Central Animal House - Government Medical College Bhavnagar

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CENTRAL ANIMAL HOUSE
Registration No-577/CPCSEA date:31/08/2009 housing and breeding experiment
Institutional Animal Ethics Committee:Chairman-Dr. B.D. Parmar, Dean, Govt. Medical College, Bhavnagar
CPCSEA nominee-Dr. Sunil Kumar, Deputy director, Senior Grade Scientist
Advocate-Mr. Navinbhai Rajyaguru
Member-Dr. A.N. Lumbhani, Principle, Shri Samanvay institute of Pharmaceutical education
and research, Botad, Bhavnagar
Member-Dr.H.B.Mehta, Prof. & Head, Physiology, Govt. Medical College, Bhavnagar
Member-Dr.P.R.Golakiya, Retired assistant director, Animal husbandary, Bhavnagar
Member-Dr.Deepak Tiwari, Additional Professor,Psychiatry,Govt. Medical College, Bhavnagar
Member secratory-Dr.C.B.Tripathi, Prof.& Head, Pharmacology
Animal house staff:Veterinarian doctor-Dr. P.R.Golakiya
Veterinarian technician-Mr. G.K.Ahir
Laboratory technician-Miss. Jalpa Mandaviya
Sweeper- Mr.Sunil Mansukhbhai
Mr.Pravin Mangabhai
Mr. Girjashankar Jatela
Total number of animals (as on 14/02/2012)
Animal species
Male
Female
Litters
Total
Mice
12
22
----
34
Rats(Wistar)
30
42
14
86
Rats(Charles-
11
22
----
33
Rabbits
14
22
11
47
Guinea pigs
35
40
----
75
foster)
275
PUBLISHED RESEARCH WORK ON ANIMALS:1. Patel TK, Patel PB, Tripathi CB. Effect of Pantoprazole and its Interaction with
Vecuronium on the Neuromuscular Junction. Indian Journal of Pharmacology, 2010;
43:36-9.
2. Patel PB, Baxi SN Patel TK, Tripathi CB,. Antitubercular effect of 8-[(4-Chloro phenyl)
sulfonyl]-7-Hydroxy-4-Methyl-2H-chromen-2-One
in
guinea
pigs.
Journal
of
Pharmacology and Pharmacotherapeutic October-December | Volume 2 | Issue: 4, 253260,2011
3. Patel PB, Patel TK, Shah P, Baxi SN, Sharma HO, Tripathi CB. Protective Effect of
Ethanolic Extract of Gymnosporia montana (Roth) Bemth. in Paracetamol-Induced
Hepatotoxicity in Rats. Indian Journal of Pharmaceutical Science, 2010;72:392-96.
4. Patel PB, Patel TK, Patani S, Baxi SN, Sharma HO, Tripathi CB. Hepatotoxicity Studies
of Nimesulide in Litters of Rat. National Journal of Integrated Research in Medicine,
2010;2:16-21.
5. Sanmukhani J, Anovadiya A, Tripathi CB. Evaluation of antidepressant like activity of
curcumin and its combination with fluoxetine and imipramine: an acute and chronic
study. Acta Poloniae Pharmaceutica – Drug Research.5; 2011.
6. Patel YA, Vadgama VK, Baxi SN, Tripathi CB. Evolution of Hypolipidemic Activity of
Leaf Juice of Catharanthus roseus (Linn.) G. Donn. In Guinea Pigs. Acta Poloniae
Pharmaceutica – Drug Research. Issue 6;2011.
7. Vadgama VK, Patel YA, Patel TK, Tripathi CB. Pharmacodynamic interaction between
pantoprazole and vecuronium at neuromuscular junction. Auton Autacoid Pharmacol.
2011 Jan;31(1-2):31-5.
UNDERGOING RESEARCH WORK ON ANIMALS:1. Effect of Zidovuine and Satranidazole on Neuromuscular junction and Interaction with
Rocuronium In vitro by Rat Phrenic nerve Diaphragm and In vivo by Animal Models.
2. Effect of Curcumin on combination with Antiseizure drugs in Maximal Electroshock
(MES) and Pentylenetetrazole (PTZ) induced seizure and on memory retention in swiss
albino Mice.
3. Effect of topical nitric oxide donor(0.2% glyceryl trinatrate) on diabetic wound healing in
wistar albino rats.
4. Effect of Pedalium Murex Linn. in Ethylene Glycol induced Renal Stone in Wistar
Albino rat.
5. Effect of Fluoxetine and its Interaction with Rocuronium at Neuromuscular Junction
6. Evaluation of Anti-Inflammatory, Analgesic and Anti-Pyretic Activity of Pedalium
Murex (Linn.) in Experimental Animals
7.
Interaction of rosuvastatin and rocuronium at neuromuscular junction in sciatic nerve
gastrocnemious muscle preparation in rats.
8. Effect of bryophyllum pinnatum and cow urine ark on ethylene glycol induced renal
stone in wistal albino rats.
9. Evaluation of antidepressant and nootropic activity of aqueous extract of celastrus
paniculatus wild and cow urine ark in animal models.
10. Effect of hypolipidemic activity of ethanolic extract of Cyprus rotundum linn. in guinea
pigs.
11. A comparative analgesic, anti-inflammatory and antipyretic effect of three diclofenac
congeners with diclofenac in albino rats.
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