OIE Reference Laboratory Reports Activities in 2012

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OIE Reference Laboratory Reports
Activities in 2012
Name of disease (or topic) for which you
are a designated OIE Reference
Laboratory:
Address of laboratory
Newcastle Disease
Australian Animal Health Laboratory
CSIRO Livestock Industries
Private Bag 24
Geelong VIC 3220
AUSTRALIA
Tel.:
+61 3 5227 5000
Fax:
+61 3 5227 5555
e-mail address:
[email protected]
website:
www.csiro.au
Name (including Title) of Head of
Laboratory (Responsible Official):
Dr Kurt Zuelke
Name (including Title and Position) of OIE
Reference Expert:
Paul Selleck (Retired)
Date of submission to the OIE
23 January 2013
Annual reports of OIE Reference Centres, 2012
1
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
ToR: To use, promote and disseminate diagnostic methods validated according to OIE
Standards
Test recommended by the OIE
Total number of test performed last year
Indirect diagnostic tests
Nationally
Internationally
C-ELISA NDV
Group
0
Haemagglutination inhibition (HI) test
2108
487
APMV2
0
Direct diagnostic tests
Nationally
Internationally
Taqman real-time PCR for NDV
873
60
PCR and sequencing F gene cleavage site (Pathotyping)
34
60
PCR and sequencing HA and F gene
34
60
Embryonated chicken egg culture
379
60
Immunohistochemistry for NDV
10
4
Virus Typing by HI
25
0
APMV1 (NDV)
Haemagglutination inhibition (HI) test
APMV2-9
ToR: To develop reference material in accordance with OIE requirements, and implement
and promote the application of OIE Standards.
To store and distribute to national laboratories biological reference products and any
other reagents used in the diagnosis and control of the designated pathogens or
disease.
2.
Did your laboratory produce or store imported standard reference reagents officially recognised by
the OIE or other international bodies?
Yes
3.
No
Did your laboratory supply standard reference reagents to OIE Member Countries?
Yes
Type of reagent
available
Related
diagnostic
test
Control positive
PCR reagent
Real time
PCR
No
Produced/
stored
Amount supplied
nationally
(ml, mg)
Amount supplied
internationally
(ml, mg)
Produced
??
4.5 ml
(NDV/chicken/Mya
nmar/2012)
And control
negative allantoic
fluid
Control positive
antiserum
And control
negative chicken
antiserum
2
4.5 ml
HI serology
Produced
2.7 ml
2.7 ml
Name of
recipient OIE
Member
Countries and
of institutions
Cambodia, China,
Indonesia, Lao
PDR, Myanmar,
Malaysia,
Philippines,
Thailand, Vietnam
Cambodia, China,
Indonesia, Lao
PDR, Myanmar,
Malaysia,
Philippines,
Thailand, Vietnam
Annual reports of OIE Reference Centres, 2012
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
4.
Type of reagent
available
Related
diagnostic
test
Produced/
stored
Amount supplied
nationally
(ml, mg)
Amount supplied
internationally
(ml, mg)
Name of
recipient OIE
Member
Countries and
of institutions
Network Quality
Control (low
positive control)
NDV qPCR
produced
35 ml
-
-
Did your laboratory produce diagnostic reagents other than the OIE-approved standard reference
reagents?
Yes
5.
No
Did your laboratory produce vaccines?
Yes
6.
No
Did your laboratory supply vaccines to OIE Member Countries?
Yes
No
ToR: To develop, standardise and validate, according to OIE Standards, new procedures for
diagnosis and control of the designated pathogens or diseases
7.
Did your laboratory develop new diagnostic methods validated according to OIE Standards for the
designated pathogen or disease?
x Yes
8.
No
Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen
or disease?
Yes
No
Name of the new test or diagnostic
method or vaccine developed
Description and References (Publication, website, etc.)
Real-time PCR for detection of avian
paramyxovirus 1 (APMV1) of pigeon origin
(PPMV-1)
Validation data maintained in the AAHL Quality Assurance
System shows a test with increased sensitivity over the NDV
qPCR for the detection of PPMV-1 agent in swabs
ToR: To provide diagnostic testing facilities, and, where appropriate, scientific and
technical advice on disease control measures to OIE Member Countries
9.
Did your laboratory carry out diagnostic testing for other OIE Member Countries?
Yes
No
Name of OIE
Member Country
seeking assistance
Date
(dd/mm)
No. samples received for
provision of diagnostic support
(i.e. from surveillance campaign)
No. samples received for
provision of confirmatory
diagnoses
Nepal
5 April
0
10
Myanmar
4 May
0
10
Annual reports of OIE Reference Laboratories, 2012
3
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
Indonesia
17 May
0
36
Papua New Guinea
7 March,
30
April, 4 June, 3
August,
23
November
434
0
East Timor
19 November
53
0
0
4
New Zealand
10.
Did your laboratory provide expert advice in technical consultancies on the request of an OIE
Member Country?
Yes
Name of the OIE Member Country
receiving a technical consultancy
Pakistan
No
Purpose
How the advice was
provided
Establish a Crisis Management Centre in Animal
Health, focusing on NDV, July 2012
Technical assistance
mission
ToR: To carry out and/or coordinate scientific and technical studies in collaboration with
other laboratories, centres or organisations
11.
Did your laboratory participate in international scientific studies in collaboration with OIE Member
Countries other than the own?
Yes
No
ToR: To collect, process, analyse, publish and disseminate epizootiological data relevant to
the designated pathogens or diseases
12.
Did your Laboratory collect epizootiological data relevant to international disease control?
Yes
13.
No
Did your laboratory disseminate epizootiological data that had been processed and analysed?
Yes
14.
No
What method of dissemination of information is most often used by your laboratory?
(Indicate in the appropriate box the number by category)
a)
Articles published in peer-reviewed journals: ................. 1
b)
International conferences: .............................................. 1
c)
National conferences: ...................................................... 1
d)
Other: ...............................................................................
ToR: To provide scientific and technical training for personnel from OIE Member Countries
To recommend the prescribed and alternative tests of vaccines as OIE Standards
15.
Did your laboratory provide scientific and technical training to laboratory personnel from other OIE
Member Countries?
Yes
4
No
Annual reports of OIE Reference Centres, 2012
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
a)
Technical visits: ................................................................ 6
b)
Seminars: ......................................................................... NA
c)
Hands-on training courses: .............................................. 2
d)
Internships (>1 month): ................................................... NA
Type of technical training
provided (a, b, c or d)
Country of origin of the expert(s) provided
with training
No. participants from the
corresponding country
a
Myanmar, Cambodia, Malaysia, Vietnam, Philippines
and Thailand
20
a
Malaysia
4
a
Malaysia
6
a
Malaysia
10
a
Malaysia
4
c
In Thailand, for trainees from Myanmar, Cambodia,
Malaysia, Vietnam, Philippines and Thailand
16
c
Malaysia
8
ToR: To maintain a system of quality assurance, biosafety and biosecurity relevant for the
pathogen and the disease concerned
16.
Does your laboratory have a Quality Management System certified according to an International
Standard?
Yes
No
AAHL maintains certification to AS/NZS ISO 9001:2008 for the management of its Quality Assurance
System as well as AS/NZS ISO 14001:2004 for environmental management.
17.
Is your laboratory accredited by an international accreditation body?
Yes
No
AAHL’s diagnostic operations are conducted under NATA accreditation to ISO/IEC 17025:2005. AAHL is
also accredited to ISO/IEC 17043:2010 as an international proficiency testing provider for exotic disease
agents.
Test for which your laboratory is accredited
AAHL’s scope of accreditation includes th efolowing classes of tests :
20.10 Microbiology
For companion animals, production animals, production avian species, aquatic
animals, equine species and avian species
Accreditation
body
NATA,
affiliated with
ILAC
20.11 Bacteriology
.01 Diagnostic bacteriology - incorporating identification by simple microscopy,
cultural methods of detection and identification of organisms
.03 Immunological methods of antigen detection
20.13 Other Microorganisms (including mycoplasma, rickettsia, algae)
.01 Diagnostic microbiology - incorporating identification by simple microscopy,
cultural methods of detection and identification of organisms, including inocuity testing
Annual reports of OIE Reference Laboratories, 2012
5
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
20.14 Virology
.01 Diagnostic virology - non-cultural (immunological) methods of detection
.02 Diagnostic virology - cultural methods of detection and identification of organisms,
including inocuity testing
.05 Quantitative procedures
20.15 Prions
.01 Histological identification of prion disease lesions
.02 Detection of prion protein by immunological methods (including ELISA, Western
Blots, immunohistochemistry)
.04 Detection of prion protein by bioassay
20.25 Serology of Infection
For companion animals, production animals, production avian species, equine
species and avian species
.01 Agar gel immunodiffusion tests
.02 Complement fixation tests
.03 Enzyme linked immunosorbent assays
.04 Haemagglutination inhibition
.05 Indirect fluorescent antibody tests
.06 Microscopic agglutination tests
.08 Serum agglutination tests
.09 Serum neutralisation tests
.10 Latex agglutination tests
.99 Other : Testing for rabies and rabies related lyssaviruses on human specimens
20.50 Anatomical Pathology
For companion animals, production animals, production avian species, laboratory
animals, zoo animals, wildlife, aquatic animals, equine species and avian species
20.52 Histopathology
.01 Processing of fixed specimens for histology
.04 Immunohistochemistry
.05 Histological interpretation
20.53 Electron Microscopy
.01 Transmission electron microscopy
.02 Scanning electron microscopy
.04 Immunohistochemistry electron microscopy
20.54 Necropsy
20.80 Molecular Diagnostics
.01 Identification by extraction and amplification
.02 Sequencing
.03 Genotyping
.99 Other : Testing for rabies and rabies related lyssaviruses on human specimens by
molecular techniques
18. Does your laboratory maintain a “biorisk management system” for the pathogen and the disease
concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2012, Chapter 1.1.3 or
Manual of Diagnostic Tests for Aquatic Animals 2012, Chapter 1.1.1)
Yes
No
ToR: To organise and participate in scientific meetings on behalf of the OIE
6
Annual reports of OIE Reference Centres, 2012
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
19.
Did your laboratory organise scientific meetings on behalf of the OIE?
Yes
20.
No
Did your laboratory participate in scientific meetings on behalf of the OIE?
Yes
Title of event
The 7th Asia-Pacific
Biosafety Association
Scientific Conference,
Moving Towards One
World-One Health,
No
Date
(mm/yy)
Location
Role (speaker,
presenting poster,
short
communications)
Title of the work
presented
04/12
Bali,
Indonesia.
Speaker
Emerging and Reemerging Disease
Control. Facing New
Challenges: Emerging
Pathogens & Disease
Surveillance
ToR: To establish and maintain a network with other OIE Reference Laboratories
designated for the same pathogen or disease and organise regular inter-laboratory
proficiency testing to ensure comparability of results
21.
Did your laboratory exchange information with other OIE Reference Laboratories designated for the
same pathogen or disease?
Yes
22.
Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated
for the same pathogen or disease by organising or participating in proficiency tests?
Yes
23.
No
No
Did your laboratory collaborate with other OIE Reference Laboratories for the same disease
on scientific research projects for the diagnosis or control of the pathogen of interest?
Yes
No
ToR: To organise inter-laboratory proficiency testing with laboratories other than OIE
Reference Laboratories for the same pathogens and diseases to ensure equivalence of
results.
24.
Did your laboratory organise or participate in inter-laboratory proficiency tests with
laboratories other than OIE Reference Laboratories for the same disease?
Yes
Annual reports of OIE Reference Laboratories, 2012
No
7
OIE RL for « Newcastle Disease » – « Paul Selleck » – « Australia »
Purpose for inter-laboratory test comparisons1
No. participating
laboratories
Participating OIE Member
Countries
Test laboratory sensitivity and specificity for
Newcastle disease viruses by real time PCR
7
Australia (State government
laboratories in the national laboratory
network)
Test laboratory sensitivity and specificity for
Newcastle disease viruses by real time PCR
10
Cambodia, China, Indonesia, Lao PDR,
Myanmar, Malaysia, Philippines,
Thailand, Vietnam
Test laboratory sensitivity and specificity for
detection of antibody to Newcastle disease virus by
the haemagglutination inhibition (HI) test
11
Cambodia, China, Indonesia, Lao PDR,
Myanmar, Malaysia, Philippines,
Thailand, Vietnam, and Timor Leste
ToR: To place expert consultants at the disposal of the OIE
25.
Did your laboratory place expert consultants at the disposal of the OIE?
Yes
No
Kind of consultancy
Location
Subject (facultative )
A scoping mission
Bangladesh
To create a workshop on Laboratory Networking and Proficiency
Testing for priority HPEDs in SAARC countries January 2012
OIE Training Workshop
Thailand
For OIE National Focal Points on Laboratories, August 2012
Meeting participation
Vietnam
The Fourth Laboratory Directors Forum Meeting (SE Asian region),
October 2012
Meeting participation
Vienna
Expert consultation for establishing and maintaining core facilities
for molecular test diagnosis in veterinary laboratories of developing
countries with limited resources, October 2012.
Ad hoc group participation
Paris
Biosafety and Biosecurity in Veterinary Laboratories, February and
July, 2012
Ad hoc group participation
Paris
New Approaches to Diagnosis: Applied Genomics, December 2012
Member of the OIE Biological
Standards Commission
Paris
Particpated in the BSC meeting September 2012
Publications
Conference Papers
 Shan, S. (2012). Avian paramyxovirus serotype 1 (APMV-1) in Australia. Paper presented at the
The Asian-Pacific Regional Workshop on Newcastle disease in China, Qingdao, China.
 Shan, s. (2012). Biological and molecular characterization of an avian paramyxovirus Type 1
isolated from domestic pigeons in Victoria, 2011. Paper presented at the AAVLD, Melbourne,
Vic.
Journal Article
 Serrao, E., Meers, J., Pym, R., Copland, R., Eagles, D., & Henning, J. (2012). Prevalence and
incidence of Newcastle disease and prevalence of Avian Influenza infection of scavenging village
chickens in Timor-Leste. Preventive Veterinary Medicine, 104(3-4), 301-308. doi:
10.1016/j.prevetmed.2011.12.018
1
8
See Interlaboratory test comparisons in: Laboratory Proficiency Testing at:
www.oie.int/en/our-scientific-expertise/reference-laboratories/proficiency-testing see point 1.3
Annual reports of OIE Reference Centres, 2012
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