Provided by:
Gastroenterology Grand Rounds
2016
GASTROENTEROLOGY GRAND ROUNDS
January 13, 2016
5:30 pm – 6:30 pm
Perelman Center for Advanced Medicine
7 South Pavilion
Conference Room A
JAY D. HORTON, MD
Professor of Medicine
Dr. Robert C. and Veronica Atkins Chair in Obesity and Diabetes Research
Chief of Digestive and Liver Diseases
Division of Gastroenterology
University of Texas Southwestern Medical Center
“New Insights into Fatty Liver Disease”
Target Audience
This program has been designed for physicians, fellows, residents, physician assistants, QI professionals, professional
nurses, advanced practice nurses in the medical specialties of internal medicine, gastroenterology and hepatology ,
pancreatology, nutrition and endoscopy
Series Educational Objectives
After completing this activity, participants should be able to:
 Disseminate new knowledge about basic, translational and clinical science of gastroenterology
 Improve systems-based care in the division through improved communication, adherence to guidelines and
continuous quality improvement
 Increase knowledge of clinical areas outside of the division that overlap with gastrointestinal care
 Discuss issues of professionalism through examples
Session Educational Objectives
After completing this activity, participants should be able to:
 Identify mechanisms to reduce SREBP-1c Expression in the liver
 Have a better understanding of metabolic alterations that lead to hepatic steatosis
Accreditation
Physicians: The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council
for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Nurses: The Hospital of the University of Pennsylvania, Department of Nursing Education, Innovation and Professional
Development is an approved provider of continuing nursing education by the PA State Nurses Association, an accredited
approver by the American Nurses Credentialing Center's Commission on Accreditation.
Designation of Credit
Physicians: The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a
maximum of 1 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of
their participation in the activity.
Nurses: Nurse participants will be awarded 1.0 contact hour.
Acknowledgement of Commercial Support* NONE
For more information, please contact
Michele K. Fitzpatrick
215-898-0154
mfitzp@upenn.edu
Check your CME online at www.penncmeonline.com
Disclosure of Relevant Financial Relationships and Unapproved Uses of Products
It is policy at the Perelman School of Medicine at the University of Pennsylvania and the Hospital of the University of
Pennsylvania, Department of Nursing Education, Innovation and Professional Development for individuals who are in a
position to control the content of an educational activity to disclose to the learners all relevant financial relationships
that they have with any commercial interest that provide products or services that may be relevant to the content of
this continuing education activity. For this purpose we consider relationships of the person involved to include financial
relationships of a spouse or partner.
The intent of this policy is to ensure that Penn CME/CNE certified activities promote quality and safety, are effective in
improving medical practice, are based on valid content, and are independent of control from commercial interests and
free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure
information was found to contain relationships that created a conflict of interest relevant to the topic of their
presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based
presentations.
The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania, Mila Kostic,
CHCP, FACEHP, Director of CME, Zalman Agus, MD, Senior peer reviewer and Patricia A. Smith, MSN, RN-BC,
Nursing professional development specialist of the HUP Department of Nursing Innovation and Development have
disclosed that they have no relevant financial relationships with any commercial interests related to the content of
this educational activity.
The following individuals have disclosed that they have no relevant financial relationships with any commercial interests
related to the content of this educational activity:
PLANNING COMMITTEE MEMBER NAME
ANIL K. RUSTGI, MD
AMANDA MASTRANGELO, RN
PRESENTER NAME
GARY FALK, MD
BRENDA APPOLO, BS, MHS, PA-C
The following individuals have reported the listed relevant financial relationships with commercial interests related to
the content of this educational activity.
PLANNING COMMITTEE MEMBER NAME NAME OF COMMERCIAL INTEREST
RELATIONSHIP
GARY LICHTENSTEIN, MD
DAVID METZ, MD
PRESENTER NAME
Jay D. Horton, MD
ABBOTT CORPORATION/ABBVIE, ELAN, HOSPIRA, MILLENIUM PHARMACEUTICALS,
ONO PHARMACEUTICALS, PFIZER PHARMACEUTICALS, SANTARUS,
SCHERING-PLOUGH CORPORATION, TAKEDA
CONSULTANT
ALAVEN, JANSSEN ORTHOBIOTECH, FERRING, PROMETHEUS LABORATORIES, INC.,
SALIX PHARMACEUTICALS, SHIRE PHARMACEUTICALS, UCB, WARNER CHILCOTTE CONSULTANT/RESEAERCH
IRONWOOD
CME PROGRAM
AAA, LEXICON
PI
NAME OF COMMERCIAL INTEREST
Merck, Aegerion Pharmaceuticals, Catabasis, Lilly
Alnylam, Pfizer, Medivation, Novortis, Sanofi
RELATIONSHIP
SAB
Consultant
Relevant financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee,
honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits
are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and
teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected
DISCLOSURE OF UNAPPROVED USES OF PRODUCTS
PRESENTER NAME
PRODUCT
INVESTIGATIONAL AND/OR OFF-LABEL USE