CP Biology 2015-2016 Name ______ ____________ UNIT 1C: Biochemistry Part 1 Chapter 2: The Chemistry of Life 2.3 Carbon Compounds (Organic Chemistry) What is the difference between ORGANIC and INORGANIC chemistry? *Organic chemistry means the study of compounds that contain bonds between carbon atoms; *Inorganic chemistry is the study of all other compounds. Why is Carbon so interesting? Carbon has four valence electrons, allowing it to form bonds with many other elements such as H, P, O, S and N. One carbon atom can bond to another, giving it the ability to form chains that are almost unlimited in length. These carbon-carbon bonds can be single, double or How many bonds does a single carbon atom form to even triple covalent bonds. become stable? Chains of carbon atoms can even close up on themselves to form rings. No other element comes close to ______4_________ bonds. matching carbon's versatility. (HONC 1234) Your personal notes, summary of the lesson, and/or questions that you may have: 1 *ORGANIC COMPOUNDS: Are usually defined as compounds which contain carbon with hydrogen. (May contain additional elements such as O, N, P, K, S, Fe, Ca, Na, Cl and others.) Are produced only by living things (biotic). Range from simple to very complex. Contain strong, covalent bonds. Examples: CH4, C6H12O6, SUGARS, PROTEINS, FATS, OILS, DNA *INORGANIC COMPOUNDS: Usually defined as compounds that do not contain carbon with hydrogen. (exceptions may contain just carbon.) They often can be formed in the non-living (abiotic) environment, but : Can also be made by/found in living things. Examples: H2O, NaCl, O2, NH3, CaCO3, CO2 Identify whether each of the following compounds is organic or inorganic by placing a √ in the appropriate column. Substance Organic? Inorganic? 1. sodium chloride (table salt): NaCl 2. glucose: C6H12O6 X X 3. water: H2O X 4. heating oil: C14H30 X 5. chitin (a protein): C8H12NO5 X 6. thymine (a nitrogenous base): C5H5N2O2 X 7. sulfuric acid: H2SO4 X 8. oxygen gas: O2 X 9. ethanol: C2H5OH X 10. adenosine triphosphate (ATP): C10H16N5O13P3 X 11. carbon dioxide: CO2 X Your personal notes, summary of the lesson, and/or questions that you may have: 2 1 The General Structure of Macromolecules Many of the organic compounds produced by living things are so large that they are called *macromolecules which means giant molecules. Examples: Carbohydrates, lipids, proteins and nucleic acids. Most macromolecules are formed through a process called *polymerization in which large compounds are built by joining smaller ones together. The smaller repeating units called *monomers may be identical or different from one another. The large compounds which are formed from the joining of many monomers are called *polymers. monomer monomer dimer Two monomers joined together are called a *dimer. The exception: Lipids are not composed of monomers and polymers. Instead, they take different forms which we will discuss later in this unit. polymer dimer monomers Your personal notes, summary of the lesson, and/or questions that you may have 3 1 Four Types of Biologically Important Macromolecules What are the four major types of organic macromolecules and what are the building blocks of each type? Carbohydrates (monosaccharides) Lipids (glycerol and 3 fatty acids) Nucleic Acids (nucleotides) Proteins (amino acids) (In this unit, we will be focusing primarily on the STRUCTURE or FORM of these molecules. We will discuss their FUNCTION at appropriate points throughout the course.) Most of the foods we eat are made from living things; therefore they are composed of a variety of different organic molecules. A well-balanced diet provides not only the energy needed to fuel life processes but also the materials needed for cells to build essential molecules and cell structures. GROUP Basic Building Blocks (Monomers) Polymer Carbohydrates Monosaccharides Polysaccharide Lipids Glycerol + 3 F.A. Triglyceride Nucleic Acids Nucleotides Nucleic acids Proteins Amino Acids Polypeptide Carbohydrates Lipids Pasta, bread, fruits, grains, Foods in candy, potato which they are found Vegetable oil, olive oil, fat from animal meats, butter Nucleic Acids Proteins Found in any Nuts, animal food that meats, eggs, comes from beans, soy living things / cells Organic molecules must be digested and converted by metabolic processes into molecules organisms can use. All organisms use chemical processes to BUILD UP and BREAK DOWN organic polymers. Remember, there is a continual cycling of matter throughout all ecosystems, while energy is not recycled Your personal notes, summary of the lesson, and/or questions that you may have: 4 Synthesis and Breakdown of Macromolecules Two major chemical processes (metabolic reactions) occur to build up or break down all four types of macromolecules into larger or smaller units. *Dehydration Synthesis is the combination of smaller organic subunits by the removal of water. This chemical reaction involves removing an –H from one subunit and an –OH from the other subunit to allow the subunits to bond together. A _polymer (large molecule)___ and _water_______ are products of the reaction Dehydration Synthesis. NOTE: Water is produced as a product. *Hydrolysis is the breakdown of macromolecules into their subunits by adding water. This chemical reaction involves breaking a bond and adding an –H and an – OH to adjacent subunits so the molecules can exist separately. NOTE: Water is required as a reactant. Water is a (reactant / product) of the reaction, Hydrolysis. Smaller molecules are the (reactants / products) of the reaction, Hydrolysis. These reactions occur in both directions, depending upon the needs of the organism. Your personal notes, summary of the lesson, and/or questions that you may have: 14 1 CARBOHYDRATES Monosaccharides - small, ring-like structures are important for energy and cell structure. Sometimes called ‘hydrated’ carbons. They contain atoms of *CARBON, HYDROGEN and OXYGEN, usually in a ratio of *1: 2: 1. Carbohydrates differ in structural makeup. They range from small, monosaccharides (*simple sugars) to intermediate molecules such as disaccharides, to large polysaccharides (complex carbohydrates). *GLUCOSE *FRUCTOSE Chemical Formula – C6H12O6 Chemical Formula - C6H12O6 *Monosaccharides: single sugar molecules, the simplest (monomer) unit of carbohydrates. *GALACTOSE Chemical Formula - C6H12O6 *RIBOSE Chemical Formula – C5H10O5 *Disaccharides: a compound made by joining two monosaccharides together Examples *Sucrose - (table sugar) - made by joining Glucose and Fructose *Lactose - (milk sugar) - made by joining Galactose and Glucose Disaccharides Your personal notes, summary of the lesson, and/or questions that you may have: Isomer - molecules with the same chemical formula, BUT different structural formulas or shapes STRUCTURE LEADS TO FUNCTION!!! 5 1 *Polysaccharides: large molecules formed from many monosaccharides. Aka: complex carbohydrates CELLULOSE GLYCOGEN STARCH *What differences and/or similarities do you notice about the polysaccharides above? They are all composed / made up of monosaccharides (glucose - ring-like simple sugars), but the bonds that connect them can be arranged differently – some are straight and some are branched (bent). Your personal notes, summary of the lesson, and/or questions that you may have: 6 1 Important Polysaccharides Synthesized by Animals and Plants: Animals consume carbohydrates in food, digest them (hydrolysis) and then store the excess sugar by synthesizing glycogen. *Glycogen is a polysaccharide that many animals make to store excess sugar, sometimes referred to as "animal starch". When the level of glucose in your blood runs low, glycogen stored in the liver and muscles is broken down into glucose which is released into the blood so it can be delivered to cells. Plants produce glucose during photosynthesis and use it to synthesize starch. *Starch is a polysaccharide that plants make to store excess sugar. In addition, *Cellulose is another polyssacharide made by plants. It forms tough flexible fibers that give plants much of their strength and rigidity. Cellulose is a major component of the cell walls of plant cells. Wood and paper are made largely of cellulose! Humans generally can't digest cellulose ("fiber"), but it helps regulate the elimination of your solid wastes. Examine the picture to the right. What do starch, glycogen and cellulose have in common? 1) __all are examples of polysaccharides_____________ 2) __all are made up of glucose monomers____________ 3) __all organic…all contain only C, H, and O________ Your personal notes, summary of the lesson, and/or questions that you may have: Starch = the energy storage molecule for plants Glycogen = the energy storage molecule for animals Cellulose = the structural molecule for plant cell walls 7 1