Nuts and Bolts of Bone Marrow Transplants worksheet

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Name _____________________________________________ Date ______________ Block __________
The Nuts and Bolts of Bone Marrow Transplants
Access the following link and information on Bone Marrow Transplants
on Moodle under skeletal system activities or at www.duprayap.wikispaces.com
in the skeletal system folder.
http://www.cumc.columbia.edu/dept/medicine/bonemarrow/bmtinfo.html
Complete the following.
1. What conditions have bone marrow transplants been used to treat?
2. What is bone marrow? Where is it found? What are the cellular components of bone
marrow?
3. Why are transplants necessary?
4. What treatment is required before a bone marrow transplant? Why? What are the
consequences?
5. Define the following types of bone marrow transplants:
Allogenic BMT:
Syngeneic BMT:
6. What is GVHD?
7. How is the bone marrow to be transplanted harvested?
8. How much bone marrow and blood are harvested and what % does this represent of the
total bone marrow?
9. What is a Hickman catheter and where is it inserted for the bone marrow transplant?
10. What is a Hickman catheter used for?
11. How is the bone marrow infused/transfused?
12. What is engraftment? What precautions are taken during this time?
13. What does a successful bone marrow transplant accomplish for the recipient?
14. If the bone marrow transplant is used to treat an inherited disease, does a successful bone
marrow transplant eliminate the potential of the patient passing on the genes for the
disease? Explain.
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