Option C - Biochemistry
Class 1&2: Proteins and Enzymes
Use the videos to help you answer questions:
1. Label the 4 levels of protein structure; and indicate the significance of each level
http://www.youtube.com/watch?v=lijQ3a8yUYQ
http://www.youtube.com/watch?v=VxWKFkzcXjE
http://www.youtube.com/watch?v=Oz2x_yxPXww&feature=related
http://www.youtube.com/watch?v=T500B5yTy58
2. Fill in the blanks:

The ??? (how many) different amino acids vary in their R groups; some R groups are non-polar, others are polar.

Polar amino acids have ……………………….that carry either a (+) or a (-) charge.

Polar amino acids are ……………………….and non-polar amino acids are ……………………………

Hydrophobic R-groups stay close together in …………………………………………..

Proteins with a lot of polar amino acids are …………………………. in water

The hydrophilic and hydrophobic properties of amino acids cause proteins to ……………………………...
3. How do fibrous and globular proteins differ?
http://www.youtube.com/watch?v=wM2LWCTWlrE
http://www.youtube.com/watch?v=eUS6CEn4GSA&feature=related
Fibrous Protein
Globular Protein
Shape
Reason for shape
Example
4. Name four proteins and give their functions
http://www.youtube.com/watch?v=g9G0zzdQx-M&feature=related
Protein
Function
5. Learn this information and then explain it to your teacher:
Type of Protein
Significance of polar/non-polar amino acids
Membrane proteins
firmly anchored in the phospholipid bilayer because they have two polar ends and a nonpolar center. One end of a membrane protein contacts the watery extracellular fluid and the
other end extends to the watery cytoplasm. The non-polar center remains inside the
membrane because it is hydrophobic.
Protein channels
facilitate the passage of polar molecules across cellular membranes because the polar amino
acids line the inside of the channel and non-polar amino acids line the outside.
Globular proteins
globular shape of enzymes and hormones results mainly from from the watery surrounding
interacting with the polar R-groups of the amino acids. The hydrophobic amino acids are
pushed inward. In enzymes, the active site has non-polar regions so that it can face outward.
6. State what is meant by the term metabolism:
http://www.youtube.com/watch?v=xPG9DNwjiRo&feature=PlayList&p=EB14B5F2C61E59CC&playnext=1&index=12
7. Describe the induced fit model to your teacher:
http://www.youtube.com/watch?v=CZD5xsOKres&feature=related
http://www.youtube.com/watch?v=MpcnkBE6FS0
8. Explain the difference between competitive & non-competitive inhibitors
http://www.youtube.com/watch?v=PILzvT3spCQ&feature=related
9. Explain end-product inhibition
:
http://www.youtube.com/watch?v=rHDp4wJ1U0w&feature=related
10. Explain to your teacher what is shown in these diagrams:
http://www.youtube.com/watch?v=VbIaK6PLrRM&feature=related
http://www.youtube.com/watch?v=5xJnYzLjPIs
11. Complete the crossword without looking at your notes:
Protein and Enzyme Crossword Activity