Name _____________________________________________ Date ______________ Block __________ The Nuts and Bolts of Bone Marrow Transplants Access the following link and information on Bone Marrow Transplants on Moodle under skeletal system activities or at www.duprayap.wikispaces.com in the skeletal system folder. http://www.cumc.columbia.edu/dept/medicine/bonemarrow/bmtinfo.html Complete the following. 1. What conditions have bone marrow transplants been used to treat? 2. What is bone marrow? Where is it found? What are the cellular components of bone marrow? 3. Why are transplants necessary? 4. What treatment is required before a bone marrow transplant? Why? What are the consequences? 5. Define the following types of bone marrow transplants: Allogenic BMT: Syngeneic BMT: 6. What is GVHD? 7. How is the bone marrow to be transplanted harvested? 8. How much bone marrow and blood are harvested and what % does this represent of the total bone marrow? 9. What is a Hickman catheter and where is it inserted for the bone marrow transplant? 10. What is a Hickman catheter used for? 11. How is the bone marrow infused/transfused? 12. What is engraftment? What precautions are taken during this time? 13. What does a successful bone marrow transplant accomplish for the recipient? 14. If the bone marrow transplant is used to treat an inherited disease, does a successful bone marrow transplant eliminate the potential of the patient passing on the genes for the disease? Explain.