Management of Diabetic Ketoacidosis in the Children’s ED Triage Level 2 if Suspicion for DKA Notify Attending Physician Place on a Monitor Maintain/Initiate NPO status Obtain Peripheral IV Access Perform bedside POCT: iStat 8, dextrose and iStat4 Order/Send Diabetes Labs Using the DKA Order Set While waiting for confirmatory labs give a 10 ml/kg bolus of normal saline If poor perfusion increase bolus to 20 ml/kg Consult Pediatric Endocrine/Diabetes If pH less < or= 7.2 notify the Pediatric Intensive Care Unit Initiate fluid management (see next page) and order Insulin 0.1 U/kg/hr (be sure to flush the line before starting the infusion, NO bolus of Insulin) At this time (Approx 1 hr LOS) obtain a second iStat 8 and iStat 4. Place a second peripheral IV. If unable, place a bifuse on primary PIV Hub. If the patient has the following criteria: pH is <7.2 Patient is age 3 or less Patient is exhibiting an alteration in mental status or has a complicating factor (secondary illness) confirm admission to the PICU and notify the attending If the glucose is <250 mg/dl start an infusion of dextrose and do not delay the initiation of insulin If patient is in stable DKA and does not exhibit the criteria to the leftAdmit to 7-2 MC nfusion of dextrose but don’t delay the initiation of insulin. Initiate 2 bag system with initiation of Insulin infusion. Utilize 2 separate Sigma pumps (1 for Insulin) (1 for IVF) Fluid Management for Diabetic Ketoacidosis Rate (ml/hr)= Maintenance plus ½ deficit (assuming 10% deficit) over 24 hrs Ideally NS with 20 mEq/L of KCL and 20 mEq/L of KPhos (In the Children’s ED, you may use NS with 40 mEq/L of KCl) and If dextrose < 250 mg/dl use D10NS with 20 mEq/L of KCL and 20 mEq/L of KPhos (In the Children’s ED, you may use D10NS or D10)