Frontiers in Transplantation 2015: Clinical Excellence through Innovation Day 1 - Tuesday, 1 September – Roben’s Suite, Guy’s Hospital 08.50 – 09.00 Introduction - Anthony Dorling & Giovanna Lombardi 09.00 – 09.40 Innate Immunity– Claudia Kemper 09.40 – 10.20 Allorecognition – Lesley Smyth 10.20 – 11.00 Tolerance in Transplantation – Giovanna Lombardi 11.00 – 11.30 Coffee 11.30 – 12.10 Antibody-mediated rejection – what happens when antibody binds endothelium? – Anthony Dorling 12.10 – 12.50 Antibody-incompatible (ABOi/HLAi) transplantation – Nizam Mamode 12.50 – 13.45 Lunch 13.45 – 14.30 Ischaemia-Reperfusion Injury – Martin Drage 14.30 – 15.15 Cytotopic Inhibition of innate immunity – development of targeted anticomplement and anticoagulant agents – Richard Smith 15.15 – 15.45 Coffee 15.45 – 16.30 Evaluation of Mirococept in Ischemia Reperfusion Injury of Renal Allograft –Phase IIb (EMPIRIKAL) Trial – Martin Drage 16:30 – 17:30 Wine and Cheese reception, with posters showcasing KCL Translational Research Day 2 - Wednesday, 2 September – Roben’s Suite, Guy’s Hospital 9.00 – 9.40 Importance of B cells in Transplantation – data from animal models – Chris Callaghan 9.40 – 10.20 Studies of cell-mediated immunity in chronic antibody-mediated rejection – Kin Yee Shiu 10.20 – 11.00 King’s trials in chronic rejection – Anthony Dorling 11.20 – 12.00 Immunoregulation – renal – Maria Hernandez-Fuentes 12.00 – 12.40 Immunoregulation – liver – Alberto Sanchez-Fueyo 12.40 – 13.20 Lunch 13.20 – 14.00 Immunoregulation – autoimmunity – Timothy Tree 14.00 – 14.45 Cell Therapy in Renal and Liver Transplantation – David Game and Niloufar Safinia 14.45 – 15.15 Coffee 15.15 – 16.00 Commercialising cell based therapies: The Cell Therapy Catapult Natalie Mount 16.00 – 17.00 Guest Speaker – “Tolerance in ABO-incompatible Transplantation” – Lori West 17.00 Close