MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Course Code: 200032001
TOPIC XXII: MOLECULAR GENETICS - RNA and Protein Synthesis
Pacing
Date
Traditional 5 days
Block
ESSENTIAL CONTENT
A. RNA Synthesis: Transcription (16.3, 16.5)
1. Role in the cell
2. Comparing RNA and DNA
3. Functions of RNA (types)
4. Promoters
5. Editing
6. Codons (mRNA; Start and Stop)
B. Protein Synthesis: Translation (16.5)
1. Ribosomes (rRNA; “P” and “A” sites)
2. Amino Acids (tRNA; Anticodon)
3. Codon table
4. Translation
5. Gene Expression
C. Types of Mutations: (16.4)
1. Types
a. Point
b. Frameshift
c. Chromosomal
2. Effects
a. Harmful(16.8)
b. Beneficial
c. Variation
d. Neutral
Division of Academics – Department of Science
Third Nine Weeks
OBJECTIVES
 Summarize the process of transcription.
 Identify the different types of RNA (mRNA, tRNA, and
rRNA) and explain the structure and function of each. **
 Demonstrate how specific code sequences are
translated into traits through protein synthesis.
 Trace the information flow from DNA to a protein.
 Identify the different types of codons in a mRNA
sequence & describe their purpose
 Students will explain the basic processes of transcription
and/or translation, and their roles in the expression of
genes.
 Describe how amino acids are coded.
 Identify that certain chromosomal mutations can lead to
human disorders such as sickle-cell disease.
 List possible mutagens and distinguish between
chemical and physical mutagens.
 Distinguish among the cellular processes of DNA
replication, transcription, and translation (ALD)
 Students will explain how gene and chromosomal
mutations may or may not result in a phenotypic change.
 Relate that mutation and genetic recombination
increase genetic variation. (ALD)
 Describe the structures of proteins and amino acids.
Explain the functions of proteins in living organisms.
 Identify some reactions that amino acids undergo. Relate
the structure and function of enzymes.
 All Mathematics and Language Arts benchmarks
must be incorporated into the instruction throughout
the year, where applicable.
2.5 days
03-31-16 to 04-07-16
03-31-16 to 04-07-16
INSTRUCTIONAL TOOLS
Core Text Book: Ch.13
Vocabulary:
DNA, RNA, Transcription, Messenger RNA, Ribosomal
RNA, Transfer RNA, Translation Codon, Anticodon,
Ribosome, Amino Acid, Polypeptide, Protein, Nucleotide,
Helix, Base pairing, Hydrogen bonding , Peptide Bond,
RNA splicing, RNA polymerase
Technology:
1. HHMI: Translation (Basic Detail)
2. Interactive Art: Transcription and Translation
3. Art in Motion: RNA Processing
4. Art Review: Point Mutations
5. Data Analysis: Complicated Operon
6. DNA tube: Detailed Explanation of mRNA Translation
7. NOVA: Cracking the Code of Life
8. Bozeman Podcast: Mutations
9. HippoCampus Biology: The Transcription of DNA to
RNA: Overview
10. HippoCampus Biology: Genes Encode Proteins
11. HippoCampus Biology: RNA Structure and Function
12. HippoCampus Biology: The Initiation of Transcription
13. HippoCampus Biology: Elongation, Termination and
Processing
14. HippoCampus Biology: The Transcription of DNA to
RNA: Summary
15. HippoCampus Biology: Translation, Protein Synthesis:
Overview
16. HippoCampus Biology: Decoding RNA
17. HippoCampus Biology: The Components of
Translation
18. HippoCampus Biology: The Mechanism of Translation
19. HippoCampus Biology: Translation, Protein Synthesis:
SummaryOVA: RNAi
20. Edgenuity
21. Extended Learning Modules
Page 1 of 6
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
SC.912.L.16.5
Standard:
SC.912.L.16.3
Course Code: 200032001
RNA and Protein Synthesis
Video
 Introduction: DNA Replication
 How a Specific Sequence in a DNA
Molecule is Replicated to Create an
Identical Copy of Itself
Video
 Mutation
 DNA Mutations
 Genetic Disease
Standard:
SC.912.L.16.4
Image
Video
Standard:
SC.912.L.16.5
 DNA sequence; nature of mutation
 Base pairing errors; generation of
mutations
 The Cell Cycle: Replication
 The Cell Cycle and DNA
 Base substitution mutation
 Insertion and deletion mutations
 The Central Dogma: RNA and

Transcription
 The Central Dogma: Translation and the 
Code

 What Is RNA?
 RNA Polymerase and Transcription

 Simulating the Process of Transcription
With Models

 Exceptions to the Rules of Transcription 
Closing Remarks: Transcription of DNA
to Messenger RNA
Gene Expression DNA and RNA
Review of the Processes of
Transcription and Translation of mRNA
The Standard Deviants School Biology:
RNA: Introduction
Translation
The mRNA Template
 What is the Role of RNA?
 How Does RNA Know Where to Start
Coding From a DNA Molecule?
 Introduction: Translation and Protein
Synthesis
 Degenerate Code System
 The Process of Protein Synthesis
 Translating the Message into Protein
 Cell with ribosomes highlighted
Image
Division of Academics – Department of Science
Third Nine Weeks
Page 2 of 6
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Course Code: 200032001
Standard:
SC.912.L.16.8
Video
 DNA and the Genetics of Cancer
 Defining Cancer
Standard:
SC.912.L.16.9
Video
 Gene Expression Overview
 Amino Acid and the Language of Life
Video
Standard:
SC.912.L.18.4
Audio
Standard:
HE.912.C.1.7
Video
Division of Academics – Department of Science
Third Nine Weeks
 Chromosomes, Proteins, and DNA
 Proteins and Amino Acids
 Manipulation of DNA: Using Restriction
Enzymes to Break the DNA into Smaller
 Protein Shapes Revisited
 Degenerate: More Codons Than Amino
Fragments
Acids
 Proteins, Amino Acids, and Messenger
 Enzymes and Coenzymes
RNA
 Amino Acid and the Language of Life
 Lactose Intolerance
 An Introduction to Proteins
 The Structure of the Cell: Proteins and
Enzymes
 Cystic Fibrosis
 Diabetes
 DNA and the Genetics of Cancer
 Genetic Disease


Page 3 of 6
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Course Code: 200032001
Video








Image
 Pick Your Poison: Cobra Venom Shows Therapeutic Promise
Science Behind the News: Influenza & Flu Vaccines
Georgia Tech Chemist Designs Molecules That May Stop or Slow Effects of Alzheimer's
NIH Discovers Key to Sickle Cell Cure
California Funds Stem Cell Research and Pushes for Quick Results
For Mixed Race Patients, Few Bone Marrow Donors
Animals, Injected with Human Genes, Are Possible Source of Transplantable Organs
Stem Cells Provide Hope for Heart Failure Patients
New Research May Help People Increase Their Lifespans
Division of Academics – Department of Science
Third Nine Weeks
Page 4 of 6
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I HONORS
Course Code: 200032001
SC.912.L16.3: Describe the basic process of DNA replication and how it relates to the transmission and conservation of the genetic information. ( Cognitive Complexity: Level 3:
Strategic Thinking & Complex Reasoning)
SC.912.L16.5: Explain the basic processes of transcription and translation and how they result in the expression of genes. ( Cognitive Complexity: Level 3: Strategic Thinking &
Complex Reasoning )
SCALE
LEARNING PROGRESSION

I am able to distinguish among the cellular processes of DNA replication,
transcription, and translation.
Using a given DNA nucleotide sequence, trace the pathway
from replication to transcription and translation.
Identify the corresponding protein sequence that will form
based on the original DNA nucleotide sequence and what
could occur if the original DNA sequence was changed in
any way.
Score/Step 5.0

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Create a diagram demonstrating the processes of DNA
replication, transcription and translation. Include descriptions
of each process and how they differ from one another.

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Given a diagram of the processes of DNA replication,
transcription and translation, identify the correct sequence of
each process.

I am able to choose the correct cellular process of DNA replication.
Given a diagram of the components of DNA replication,
identify the correct sequence of replication.

I am able to understand that every organism has hereditary information stored in
DNA that get passed on from one generation to another.
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES
Division of Academics – Department of Science
Third Nine Weeks
Page 5 of 6
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I HONORS
Course Code: 200032001
SC.912.L16.8: Explain the relationship between mutation, cell cycle, and uncontrolled cell growth potentially resulting in cancer. (Cognitive Complexity: Level 2: Basic Application
of Skills & Concepts)
SCALE
LEARNING PROGRESSION
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Describe how to prevent cancer by preventing mutations.

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Given a scenario of a patient just diagnosed with cancer,
trace the history of those cancer cells back to when they
were healthy.

I am able to state that mutations that affect the proteins that regulate the cell cycle
may result in uncontrolled cell growth.
Sequence the events that result in uncontrolled cell growth:
certain proteins regulate checkpoints in the cell cycle so that
it proceeds normally, a mutation occurs in the DNA of a
gene of one of these proteins, the wrong protein is made,
the checkpoint is no longer properly regulated, cells divided
without control.

I am able to recall that uncontrolled cell growth may result in cancer.
Given two difference sequences that show normal cell
division and uncontrolled cell division, describe the end
result of each sequence.

I am able to recall that cells divide in order to make more cells.
Score/Step 5.0
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
Division of Academics – Department of Science
Third Nine Weeks
Page 6 of 6