Vakhtang Mshvidadze
List of Publications
Mshvildadze V.D., Dekanosidze G.E., Kemertelidze E.P., About minor glycosides from Hedera colchica.
Khimia prirodnikh soedinenii . 1992, 5, 588-589.
Mshvildadze V. Content of flavonoids in leaves from Hedera helix L. Proceedings of the Academy of
Sciences of the Georgian SSR, Chemical Series. 1992, 18, 3, 239-240.
Mshvildadze V.D., Dekanosidze G.E., Kemertelidze E.P. Hedera growing in Georgia as perspective
remedy. Scientific-practical conference of physician., 1993.Kutaisi. Georgia.
Dekanosidze G.E., Mshvildadze V.D. Triterpene glycosides of species Hedera L. Review. Rastitelnie
resursi. 1993, 29, 2, 79-89.
Mshvildadze V.D. Dekanosidze G.E., Kemertelidze E.P., Shashkov A.S. Minor glycosides from Hedera
colchica. Structure hederacolchisides AпїЅ and C. Bioorganicheskaja khimia. 1993, 19, 10, 1001-1007.
Yavitch, P. A.; Mgebrishvili, M. A.; Churadze, L. I.; Tskitishvili, N. M.; Mshvildadze, V. D.; Dekanosidze, G.
E. Determination of triterpene glycosides in Hedera colchica. Farmatsiya. 1996, 45(2), 45-47.
Mshvildadze V. Elias R. Delmas F. Favel A. Dekanosidze G. Kemertelidze E. Balansard G. Antiprotozoal
and antifungal investigation of triterpene glycosides from Hedera species. 6-th Scientific-practical
conference of phisician. 1998.Kutaisi, Georgia.
Mshvildadze V.Elias R.Delmas. F.Dekanosidze G. Kemertelidze E. Balansard G. Antiprotozoal activity of
triterpene glycosides from Hedera L. Bulletin of the Georgian Academy of Sciences., 158, 2, 1998.
Kemertelidze E. Elias R. Foure R. Debrauwer L. Dekanosidze G. Mshvildadze V. Balansard G. Chemical
investigation of biological active triterpene saponines from dera colchica. Third international
symposium on the chemistry of natural compounds. 1998, Bukhara, Uzbekistan.
Marakian H. Delmas F. Digiorgio C. Gasquet M. Azas N. Timone-Davide P. Mshvildadze V. Elias R.
Comparison of Antileishmanic activity of three glycosides from Hedera, against Leishmania
infantum(Promastigote). Congres of the Society of Parasitology of France. 1998. Marseille, France.
Delmas F.,Favel A..Mshvildadze V., Elias R., Dekanosidze G., Kemertelidze E., Balansard G. Biological
Activity of Glycosides from Hedera colchica. Saponins in Foodstuffs and Medicinal Plants. Second
International Symposium on Saponins, 6-8 September. 1999. Pulawy, Poland.
Delmas F.,Di Giorgio C., Elias R., Gasquet M.,Azas N., Mshvildadze V., Dekanosidze G., Kemertelidze E.,
Timon-David P. Antileishmanial Activity of Three Saponines Isolated from Ivy: (-hederin, (-hederin, and
hederacolchiside A` as Compared To Their Action on Mammalian Cells Cultured in vitro. Planta Medica.
66 (2000) 1-5.
Mshvildadze V.,Favel A., Delmas F., Elias R., Faure R. Dekanosidze G., Kemertelidze E., Balansard G.
Antifungal and Antiprotozoal Activities of Saponines from Hedera colchica. Die Pharmazie. 55 (2000) 4,
325-326.
Mshvildadze V., De Meo M., Dumenil G., Dekanosidze G., Kemertelidze E.,Elias R. Evaluation of the
mutagenic and antimutagenic activities of saponins from Hedera colchica K.Koch. 4 th European
congress of Ethnopharmacology. 2000. Metz, France.
Ridoux O., Di Giorgio C., Delmas F., Elias R., Mshvildadze V., Dekanosidze G., Kemertelidze E.,Balansard
G., Timon-David P. In vitro Antilieshmanial activity of three saponins isolated from Ivy, alfa-hederin,
beta-hederin, and hederacolchiside A`, in association with pentamidine and amphotericine B.
Phytotheraphy Research . 15,298-301(2001).
Mshvildadze V.,Elias R.,Faure R.,Debrauwer L.,Dekanosidze G.,Kemertelidze E., Balansard G.
Triterpenoid Saponins from Berries of Hedera colchica. Chem. Pharm. Bull. 49(6),752-754(2001).
Mshvildadze V.,Elias R.,Faure R., Sutiashvili M.,Dekanosidze G., Balansard G.
Chemical Constituents of Possible Anthihelminthic Preparation From the Leaves of Hedera colchica.
Bulletins Academy of Sciences of Georgia. V.165, N1, 2002.
18. Barthomeuf Ch., Debiton E., Mshvildadze V., Balansard G., Kemertelidze E.
In Vitro Activity of Hederacolchiside AпїЅ Against Human Carcinoma and Melanoma . Planta Medica,
2002,68(8),672-675.
19. Mirianashvili S., Chitiashvili B., Bostashvili R., Mshvildadze V., Dekanosidze G. Study of Impact of
Hedera colchica and H.pastuchowii inhabited in Georgia on sheep Helminthiasis. Problems of Agrarian
Sciences. Tbilisi, 2002.361-365
20. Suleiman H., Mshvildadze V., Gepdiremen A., Elias R. Acute and Chronic antiinflamatory Profile of
Ivy Plant, Hedera helix, in Rats. Phytomedicine. 2003,10(5), 370-374.
21. Gerkens P.,Tabatadze N., Frederich M., Mshvildadze V., Dekanosidze G.,Balansard G., Elias R.,
Angenot L., Olivier J., De Pauw-Gillet M-C. Activites cytotoxiques de Giganteosides D et E isoles de
Cephalaria Gigantea. Deuxiem Jurnees Internationales de lпїЅAFERP. 2002. Athenes, Greece.
22. Mshvildadze V., Elias R., Baghdikian B., Ollivier E., Dekanosidze G., Kemertelidze E., Balansard G.
Qualitative and quantitative HPLC of dry extracts from the leaves of Hedera colchica and
H.pastuchowii. 5th international symposium on the chemistry of natural compounds. 2003. Tashkent,
Uzbekistan.
23. N. Tabatadze, R. Elias, V. Mshvildadze, E. Ollivier, G. Balansard. Qualitative and Quantitative HPLC
Analysis of Triterpene Saponins from the Roots of Cephalaria gigantea. The Bulletin of Georgia
Academy of Sciences. 2003.168.2.278-281.
24. V.Mshvildadze, R.Elias, B.Baghdikian, E.Ollivier, G.Dekanosidze, G.Balansard. Quantitative HPLC
analysis of triterpene glycosides in dry extracts from the leaves of Hedera colchica and H.Pastuchowii.
The Bulletin of Georgia Academy of Sciences. 2004.v.169.N3.pp536-538
25. Tabatadze N.A., Mshvildadze V., Elias R., Ollivier E., Faure R., Dekanosidze G.E.,Balansard G.,
Kemertelidze E.P. A new triterpenoid glycosides from the roots of Cephalaria gigantea L. Georgian
Chemical Journal. 2003,3(2),158-160.
26. Gulcin I., Mshvildadze V., Gepdiremen A., Elias R. Antioxidant Activity of Saponins Isolated from Ivy:
(-Hederin, Hederasaponin-C, Hederacolchiside-E and Hederacolchiside F. Planta Medica.
2004.6,70,561-564.
27. Debiton E., Borel M., Communal Y., Mshvildadze V., Barthomeuf C. In addition to membrane injury,
an affinity for melanin might be involved in the high sensitivity of human melanoma cells to
hederacolchiside A1. Melanoma Research.V14(2),Apr.2004.97-105.
28. A. Gepdiremen, V. Mshvildadze, H. SпїЅleyman ,Riad Elias. Acute and Chronic Antiinflammatory
Effects of Hedera colchica in Rats. J. Ethnopharmacology. 2004. 94(1), 191-195.
29. V. Mshvildadze, R. Elias, R. Faure, L. Debrauwer, G. Dekanosidze, E. Kemertelidze and G. Balansard.
Triterpenoid Saponins from Leaves of Hedera pastuchowii. Chem.Pharm.Bull. 2004.52(12)1411-1415.
30. V.Mshvildadze, O.Kunert, G.Dekanosidze, E.Kemertelidze, E.Haslinger. Arjunolic acid derivative
glycoside from the stems of Hedera colchica. Khimia Prirodnikh Soedinenii. 2005.41(1).48-51.
31. B.Tabidze, N.Tabatadze, V.Mshvildadze, M.Sutiashvili, R.Elias, C.Canlet, G.Dekanosidze,
G.Balansard. A triterpenoid glycoside from the tubers of Cyclamen adzharicum pobed. Georgian
Chemical Journal. 2004.4(2), 157-160.
32. Gepdiremen A, Mshvildadze V, SпїЅleyman H, Elias R. Acute antiinflammatory activity of four
saponins isolated from ivy: Alpha hederin, hederasaponin-c, hederacolchiside e and hederacolchiside-f
in carrageenan-induced rat paw edema. Phytomedicine 12 (2005) 440-444.
33. A. Gepdiremen, V. Mshvildadze, K. Bakuridze and R. Elias. Effects of Leontice smirnowii tuber
monodesmosides and crude extract in carrageenan- and histamine-induced acute inflammation model
of rats. Phytomedicine. 2006.13 (9-10). 728-731.
34. 0 . GпїЅlпїЅin, V. Mshvildadze, A. Gepdiremen and R. Elias. Screening of antiradical and antioxidant
activity of monodesmosides and crude extract from Leontice smirnowii tuberпїЅ . Phytomedicine,
2006. 13. 343-351.
35. 0 . GпїЅlпїЅin, V. Mshvildadze, A. Gepdiremen and R. Elias. The Antioxidant Acitivity of a
Triterpenoid Glycoside Isolated from the berries of Hedera colchica : 3-0-(пїЅ -D-Glucopyranosil)hederagenin. Phytotherapy Research. 2006. 20(2).130-134.
36. Dominic Dufour, AndrпїЅ Pichette, Vakhtang Mshvildadze, Marie-Eve Bradette-HпїЅbert, Serge
Lavoie, AngпїЅlique Longtin, Catherine Laprise et Jean Legault Antioxidant, anti-inflammatory and
anticancer activities of methanolic extracts from Ledum groenlandicum Retzius . Journal of
Ethnopharmacology. 2007. 111(1). 22-28
37. Pichette, A., Morin, P., Mshvildadze, V., Lavoie, S. et Legault, J. A new labdane diterpene from the
stem bark of Larix laricina. Chem. Pharm. Bull. 2006 .V54.N10. 1429-32
38. M.Sutiashvili, E.Iarosh, S.Lavoie, A.Pichette, V.Mshvildadze. Triterpene glycosides from the leaves
of Akebia quinata decne., cultivated in Georgia. Georgia Chemical Journal. 2006. v6.N5.540-541.
39. T.Muzashvili, A.Skhirtladze, Ts.Sulakvelidze, M.Benidze, V.Mshvildadze, J.Legault, A.Pichette,
E.Kemertelidze. Cytotoxic Activity of Helleborus Caucasicus A.BR. Georgia Chemical Journal. 2006. 6,6.
684-686.
40.
HYPERLINK
"mailto:dominicdufour@hotmail.com"
Dufour
D,
HYPERLINK
"mailto:andre_pichette@uqac.ca" Pichette A, Mshvildadze V, BradetteпїЅHebert M-E, Girard A, Lavoie
S,
HYPERLINK "mailto:jean_legault@uqac.ca" Legault J. Isolation et identification dпїЅun composпїЅ
naturel anticancпїЅreux dans les branches de Ledum groendlandicum Retzius. 73e Congres de
lпїЅACFAS. Chicoutimi.Canada. 10-11 May. 2005.
41. Mshvildadze V, Legault J, Lavoie S, Gauthier C , пїЅPichette A. New Cytotoxic Diarylheptanoid and
Chavicol Glycosides from the Inner Bark of Betula papyrifera. Phytochemistry. 2007, 68(20), 25312536.
42. Vakhtang Mshvildadze, Jean Legault, Serge Lavoie, Andre Pichette. Anti-oxidant and antiinflamatory activities of Buds constituents of Betula papyrifera. 50th Years of the Phytochemical
Society of Europe Congress. Cambridge, UK. 11-14 April,2007. Abstract Book, P.104.
43. Pascal C. Gerkens, Rowan Dobson, Nino Tabatadze, Vakhtang Mshvildadze, Riad Elias, Olivier
J.Peulen, Olivier M.Jolois and Marie-Claire A. De Pauw-Gillet. Apoptosis and cytolysis induced by
giganteosides and hederacolchisides in HL-60 cells. Anticancer Research. 2007. 27:2529-2534.
44. M.D.Alaniya, T.I.Gigoshvili, N. Sh. Kavtaradze, Serge Lavoie, Andre Pichette and V.D.Mshvildadze.
Cyclocephalogenin and Cyclogalegigenin from Astragalus caucasicus. Chemistry of Natural Compounds.
2007. 43, 361-362.
45. N.A.Tabatadze, B.V. Tabidze, V.D.Mshvildadze, E.Elias, G.E. Dekanosidze, and G.Balansard.
Triterpene Glycosides from Clematis orientalis. Chemistry of Natural Compounds. 2007. 43, 363.
46. M.D.Alaniya, T.I. Gigoshvili, N.Sh. Kavtaradze, S. Lavoie, A.Pichette, V.D.Mshvildadze.
Cyclocephalogenin and Cyclogalegigenin from Astragalus Caucasicus. Chemistry of Natural Compounds.
2007. 43-3, 361-362.
47. M.D.Alaniya, N.Sh. Kavtaradze, V.D.Mshvildadze, S. Lavoie, A.Pichette. Coniferyl Alcohol from
Astragalus bungeanus. Chemistry of Natural Compounds. 2007. 43-6, 706-707.
48. Francois Simard, Jean Legault, Serge Lavoie, Vakhtang Mshvildadze, Andre Pichette. Isolation and
identification of cytotoxic compounds from the wood of Pinus resinova. Phytotherapy Research. 2008.
22(7), 919-922.
49. M.Getia, V.Mshvildadze, S.Lavoie, A.Pichette, J.Legault, G.Dekanosidze. Triterpene glycosides from
the roots of Phytolacca Americana. Proceedings of the Georgian national Academy of Science. 2008.
34(2), 202-205.
50. N.Tabatadze, V.Mshvildadze, G. Dekanosidze, L.Zviadadze, R.Elias, E.Ollivier, R. Faure, G.Balansard.
Triterpenoid Glycosides from the roots of Cephalaria gigantea L. Bulletin of the Georgian Academy of
Sciences. 2005. 171, 2, 296-299.
51. Lasha Mskhiladze, Jean Legault, Serge Lavoie, Vakhtang Mshvildadze, Jumber Kuchukhidze, Riad
Elias, AndrпїЅ Pichette. Cytotoxic Steroidal Saponins from the Flowers of Allium leucanthum.
Molecules. 2008. Nov 26; 13(12):2925-34.
52. Gabriel D. Mazzucchelli, Nicolas A. Cellier, Vakhtang Mshviladzade, Riad Elias, Yong-Ho Shim, David
Touboul, LoпїЅc Quinton, Alain Brunelle, Olivier LaprпїЅvote, Edwin A. De Pauw, and Marie-Claire A. De
Pauw-Gillet. Pores Formation on Cell Membranes by Hederacolchiside A1 Leads to a Rapid Release of
Proteins for Cytosolic Subproteome Analysis. Journal of Proteome Research. 2008, 7, 1683пїЅ 1692
53. Charles Gauthier, Jean Legault, Karl Girard-Lalancette, Vakhtang Mshvildadze, AndrпїЅ Pichette.
Haemolitic Activity, Cytotoxicity, and Memebrane Cell Permeabilization of Semi-Synthetic and Natural
Lupane- and Oleanane-Type Saponins Bioorganic & Medicinal Chemistry. 2009, 17(5), 2002-2008.
54. N.Tabatadze, B.Tabidze, V.Mshvildadze, R.Elias, G.Dekanosidze, G.Balansard, and E.Kemertelidze.
Triterpene glycosides from the tubers of Leontice smirnowii. Chemistry of Natural Compounds. 2009,
45(3), 453-454.
55. M.D.Alania, N.Sh. Kavtaradze, Serge Lavoie, AndrпїЅ Pichette, and V.D. Mshvildadze. Aurone from
Astragalus microcephalus stems. Chemistry of Natural Compounds. 2009, 45(3), 455-456.
56. AndrпїЅ Pichette, Azadeh Eftekhari, Patricia Georges, Serge Lavoie, Vakhtang Mshvildadze, and
Jean Legault. Cytotoxic phenolic compounds in leaf buds of Populus tremuloides. Canadian Journal of
Chemistry. 2010, 88(2), 104-110.
57. Nino Tabatadze, Sok-Siya Bun, Badri Tabidze, Vakhtang Mshvildadze, Genri Dekanosidze, Evelyne
Ollivier, Riad Elias. New triterpenoid saponins from Leontice smirnowii. Fitoterapia,пїЅ2010,
81(7),пїЅ897-901.
58. Anna Bozhadze, Vakhtang Mshvildadze, Jean Legault , Andre Pichette, Valentina Vachnadze,
Aliosha Bakuridze. Study on Cytotoxic Activity of Some Isoquinoline Alkaloids and Extracts of
Chelidonium majus L. Growing in Georgia Allergology and Immunology, 2010,пїЅ11 (2), 172-174.
59. N.Sh. Kavtaradze, M.D. Alaniya, V.D. Mshvildadze, A.V. Skhirtladze, S.Lavoie, A.Pichette. Flavonoids
from Astragalus microcephalus. Chemistry of Natural Compounds, 2011, 46(6), 971-973.
60. M.D. Alaniya, N.Sh. Kavtaradze, S.Lavoie, A.Pichette, V.D. Mshvildadze, Z.Z.Apakidze. Chemical
constituents of the aerial part of Astragalus bungeanus. Chemistry of Natural Compounds, 2011, 46(6),
1001-1003.
61. пїЅBellila, A; Tremblay, C; Pichette, A; Marzouk, B; Mshvildadze, V; Lavoie, S; Legault, J. Cytotoxic
activity of withanolides isolated from Tunisian Datura metel L. PhytochemistryпїЅ2011;72(16):2031-6.
62. Legault, J; Perron, T; Mshvildadze, V; Girard-Lalancette, K; Perron, S; Laprise, C; Sirois, P; Pichette,
A. Antioxidant and Anti-Inflammatory Activities of Quercetin 7- O-пїЅ -D-Glucopyranoside from the
Leaves of Brasenia schreberi. Journal of medicinal foodпїЅ2011;14(10):1127-34.
63. Malkhaz Getia, Margarita Gabelaia, Badri Tabidze, Vakhtang Mshvildadze, Genri Dekanosidze. For
study of triterpene saponines from Phytolacca americana. 2-nd International Conference on Organic
Chemistry. September 25-27, 2011, Tbilisi, Georgia.
64. Anna Bozhadze,Vakhtang Mshvildadze,Valentina Vachnadze, Aliosha Bakuridze. Analytical studies
of (+)-chelidonine, protopine, and l-stylopine in Chelidonium majus growing in georgia using highperformance liquid chromatography. Chemistry of Natural Compounds. 2011, Volume 47, Number
3,477-480.
65. Pehlivan Karakas F, Karakas A, Mshvildadze V, Legault J, Pichette A, Ucar Turker A. Bioassay Guided
Fractionation of Extracts of Bellis perennis L. For Their Anticancer Activity. Planta Medica, v77, August
2011, pp. 1453. Abstracts (PM216)of 59th International Congress and Annual Meeting of the Society
for Medicinal Plant and Natural Product Research. 4th-9th September 2011, Antalya, Turkey.
66. Pehlivan Karakas F, Karakas A, Mshvildadze V, Legault J, Pichette A, Ucar Turker A. Anticancer
Activity of IN Vitro and Field-Grown Leaves Extracts From Bellis perennis L. (Common Daisy). 1st
International Symposium On Secondary Metabolites. September 12-15, 2011, Denizli, Turkey.
67. F. Pehlivan Karaka_ , A. Karakas, V. Mshvildadze, F. Simard, A. UпїЅar Turker, J. Legault, A. Pichette .
Anticancer Activity of Four Different Extracts from Galega officinalis L. (Goat s Rue). ). Abstracts (P38)
1st International Symposium On Secondary Metabolites. September 12-15, 2011, Denizli, Turkey.
68. M. Getia, V.Mshvildadze, G.Dekanosidze, M.Frederich, J.Wauters, and M.Tits. Some natural
products from aerial parts of Scrophularia imerethica. ISHS International Symposium on Medicinal
Plants and Natural Products. 17-19 June 2013, Montreal, Qc, Canada.
69. Serge Lavoie, Charles Gauthier, Jean Legault, Sylvain Mercier, Vakhtang Mshvildadze and AndrГ©
Pichette. Lanostane- and cycloartane-type triterpenoids from Abies balsamea oleoresin. Beilstein
Journal of Organic Chemistry. 2013, 9, 1333–1339.
70. Laurie Caron, Annie Deslauriers, Vakhtang Mshvildadze, AndrГ© Pichette. Volatile compounds in
the foliage of balsam fir analyzed static headspace gas chromatography(HS-GC) : An example of the
spruce budworm defoliation effect in the boreal forest of Quebec, Canada. Microchemical Journal.
2013, 110, 587-590.
71. Mulkijanian K., Novikova Zn., Sulakvelidze M., Getia M., Mshvildadze V., Dekanosidze G. Yvy water
extracts as gastric ulcer preventive agents. Georgian Medical News. 2013, 11(224), 63-66.
72. Oueslati, Samia; Ksouri, Riadh; Pichette, Andre; Lavoie, Serge; Girard-Lalancette, Karl; Mshvildadze,
Vakhtang; Abdelly, Chedly; Legault, Jean. A new flavonol glycoside from the medicinal halophyte
Suaeda fruticosa. Natural Product Research. 2014, Vol. 28, No. 13, 960–966.
73. Balla Sylla, Charles Gauthier, Jean Legault, Pierre-Yves Fleury, Serge Lavoie, Vakhtang Mshvildadze,
Tamar Muzashvili, Eter Kemertelidze, André Pichette. Isolation of a New Disaccharide Nucleoside from
Helleborus caucasicus: Structure Elucidation and Total Synthesis of Hellecaucaside A and its β-Anomer.
Carbohydrate Research. 2014, 398: 80-89.
74. François Simard, Charles Gauthier, Éric Chiasson, Serge Lavoie, Vakhtang Mshvildadze, Jean Legault,
and André Pichette. Antibacterial Balsacones J–M, Hydroxycinnamoylated dihydrochalcones from
Populus balsamifera buds. Journal of Natural Products. Publication Date (Web): April 30, 2015 (Article)
DOI: 10.1021/acs.jnatprod.5b00155.