Focusing on the period before 1600, describe and analyze the cultural and economic interactions between Europe and the Western Hemisphere as a result of the Spanish and Portuguese exploration and settlement. The Europeans interacted with the Western Hemisphere both culturally by bringing religion and diseases over and by forcing them into the encomienda system, and economically by the exporting gold and goods from plantations and through the encomienda system. In the era given, the cultural and economic interactions between Europe and the Western Hemisphere include the establishment of the encomienda system and the deterioration of Mesoamerica by the conquistadors as a result of the Spanish and Portuguese exploration and settlement. The cultural and economic interactions resulted in cultural changes including the destructutroduction of Native American societies by the Spanish, and the introduction of of Catholicism into the Americas and economic changes including the introduction of the ecomienda system and the start of the slave trade in Europe and the Americas. During the 1600’s, the Spanish and Portuguese exploration and settlement let to interactions between the Europeans and the west where the conversions, catolicism, the encomienda system, and the Columbian exchange occurred. Thesis examples: Spanish and Portuguese exploration changed the western hemisphere through affecting natives and explorers through trade, greed, and religion. (a start, connect examples to culture and economics- be more specific) Before 1600, Europe and the Western Hemisphere interacted economically through the Columbian Exchange and encomiendas, and culturally through missionaries, the emergence of slavery, and intermarriage. (clear and concise) The Spanish and Portuguese had different impacts on the native Western societies: the Spanish interfered dramatically in the Indian society both culturally and economically by colonizing the lands whereas the Portuguese impacted the economy more than the culture since they mostly utilized trading ports. As a result of European exploration in the Western Hemisphere both sides received new goods with varying value, impacted the spread of Christianity and set up settlements and a social structure in the new world. (a start – interaction is the goal, like the examples)