EUROAPS Form Hospital Case Number Birth Date of the patient: Ethnics: Caucasian/Indo-Arian ; American (Latino) ;Semitic/Arab ; African; Afro American/Caribbean; Asian ; Amerindian; Polynesian and Pacific Islander Smoker: Yes ; No ; Length (In centimeters) Weight (In Kilograms) SLE: Yes ; No ; APS classical criteria: Yes ; No Diabetes (Diabetes Mellitus (I or II) excluding diabetes of pregnancy) Yes ; No Idiopathic Thrombocytopenic Purpura: Yes ; No Other auto-immune disease (AID) (Specify) Previous Thrombosis No ; Yes Date:(dd/mm/yy)………………… Type of Thrombosis Venous:; Arterial:; Chronic Pathology Other (Specify) (only chronic pathology) Previous Pregnancies Fetal Status Order of 1) Alive; 2) Stillbirth; 3) Perinatal Death; 4) Pregnancy Miscarriage; 5)Termination of Pregnancy Weeks of pregnancy Placental pathology available (TOP) 1 2 3 4 5 6 7 8 No; Yes. No; Yes. No; Yes. No; Yes. No; Yes. No; Yes. No; Yes. No; Yes. Current Pregnancy Last Menstrual Period Conception: : Spontaneous ; Artificial Insemination by husband ; Artificial Insemination by donnor ; IVF ovum homologous insemination by husband ; IVF ovum homologous insemination by donnor ; IVF ovum donnor Date of Delivery/Miscarriage Weight at start of pregnancy (Metrical)_________ Weight at end of pregnancy(Metrical)____________ Pregnancy: Single ; Twins Dichorionic ; Twins Monochorionic Multiple Previous Intrauterine Growth Restriction (IUGR): Onset before 32 weeks with Doppler alterations ; Onset after 32 weeks with Doppler alterations ; Any kind of Onset without Doppler alterations ; Unknown Hypertensive Disease of Pregnancy (HDP): Chronic Hypertension ; Preeclampsia Early Onset (Before 32 weeks); Preeclampsia Late Onset (After 32 Weeks); HELLP; Unknown. Current pregnancy occurrences Yes Yes Miscarriage (before 10th week) Arterial Thrombosis Pulmonary Fetal Loss (10 to 24 week) Arterial Thrombosis Renal Stillbirth From (24th weeks to end) Arterial Thrombosis Mesenterics Prematurity Arterial Thrombosis Extremities IUGR Early Onset (Before 32 weeks) Arterial Thrombosis Other Localitations IUGR Late Onset (After 32 weeks) Venous Thrombosis Portal-Cave Vein Abruptio Placentae Venous Thrombosis Brain Sinus Placental Haematoma Venous Thrombosis Renal Preeclampsia Early Onset (Before 32 weeks) Venous Thrombosis Pulmonary Preeclampsia Late Onset (After 32 weeks) Venous Thrombosis Ilio-femoral HELLP Venous Thrombosis Femoro-popliteal Abnormal Uterine Blood Flow Venous Thrombosis Calves Cord Blood Flow Restriction Venous Thrombosis Other Localitations Abnormal Middle Cerebral Artery Blood Flow Venous Thrombosis Suprahepatic Arterial Thrombosis Myocardial CAPS Arterial Thrombosis Brain Other (Specify) th th Other occurrences not listed: Laboratory Data Item Results Normal Values Item Urea anti-ANX-A5 IgG Creatinine* anti-ANX-A5 IgM Uric acid* anti-Prothrombin IgG AST* anti-Prothrombin IgM ALT* anti-PE IgG Haptoglobin anti-PE IgM Alcaline Phosphatase anti-Ro/La/U1RNP GGT Anti-dsDNA* LDH* Platelets* PAPPA (Before12 weeks) MPV Beta-HCG (Before12 weeks) Homocisteinèmia Gamma globulin* aPTTp/aPTTc Ratio* Compl C3* Prothrombin Time(%)* Compl C4* Fibrinogen* Compl C3PA F II Compl CH50 F VIII LA* Protein C ANAs* Protein S ANA_Pattern Antithrombin III ANA_Titter Activate Protein C Resistance AMA type 5 Mut_MTHFR C677T aCL IgG* Mut_Protromb G202010A aCL IgM* Factor V Leiden Anti-B2GPIgG* PAI-1 mutation Anti-B2GPIgM* anti-F Xa activity Anti-aPS IgG RPR/VDRL Anti-aPS IgM FTA-ABS Results Normal Values Treatment Low Dose AAS previous to pregnancy: None ; Standard Dose; Other Time of commencement___________ Time of termination___________ Low Dose AAS During Pregnancy: None ; Standard Dose ; Other Time of commencement___________ Time of termination___________ Heparine: None; Fractionated; Unfractionated; Unknown Time of commencement___________ Time of termination___________ LMWH Type: Enoxaparin; Fraxiparin; Tinzaparin ; Bemiparin Other (Specify)………………………………………………………………………………… LMWH Dose: None; Low Prophylactic; Medium Prophylactic; High Prophylactic; Therapeutic; Unknown IV Gammaglobulins : No ; Yes; Unknown Time of commencement___________ Time of termination___________ IV Gammaglobulins (Description)………………………………………………………… …………………………………………………………………………………………… ………. Progesterone : None; Oral; Vaginal; Combined Progesterone total dose per day (Specify)……………………………………………… Progesterone Time of commencement___________ Time of termination___________ (Weeks of pregnancy or exact date when possible) Prednisone Dose per day _________ Time of commencement___________ Time of termination___________ (weeks of pregnancy or exact date when possible) Hydroxychloroquine Dose per day__________ Time of commencement___________ Time of termination___________ (weeks of pregnancy or exact date when possible) Other Treatment Related to the disease (Specify) Other Treatment Related to pregnancy (Specify) Labor and Newborn Labor : Spontaneous ; Induced; Cesarean Section ; Unknown Indication for Labor induction: (Specify): Delivery: Spontaneous; Vaginally Assisted; Cesarean Section Weight of the Newborn (Metrical) Apgar First Minute: __________ Apgar Fifth Minute: __________ pH Umbilical Vein: __________ pH Umbilical Artery: __________ Anesthesia: None ; Neuroaxial; General;Unknown Newborn Status: Alive; Stillbirth; Perinatal Death; Miscarriage Intensive Neonatal Care: Yes; No; Unknown Neonatal Complications (Specify) Placenta Measurements (Metrical) Weight : Length : Width: Thickness: Infarcts: None ; <10 per cent; 10-24.9 per cent; 25-50 per cent; >50 per cent; Unknown Infarcts Localization: Central; Peripheral; Multiple; Unknown Fibrin deposits terminal villi: No; 1-19 per cent; 20-49 per cent; 50 per cent or Higher; Unknown Fibrin deposit Localization: Central/Basal; Marginal; Transmural; Subchorionic; Maternal Floor Infarct (Thickness More than 3mm); Unknown Calcifications: None; Yes; Unknown Villitis: None; VUE; Infectious Villitis; Unknown Villitis Grade: Mild; Moderate; Severe; Unknown Vasculitis with Villitis: No; Yes; Unknown Fetal Thrombotic Vasculopathy: None; Avascular villi; Villous Stromal or Vascular Karyorrexis; Both Villous Stromal and Vascular Karyorrexis; Unknown Fetal Thrombosis Vessels: None; Chord; Chorionic Plate Vessels; Stem Villi; Unknown; Decidual Vasculopathy : None; Acute Atherosis; Lack of physiologic transformation ; Chronic Perivascular Inflammation; Decidual Vascular Thrombosis; Unknown. Placental Low Flow Changes: None; Very Small villi (distal villous hyploplasia); Increased Syncytial knots; Prominent Villous stromma; Small fetal Capillaries; Unknown. Hematoma: None; Subchorionic; Intervillous; Retroplacental; Subamniotic; Marginal ; Unknown; Chorioangiosis : None; Yes, Moderate; Yes, Marked ; Unknown. Chorioamnionitis: None; Yes; Unknown Inflammatory Maternal Response Stage: Stage1 ; Stage2 ; Stage3 ; Unknown Inflammatory Maternal Response Grade: None ; Grade1; Grade2; Unknown; Inflammatory Fetal Response Stage: Stage1 ; Stage2 ; Stage 3 ; Unknown; Inflammatory Fetal Response Grade: None ; Grade1 ; Grade 2 ; Unknown; Chorioamnionitis Fetal Vascular Thrombosis: None; Chord Vessels; Chorionic Vessels; Others; Unknown Puerperium Arterial Thrombosis: Never Myocardial ; Pulmonary; Brain ; Renal; Mesenterics ; Extremities; Other; Unknown Venous Thrombosis: Never ; Cave ; Brain; Renal ; Pulmonary ; Arms ; Iliofemoral ; Femoropoplyteal ; Calves; Others ; Unknown Puerperal Hypertension: No ; Transient Hypertension ;Preeclampsia ; HELLP; Unknown Catastrophic Antiphospholipid Syndrome: No; Yes ; Hemorrhage No ; Methrorragia ;Other ;Unknown ; Infection No ; Yes ; Unknown ; Infection (Description: Type; Main agents) Idiopathic Thrombocytopenic Purpura No ; Yes. Systemic Lupus Erytematous No ; Yes SLE-like Disease No ; Yes Other Complications (Specify) Long Term Follow-up Full blown SAP: SLE-Like: No ; Yes Full blown SLE: No ; Yes; ITP: Other chronic autoimmune diseases: No ; Yes No ; Yes No ; Yes