1
Supplementary Table 1. Number and rate (events per million years) of intrachromosomal
2
rearrangements (inversions) in three avian lineages in relation to the size of minimum synteny
3
block size considered.
4
Chicken-passeriform
Zebra finch
Flycatcher
ancestor
Block size
5
6
# events
rate
# events
rate
# events
rate
50 kb
203
1.69
79
1.98
61
1.53
100 kb
184
1.53
71
1.78
50
1.25
250 kb
130
1.08
48
1.20
44
1.10
1 Mb
58
0.48
19
0.48
10
0.25
7
Supplementary Table 2. The number of occurrences per kb (real numbers within
8
parentheses) of all six significantly enriched sequence motifs in the regions with highest (hot
9
regions; 792,952 bp) and lowest recombination rate (cold regions; 39,730,478 bp). Given are
10
also the significance level of enrichment (log p-value) and the enrichment level for each
11
motif.
12
Motif
13
14
# per Mb in hot
# per Mb in cold
log p-value
Enrichment
regions
regions
GATGAGATG
237 (188)
9 (360)
-144.4
26.1
GAAGGAGA
605 (480)
40 (1587)
-85.5
15.2
AATCAATC
202 (160)
16 (629)
-83.8
12.7
CCATATC
401 (318)
36 (1438)
-76.0
11.1
TCGAGG
204 (162)
34 (1338)
-36.3
6.1
GGATCC
366 (290)
78 (3112)
-22.2
4.7
15
Supplementary Table 3. Rate of inversion in different avian and mammaliana lineages.
16
Estimates from mammalian genomes are from Zhao & Bourque (2009) and were obtained
17
from the approximate proportion of inversions calculated from the total number of
18
rearrangement events reported in the original study.
19
Number of inversion/my
Flycatcher
1.5
Zebra finch
2.0
Chickenb
1.7
Human
1.0
Chimpanzee
2.1
Rhesus macaque
1.0
Great ape ancestor
1.8
Primate ancestor
1.4
Rodent ancestor
2.2
Mouse
4.5
Rat
26.2
Dogb
1.3
20
21
a
22
85 mya, Laurasiatheria-Euarchontoglires 90 mya, and mouse-rat 12 mya.
Divergence times: human-chimpanzee 6 mya, macaque-great apes 25 mya, primates-rodents
23
24
25
b
Unrooted lineage.
26
Supplementary Table 4. Mean recombination rate (cM/Mb) in distal (<15 Mb from
27
chromosome ends) and central parts (>15 Mb from chromosome ends) of chromosomes larger
28
than 50 Mb in three bird species. Data for chicken and zebra finch are from Groenen et al.
29
(2009) and Backström et al. (2010), respectively.
30
31
Part of chromosome
32
33
34
Flycatcher
Chicken
Zebra finch
Distal
3.20
3.12
2.53
Central
1.75
1.94
0.12