LECTURE THREE JENAN M .M S.C. Connective Tissue Connective T: Is the most diverse of the four tissue types with wide variety of function . forms (CT) can be considered as a glue that holds the body together. All (CT) has three main components, cells, fibers and extracellular matrix all immersed in the body fluid Functions of Connective Tissue.: Storage of energy Protection of organs Provision of structural framework for the body Connection of body tissues Connection of epithelial tissues to muscle tissues Cells of the Connective Tissue.: There are three main cells types in connective T. Fibroblasts: these important cells are the ones that lay down the extracellular matrix Macrophages: these cells are large and are derived from blood cell Mast cells: these cells communicate chemically with our blood. Other cells that may find in specific connective tissues are: Osteocytes-- only found in bone Chondrocytes-- only found in cartilage (or developing bone) Adipocytes-- only found in adipose tissue for storing fat Blood cells-- found only in blood (unless you are injured) and there are many types of blood cells. Reticulocytes-- found only in reticular connective tissue. Fiber Of Connective Tissue : Collagen Fibers : large fibers made of the protein collagen and are typically the most abundant fibers . promote tissue flexibility. Elastic Fibers : intermediate fibers made of the protein elastin . branching fibers that allow for stretch and recoil Reticular Fibers : small delicate, branched fibers that have same chemical composition of collagen. LECTURE THREE JENAN M .M S.C. Types of Connective Tissue : 1. True Connective T. a- Loose C T. 2. Support Connective T. a- cartilage b- Dense CT. b- Bone 3. Liquid Connective T.( Blood ) 1. True connective tissue : is classified depending on the amount, type, arrangement, abundance of cells, fibers and ground substance into: A-Loose connective tissue B-Dense connective tissue A- Loose connective tissue: is a very common type of CT. that supports many structures .it's usually supports epithelialT, , has the main components of CT( cells, fibers and ground substance ) 1. Areolar CT.: consists of all three types of fibers, several types of cells, and semi-fluid ground substance found in: subcutaneous layer ,mucous membranes, around blood vessels, nerves and organs , function : strength , support and elasticity 2. AdiposeT.: consists of adipocytes; appearing fat cells. They store energy in the form of triglycerides (lipids). found in: subcutaneous layer, around organs and in the yellow marrow of long bones function : supports, protects, serves as an energy reserve .hypodermis, within abdomen and breasts 3. Reticular CT.: consists of reticular fibers and reticular cells , found in : liver , spleen ,and lymph nodes . function : forms the framework ( stroma) of organs and binds together smooth muscle tissue cells. B- Dense Connective Tissue: Dense regular connective tissue . Dense irregular connective tissue. 1.Denese regular Connective Tissue.: consists of bundles of collagen fibers and fibroblasts. LECTURE THREE JENAN M .M S.C. found in: tendons , ligament . function : provide strong attachment between various structures. 2. Denese Irrgular Connective Tissue.: consists of randomly-arranged collagen fibers and a few fibroblasts. Found in: fasciae, dermis of skin, and heart valves. Function : provide strength . dermis of skin, submucosa of digestive tract.