malformations course: indications, techniques and results of
treatment, 1998 and beyond, Harvard Medical School, May, 1998.
Ojemann RG, Amin-Hanjani S, Loeffler J, Kaelin WG: CNS hemangioblastoma.
Neurosurgical Grand Rounds, Massachusetts General Hospital, March, 2000.
Ojemann RG, Amin-Hanjani S, Rabinov J, Pilch B, McKenna M: Endolymphatic sac
tumors. Neurosurgical Grand Rounds, Massachusetts General Hospital, June, 2000.