Osteoarthritis Wear and Tear (Level II) PATIENT PRESENTATION Chief Complaint "My joints are killing me; I need something else for this pain." HPI Donald Abernathy is a 73-year-old man who presents to the Ambulatory Care Clinic for his regular follow-up appointment complaining of increasing pain in his lower back, hips, and right knee. Six months ago, the patient was started on acetaminophen 500 mg tablets, two tablets four times daily, and has been taking more than prescribed over the last few weeks. (He admits to taking three 500 mg tablets four times daily.) The patient is in clinic today complaining that this increased dose has not been working, and that he has been in moderate to severe pain for the last 3–4 weeks. He has been adherent to all other drug therapies. The patient is a veteran who served in the Korean conflict and worked in a factory for 35 years after his time in the military. His factory job often puts strain on his back and legs due to heavy lifting. Since retiring 15 years ago, the patient states that he has put on excess weight and developed many medical problems that are frustrating him. PMH OA x 18 years Obesity x 15 years Type 2 DM x 5 years Hyperlipidemia x 5 years HTN x 10 years BPH x 4 years PSH Appendectomy 27 years ago FH Mother died at 81 of CVA; father died at age 75 secondary to pancreatic cancer; no siblings SH Retired; receives all medications from the VA; occasional alcohol, no tobacco or illicit drug use Married; lives with wife at home; has one daughter who is a registered nurse Meds Lisinopril 10 mg po Q AM Metformin 500 mg po BID Acetaminophen 500 mg po 2 tablets four times daily Amitriptyline 25 mg po at bedtime for sleep Loratadine 10 mg po PRN Terazosin 2 mg po at bedtime All Sulfa—hives Egg products ROS Positive for pain and stiffness in right knee; low back pain with "shooting pains" radiating to the buttocks and groin area; "deep, boring" pain originating in the right pretibial area and extending distally to the right ankle and toes. Negative for headache, neck stiffness, joint swelling, or erythema; no SOB or palpitations; has been experiencing urinary hesitancy and occasional constipation; no diarrhea, no tarry stools. Fingerstick blood glucose concentrations have been running in the low 140s (he checks them once to twice per week). No blurred vision. Physical Examination GEN Well-developed, obese, Caucasian male slightly uncomfortable, but otherwise in NAD VS BP 148/88, P 84, RR 16, T 37.1°C; Wt 225 lb, Ht 5'11''. No orthostatic changes. SKIN Warm, dry; LE—shiny, somewhat discolored areas on the pretibial area bilaterally, consistent with venous stasis dermatitis HEENT NC/AT; PERRLA; funduscopic exam reveals sharp disks; mild AV nicking, but no hemorrhages or exudates; no scleral icterus; TMs intact; mucous membranes moist; poor dentition with gingival erythema; no lateral deviation of tongue; no pharyngeal edema or erythema. NECK/LYMPH NODES Supple; no thyromegaly or lymphadenopathy; no carotid bruits LUNGS CTA CV Distant heart sounds, Normal S1 and S2; PMI at 5th ICS/MCL; RRR; no MRG; no JVD or HJR ABD Obese, soft, nontender; no guarding; (+) BS; unable to assess liver size upon palpation GENIT/RECT Prostate gland slightly enlarged; normal sphincter tone; guaiac (–) stool in rectal vault MS/EXT Back pain radiating to right buttock with straight leg raising at 60°; right hip pain with flexion >90° and with internal and external rotation >45°; both hips tender to palpation; right knee (+) crepitus; right ankle with full ROM, no swelling or edema. NEURO Oriented x 3; normal affect; appears at times to alternate between apathy and anger/frustration; CN II–XII intact; DTRs equal bilaterally except for slightly diminished Achilles reflexes bilaterally; no focal deficits; gait impaired secondary to hip and knee pain. Slightly decreased sensation to pinprick and vibration on the distal half of right foot. Babinski's downgoing. Labs Na 135 mEq/L Hgb 12.8 g/dL AST 38 IU/L Ca 11.2 mg/dL K 4.7 mEq/L Hct 36.7% Alk Phos 96 IU/L Phos 4.5 mg/dL Cl 98 mEq/L WBC 4.5 x 103/mm3 T. prot 7.4 g/dL T. chol 206 mg/dL CO2 26 mEq/L Plt 286 x 103/mm3 HDL chol 33 mg/dL BUN 15 mg/dL MCV 85.3 m3 Alb 4.4 g/dL Uric acid 7.2 mg/dL LDL chol 137 mg/dL SCr 1.6 mg/dL MCH 28.4 pg ESR 18 mm/h TG 184 mg/dL Glu 248 mg/dL MCHC 34.5 g/dL CRP 0.2 mg/dL A1C 8.1% UA SG 1.011; pH 6.5; WBC (–), RBC (–), leukocyte esterase (–), nitrite (–), 1+ protein. Microscopic examination reveals 2 to 5 epithelial cells/hpf and no bacteria. X-Rays Lumbar spine: advanced degenerative changes at L3-4 and at L4-5. Right hip: moderate degenerative changes with some spurring of the femoral head and slight decrease in joint space. Right knee: moderate degenerative changes. No effusion.