Common Instrumental Methods and the Necessary Sample Preparation Prior to Analysis Analytes Organics Volatile organics Metals Ions Amino acids, fats, carbohydrates DNA/ RNA Microstructure Sample Preparation Extraction, concentration, cleanup, derivatization Transfer to vapor phase, concentration Xtraction, concentration, speciation, derivatization Extraction, concentration, derivatization Extraction, clean up Instrument GC, HPLC, GC-MS, LC-MS Cell lysis, extraction, PCR Electrophoresis, UV-VIS, florescence Microscopy, surface spectroscopy Etching, polishing, reactive ion techniques, ion bombardments, etc GC, GC-MS AA, GFAA, ICP, ICP-MS, UV-VIS, IC IC, UV-VIS GC, HPLC, electrophoresis