Endocrine System Summary Source Pancreas Adrenal medulla Adrenal cortex Thyroid Hormone Principal Effects Insulin Stimulates glycogen formation and storage; stimulates glucose oxidation; stimulates cellular uptake of amino acids and fatty acids: synthesis of protein and fat Glucagon Stimulates conversion of glycogen into glucose leading to increased blood glucose Adrenalin (Epinephrine) Stimulates elevation of blood-glucose concentration; stimulates "fight-or flight" reactions Noradrenalin (Noradrenaline) Stimulates reactions similar to those produced by adrenalin, but causes more vasoconstriction and is less effective in conversion of glycogen into glucose Glucocorticoids (corticosterone, cortisol, cortisone, etc.) Stimulate formation of carbohydrate from protein, thus elevating glycogen stores and helping maintain normal blood-sugar levels Mineralocorticoids (aldosterone, deoxycorticosterone, etc. Stimulate kidney tubules to reabsorb more sodium and water and less potassium Cortical sex hormones Stimulate development of secondary sexual characteristics, particularly those of the male Calcitonin Prevents excessive rise in blood calcium Thyroxine and triiodothyronine (together called thyroid hormone) Hypothalamus Releasing hormones Stimulate oxygen uptake and oxidate metabolism; help regulate growth and development Regulate hormone secretion by the anterior pituitary Parathyroids Parathyroid hormone (PTH) Regulates calcium-phosphate balance; acts to increase blood calcium ion level Posterior pituitary Oxytocin Stimulates contraction of uterine muscles; stimulates release of milk by mammary glands Vasopressin Stimulates increased water resorption by kidneys; stimulates constriction of blood vessels Growth hormone (STH) Stimulates growth; stimulates protein synthesis, hydrolysis of fates, and increased blood-glucose concentration Prolactin Stimulates milk secretion by mammary glands; participates in control of reproduction, osmoregulation, growth, and metabolism Thyrotropic hormone (TSH) Stimulates the thyroid Adrenocorticotropic hormone (ACTH) Stimulates the adrenal cortex Follicle stimulating hormone (FSH) Stimulates growth of ovarian follicles and of seminiferous tubules of the testes Luteinizing hormone (LH) Stimulates ovulation and conversion of follicles into corpora lutea; stimulates secretion of sex hormones by ovaries and testes Anterior pituitary Pineal Melatonin Contributes to regulation of the body’s biological clock. Testes Testosterone Stimulates development and maintenance of male accessory reproductive structures, secondary sexual characteristics, and behavior; stimulates spermatogenesis Ovaries Estrogen Stimulates development and maintenance of female accessory reproductive structures, secondary sexual characteristics, and behavior; stimulates growth of the uterine lining Progesterone Prepares uterus for embryo implantation and helps maintain pregnancy