CENTRAL ANIMAL HOUSE Registration No-577/CPCSEA date:31/08/2009 housing and breeding experiment Institutional Animal Ethics Committee:Chairman-Dr. B.D. Parmar, Dean, Govt. Medical College, Bhavnagar CPCSEA nominee-Dr. Sunil Kumar, Deputy director, Senior Grade Scientist Advocate-Mr. Navinbhai Rajyaguru Member-Dr. A.N. Lumbhani, Principle, Shri Samanvay institute of Pharmaceutical education and research, Botad, Bhavnagar Member-Dr.H.B.Mehta, Prof. & Head, Physiology, Govt. Medical College, Bhavnagar Member-Dr.P.R.Golakiya, Retired assistant director, Animal husbandary, Bhavnagar Member-Dr.Deepak Tiwari, Additional Professor,Psychiatry,Govt. Medical College, Bhavnagar Member secratory-Dr.C.B.Tripathi, Prof.& Head, Pharmacology Animal house staff:Veterinarian doctor-Dr. P.R.Golakiya Veterinarian technician-Mr. G.K.Ahir Laboratory technician-Miss. Jalpa Mandaviya Sweeper- Mr.Sunil Mansukhbhai Mr.Pravin Mangabhai Mr. Girjashankar Jatela Total number of animals (as on 14/02/2012) Animal species Male Female Litters Total Mice 12 22 ---- 34 Rats(Wistar) 30 42 14 86 Rats(Charles- 11 22 ---- 33 Rabbits 14 22 11 47 Guinea pigs 35 40 ---- 75 foster) 275 PUBLISHED RESEARCH WORK ON ANIMALS:1. Patel TK, Patel PB, Tripathi CB. Effect of Pantoprazole and its Interaction with Vecuronium on the Neuromuscular Junction. Indian Journal of Pharmacology, 2010; 43:36-9. 2. Patel PB, Baxi SN Patel TK, Tripathi CB,. Antitubercular effect of 8-[(4-Chloro phenyl) sulfonyl]-7-Hydroxy-4-Methyl-2H-chromen-2-One in guinea pigs. Journal of Pharmacology and Pharmacotherapeutic October-December | Volume 2 | Issue: 4, 253260,2011 3. Patel PB, Patel TK, Shah P, Baxi SN, Sharma HO, Tripathi CB. Protective Effect of Ethanolic Extract of Gymnosporia montana (Roth) Bemth. in Paracetamol-Induced Hepatotoxicity in Rats. Indian Journal of Pharmaceutical Science, 2010;72:392-96. 4. Patel PB, Patel TK, Patani S, Baxi SN, Sharma HO, Tripathi CB. Hepatotoxicity Studies of Nimesulide in Litters of Rat. National Journal of Integrated Research in Medicine, 2010;2:16-21. 5. Sanmukhani J, Anovadiya A, Tripathi CB. Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Poloniae Pharmaceutica – Drug Research.5; 2011. 6. Patel YA, Vadgama VK, Baxi SN, Tripathi CB. Evolution of Hypolipidemic Activity of Leaf Juice of Catharanthus roseus (Linn.) G. Donn. In Guinea Pigs. Acta Poloniae Pharmaceutica – Drug Research. Issue 6;2011. 7. Vadgama VK, Patel YA, Patel TK, Tripathi CB. Pharmacodynamic interaction between pantoprazole and vecuronium at neuromuscular junction. Auton Autacoid Pharmacol. 2011 Jan;31(1-2):31-5. UNDERGOING RESEARCH WORK ON ANIMALS:1. Effect of Zidovuine and Satranidazole on Neuromuscular junction and Interaction with Rocuronium In vitro by Rat Phrenic nerve Diaphragm and In vivo by Animal Models. 2. Effect of Curcumin on combination with Antiseizure drugs in Maximal Electroshock (MES) and Pentylenetetrazole (PTZ) induced seizure and on memory retention in swiss albino Mice. 3. Effect of topical nitric oxide donor(0.2% glyceryl trinatrate) on diabetic wound healing in wistar albino rats. 4. Effect of Pedalium Murex Linn. in Ethylene Glycol induced Renal Stone in Wistar Albino rat. 5. Effect of Fluoxetine and its Interaction with Rocuronium at Neuromuscular Junction 6. Evaluation of Anti-Inflammatory, Analgesic and Anti-Pyretic Activity of Pedalium Murex (Linn.) in Experimental Animals 7. Interaction of rosuvastatin and rocuronium at neuromuscular junction in sciatic nerve gastrocnemious muscle preparation in rats. 8. Effect of bryophyllum pinnatum and cow urine ark on ethylene glycol induced renal stone in wistal albino rats. 9. Evaluation of antidepressant and nootropic activity of aqueous extract of celastrus paniculatus wild and cow urine ark in animal models. 10. Effect of hypolipidemic activity of ethanolic extract of Cyprus rotundum linn. in guinea pigs. 11. A comparative analgesic, anti-inflammatory and antipyretic effect of three diclofenac congeners with diclofenac in albino rats. Pictures;-