A Novel Micro ECMO (MECMO) Circuit Decreases Bleeding and Allows for Easier Transportation Montefiore Medical Center The Childrens Hospital at Montefiore New York, NY 10467 Goals of MECMO Circuit Decrease surface area Decrease prime volume Decrease blood product requirements Minimize bleeding and thrombosis Allow for safe transport of circuit Circuit Revisions Change in oxygenator Decreased length and diameter of tubing (1/4 inch to 3/16 inch) Elimination of components without a biocompatible surface coating MECMO Setup Comparison of ECMO Circuits 72 Hour Blood Product Administration, Bleeding, Heparin Dosing, and Thrombosis Old ECMO "Micro ECMO" (n=3) (n=3) Weight (kg) 4.79 ± 2.3 5.87 ± .02 Albumin (mL/kg) 47.69 ± 11.8 7.65 ± 6.62 Red Blood Cells (mL/kg) 83.73 ± 20.18 60.24 ± 19.88 Fresh Frozen Plasma (mL/kg) 12.24 ± 3.24 3.4 ± 5.88 Platelets (mL/kg) 50.13 ± 24.09 44.99 ± 10.3 Cryoprecipitate (mL/kg) 5.14 ± 4.77 0 Total Blood Products (mL/kg) 199.18 ± 38.56 116.27 ± 32.16 Blood Loss (mL/kg) Total Heparin (units/kg) Thrombosis Requiring Circuit Change 29.08 ± 12.32 14.2 ± 3.23 251 ± 265 334 ± 291 1 1 Transportation Conclusions In patients less than 10kg there was less blood loss and decreased blood product requirements within first 72 hours of surgery. No difference in thrombosis or circuit change Console can be mounted to patient bed or pole allowing for easier transport.