Laboratory of medicinal plants, Phytochemistry and Experimental Pharmacology
Scientific director of the laboratory - Zuev Helena Petrovna, doctor degree holder
in Biological Sciences, Professor.
Head of Laboratory - Zibareva Larisa, doctoral degree holder in Chemical
Sciences, Senior Research Fellow.
Laboratory was found for cundacting world-class research in a wide range of
problems of modern medicine in order to obtain the original local antitumor,
antimetastatic, hemorheological, cardioprotective, nootropic, antiulcer activities
medicines on the basis of raw materials introduced plants and isolation of
biologically active compounds. Research results will be used in the treatment of
socially significant diseases.
Actual topics and future projects
● Development of science-based technologies of cultivation of medicinal plants to
produce original domestic products for the treatment and prevention of socially
significant diseases.
● Development of methods for integrated analysis of the chemical composition of
natural raw materials.
● Isolation of biologically active substances, the identification of the isolated
compounds, standardization.
● Conduct a screening study of complex extracts of natural raw materials and
isolated from them biologically active compounds in order to identify the spectrum
of pharmacological activity
 Study of anti-tumor, anti-metastatic, anti-ulcer, anti-inflammatory activity,
stress-regulating properties of plant extracts and isolated bioactive compounds,
assess of their impact on the effectiveness of cytostatic therapy of transplantable
tumor.
 Study antineuritic, anxiolytic, antidepressant and nootropic activity of the
extracts on the basis of raw materials introduced populations and isolated
biologically active compounds.
 Study of hemorheological, endothelial- neuro- and cardioprotective types of
biologically active compound.
Further plans.
Imply a continuation of preclinical research of anti-tumor, anti-metastatic, antiulcer, anti-inflammatory activity, stress-regulating properties, assessment of the
impact of plant extracts and isolated bioactive compounds on the effectiveness of
cytostatic therapy of transplantable tumor, anxiolytic, antidepressant and nootropic
activity hemorheological activity of the extracts on the basis of raw materials of
introduced populations and the isolation of biologically active compounds, the
identification of mechanism of action of biologically active substances.
Russian and foreign partners
In the area of study of biologically active substances of plant:
 N.N. Vorozhtsova Novosibirsk Institute of Organic Chemistry. (Russia)
 Ramkhamhaeng University (Thailand)
 University Pierre and Marie CURIE (France).
 Institute of Transfusion Medicine and Immunology, University of Heidelberg,
Mannheim, Germany.