Ch. 14 Genetics Practice Problems I. Simply Monohybrid Crosses: R = red; r = white A. Give the genotypic and phenotypic ratios of the offspring from a heterozygous organism crossed with 1. A homozygous dominant organism 2. A heterozygous organism 3. A homozygous recessive organism B. Do the same crosses as “A” but 1. Have the trait be co-dominant 2. Have the trait be incompletely dominant II. Dihybrid Crosses: R = red; r = white; T = Tall; t = short A. Give the genotypic and phenotypic ratios of the offspring from a doubly heterozygous organism crossed with 1. A doubly heterozygous organism 2. A doubly homozygous recessive organism B. Do the same crosses as “A” but have both traits be incompletely dominant III. Beyond Dihybrid Crosses A. For a AaBbCcDdEe x AaBbCcDdEe cross 1. How many different gametes can each individual produce? How big of a Punnett Square is required for this cross? 2. What are the probabilities of the following offspring from the cross? a. AaBbCcDdEe d. 1 Offspring with all dominant traits b. AABBCCDDEE e. 1 Offspring R-D-R-D-R traits c. aaBBccDDee f. 1 Offspring that have at least one dominant trait IV. Mulitple Alleles: Blood type A. What are the offspring phenotypic ratios of 1. An IAio x IBio cross? B. Combining with dihybrid cross: R+ = “+”; r- = “-“ 1. What are the offspring ratios of the following crosses a. IAIBR+r- x ioioR+rb. IAioR+R+ x IAior-rV. Epistasis: C = color; c = albino; B = black; b = brown A. What are the offspring phenotypic ratios for the following crosses 1. Two doubly heterozygous organisms 2. A doubly homozygous dominant organism crossed with a doubly homozygous recessive individual 3. A CCbb x ccBB VI. Create a Predigree for each of the following before solving for the probability A. A man who is a carrier for cystic fibrosis marries a woman with a brother with the disorder. Neither of their parents have the disorder. 1. What is the probability of them having a. A normal child b. A child with the disorder c. A daughter with the disorder d. Two sons without the disorder B. A man who is polydactyl has a brother who isn’t and his wife is normal but has a brother who is polydactyl and both of their parents are polydactyl. 1. What is the probability of them having a. A normal child b. A child that is polydactyl c. Two normal children in a row d. Two normal children of the same sex in a row I. Simply Monohybrid Crosses: R = red; r = white A. Give the genotypic and phenotypic ratios of the offspring from a heterozygous organism crossed with 1. Genotypic Ratio – 1RR:1Rr ; Phenotypic Ratio – 100% Red 2. Genotypic Ratio – 1RR:2Rr: 1rr; Phenotypic Ratio – 3Red:1White 3. Genotypic Ratio – 1Rr:1rr; Phenotypic Ratio – 1 Red:1White B. Do the same crosses as “A” but 1. Phenotypic Ratio – 1Red:1Red-White; Phenotypic Ratio – 1 Red:2 Red-White:1White; Phenotypic Ratio – 1Red-White:1White 2. Phenotypic Ratio: same as above but instead of “Red-White” the phenotype will be pink II. Dihybrid Crosses: R = red; r = white; T = Tall; t = short A. Give the genotypic and phenotypic ratios of the offspring from a doubly heterozygous organism crossed with 1. Genotypic Ratio – 1RRTT:2RRTt:1RRtt:2RrTT:4RrTt:2Rrtt:1rrTT:2rrTt:1tt Phenotypic Ratio – 9Red-Tall:3Red-Short:3White-Tall:1White-Short 2. Genotypic Ratio – 25% RrTt; 25%Rrtt: 25%rrTt; 25%rrtt B. Phenotypic Ratio: 1:2:1:2:4:2:1:2:1 for both genotypic and phenotypic ratios III. Beyond Dihybrid Crosses A. For a AaBbCcDdEe x AaBBCcDDEe cross 1. AaBbCcDdEe = 25 = 32; AaBbCcDdEe = 25 = 32; Punnett Square = 32 x 32 = a lot = 32 2 2. What are the probabilities of the following offspring from the cross? a. 1/32 d. 243/1024 b. 1/1024 e. 9/1024 c. 1/1024 f. 1023/1024 IV. Mulitple Alleles: Blood type A. What are the offspring phenotypic ratios of 1. 1AB:1B:1A:1O B. Combining with dihybrid cross: R+ = “+”; r- = “-“ 1. What are the offspring ratios of the following crosses a. 3A+:1A-:3B+:1Bb. 3A+:1O+ V. Epistasis: C = color; c = albino; B = black; b = brown A. What are the offspring phenotypic ratios for the following crosses 1. 9 Black: 3 Brown: 4 Albinos 2. 100% Black 3. 100% Black VI. Create a Predigree for each of the following before solving for the probability A. A man who is a carrier for cystic fibrosis marries a woman with a brother with the disorder. Neither of their parents have the disorder. 1. What is the probability of them having a. 5/6 b. 1/6 c. 1/12 d. 25/144 B. A man who is polydactyl has a brother who isn’t and his wife is normal but has a brother who is polydactyl and both of their parents are polydactyl. 1. What is the probability of them having a. 1/3 b. 2/3 c. 1/9 d. 1/18