Postdoctoral Researcher Bioactives from Aquaculture Waste School of Chemistry Ref. No: NUIG 83-12 Applications are invited from suitably qualified candidates for a 2-year fixed-term contract post of Postdoctoral Researcher based at the National University of Ireland, Galway (NUIG) to work on the Marine Functional Foods Research Initiative (Nutramara programme). Nutramara is an Irish collaborative research programme for the development of marine-based functional foods, established by the Marine Institute and the Department of Agriculture, Fisheries and Food (DAFF). It is supported by funds provided under the Strategy for Science, Technology and Innovation 2006-2013 (SSTI) and the Food Institutional Research Measure (FIRM). The Nutramara programme involves a consortium of Teagasc and five universities (NUIG, UCC, UCD, UL and UU Coleraine). The research position based at NUIG will involve close interactions with other projects, such as the Beaufort Biodiscovery Project. Job description: Aquaculture based materials remain an underutilized resource and a potential source of bioactive compounds. The main focus of the post-doctoral position is the extraction, profiling, purification, and chemical characterisation of bioactives, predominantly primary metabolites (proteins/peptides, carbohydrates and lipids) from aquaculture waste streams particularly those from the shellfish. S/he will work closely with consortium members in bioactivity profiling of the extracts. The occupant is expected to work independently as part of the NutraMara team, and will integrate into a highly interactive environment. Effective communication skills are a desirable attribute as communication across a broad range of scientific disciplines is part of the programme. The occupant will be partly involved and will build strategic linkages with other relevant research projects such as the Beaufort Biodiscovery project. The appointee will be responsible for the day-to-day activities in the laboratory, writing reports and publications and will assist supervision of junior staff members and students. Main duties and responsibilities: Collect marine materials, which will involve trips to aquaculture businesses or field stations Maintain sample details and research records for generated extracts Develop and optimize extraction methods using solvent based systems and fermentation methods Perform chemical profiling, qualitative and quantitative analysis of extracts by HPLC, LC-MS, GC-MS and other methods Fractionation/enrichment and purification of metabolites, particularly proteins and peptides Chemical characterization and structure/sequence determination of natural metabolites, particularly proteins and peptides Write reports, conduct literature reviews and curate data as required by the project management team. Seek opportunities to promote the work of the Nutramara programme, through conference and workshop presentations, and dissemination activities including publication of papers in high impact, peer reviewed journals. Take responsibility for delivery of project objectives associated with NUI Galway Assist the project management team and interact with related PhD projects at NUI Galway and the project partners in the consortium Assist the supervision of postgraduate and undergraduate students Manage or provide significant assistance to the operations of a research laboratory including maintaining laboratory equipment and materials, the disposal of waste and the ordering of supplies Provide high level of administrative and financial management support for research projects and programs including the maintenance and use of electronic and paper based information systems, data bases, websites etc Ensure that the project is carried out on time in accordance with the work programme and with reference to the appropriate health and safety guidelines and any other relevant NUI Galway policies (e.g., purchasing and procurement). Keep abreast of developments, activities and protocols in area of expertise through liaison with staff and peers, reading relevant literature and attendance at meetings and seminars; Maintain confidentiality of Intellectual Property (IP) associated with the project and liaise with the project IP committee to ensure this. Assist in the application and protection of IP by identifying potential research results of value and preparing supporting documentation as required by the IP committee and Technology Transfer Office. Skills required: A PhD in natural products chemistry/food chemistry/biochemistry or a similar field Extensive competence in optimizing extraction and fermentation of natural metabolites, in particular primary metabolites including proteins/peptides, lipids, sugars Demonstrated competence and experience in fractionation/enrichment/purification of primary metabolites, particularly proteins and peptides (by dialysis, ultrafiltration, ion exchange, gel filtration and other methods) Demonstrated experience in qualitative/quantitative analysis, characterization and structure/sequence determination of (primary) natural metabolites (by NMR, LC-MS, GC-MS, SDS-PAGE, Edman degradation and other relevant methods) A full driving licence Evidence of scientific publication in high-ranking journals and dissemination of results at conferences Demonstrated experience in writing research proposals and conference papers Excellent verbal and written communication skills with proven ability to effectively analyse information and produce clear, concise reports or documents requiring interaction with other parties Ability to solve problems by using discretion, innovation and the exercise of high level of diagnostic skills within areas of functional responsibility or professional expertise Planning and organizational skills, with the ability to prioritise multiple tasks, set and meet deadlines Demonstrated laboratory management skills (managing stocks of consumables, laboratory organization etc) Proficiency with basic informatics tools (Excel, PowerPoint, basic informatics etc) Ability to work independently, motivation, enthusiasm and curiosity Desirable skills: Experience in proteomics and/or metabolomics applications Prior hands-on experience with in vitro biological assays, set up and testing Evidence of outreach activities and/or links to industry Experience of IP procedures relevant to university research Informal enquiries may be made to Prof. Deniz Tasdemir at deniz.tasdemir@nuigalway.ie Salary: €38,286 p.a. (public sector pay policy rules pertaining to new entrants will apply) Start date: 15th November 2012 To apply: Applications should be sent as a single file (in Word or PDF only) and include; 1) a covering letter stating the reason and suitability for applying for this specific research project, 2) a full curriculum vitae, and 3) the names and contact details of at least three but not more than five referees who can be contacted for confidential references to: deniz.tasdemir@nuigalway.ie Please put reference number NUIG-83-12 in subject line of e-mail when submitting application. Closing date extended to 5pm on Friday 19th October 2012 National University of Ireland, Galway is an equal opportunities employer