Gastrointestinal Tract Xvi: Gi Homeostasis, The Microbiome And The Barrier, Development And Disease August 2-7, 2015 Steamboat Springs, Colorado Organizers: Richard M Peek, Jr., MD Professor of Medicine and Cancer Biology Director, Division of Gastroenterology, Hepatology and Nutrition Vanderbilt University Medical Center 2215 Garland Avenue, 1030C MRB IV Nashville, TN 37232, USA Phone: 615-322-5200 Fax: 615-343-6229 Email: richard.peek@vanderbilt.edu Jason Mills, MD/PhD Associate Professor of Medicine Associate Director, Washington University Digestive Disease Center Washington University School of Medicine 660 S. Euclid Avenue, Campus Box 8124 St. Louis, MO 63110, USA Phone: 314-362-4213 Fax: 314-632-7487 Email: jmills@wustl.edu Melissa H. Wong, PhD Associate Professor Vice Chair of Cell and Developmental Biology Oregon Health & Science University 3181 SW Sam Jackson Park Rd, Mailcode L215 Portland, OR 97239, USA Phone: 503-494-8749 Fax: 503-494-4253 Email: wongme@ohsu.edu 9 February 2016 Sunday, August 2, 2015 Time 4:00 p.m. – 9:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 8:00 p.m. 8:00 p.m. – 9:00 p.m. Title/Topic Event Conference Registration Welcome Reception DINNER Keynote: "The human microbiome: at the interface of health and disease" Martin Blaser, MD New York University School of Medicine Title/Topic Event BREAKFAST Conference Registration 1) Title of Session: GI Stem Cells Session Chair: Susan Henning, University of North Carolina “Intestinal stem cell hierarchy” Calvin Kuo, Stanford University “Regulatory niche of the intestinal stem cell” Linheng Li, Stowers “Quiescent gastric stem cells in the Drosophila intestine” Craig Micchelli, Washington University School of Medicine Monday August 3, 2015 Time 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 10:30 a.m. 10:30 a.m. – 11:00 a.m. 11:00 a.m.-12:00 p.m. Morning Coffee Break and Group Photo ePoster session 12:00 p.m. – 1:00 p.m. 6 ePoster presentations selected from junior faculty and trainee abstracts LUNCH 1:00 p.m. – 3:00 p.m. Free time 3:00 p.m. – 4:00 p.m. Breakout session: Meet the experts 4:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 9:00 p.m. Poster Session I Conference Registration DINNER 2) Title of Session: The Microbiome and Health: Probiosis, Symbiosis, and Dysbiosis in the GI Ecosystem 9 February 2016 Moderator: Wayne Lencer, Dana Farber/Harvard Panel & Affiliation: Phil Daschner, NIH; Jill Carrington, NIH; Michael Grey, NIH; Kim Barrett, UC San Diego; Sean Colgan, University of Colorado Session Chair: Gail Hecht, Loyola University “Redox signaling and the gut microbiota” Andrew Neish, Emory University “Zebrafish as a model to study bacterial-host symbiosis” Karen Guillemin, University of Oregon “How microbiota-immune system interactions promote symbiosis” Lora Hooper, University of TexasSouthwestern “Defining, promoting, and maintaining a healthy microbiota” Justin Sonnenburg, Stanford University Short presentations selected from junior faculty and trainee abstracts Tuesday, August 4, 2015 Time 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 10:30 a.m. 10:30 a.m. – 11:00 a.m. 11:00 a.m. – 12:00 p.m. Title/Topic Event BREAKFAST Conference Registration 3) Title of Session: Mucosal Immunity Session Chair: Cormac Taylor, University College Dublin “Antigen presentation across the gut epithelium” Rodney Newberry, Washington University School of Medicine “Nod-like and Toll-like receptors in inflammatory bowel disease” Gabriel Nuñez, University of Michigan “Cytokines and metaplasia in the stomach” Richard Di Paolo, St. Louis University Morning Coffee Break ePoster session Moderator: Deborah Gumucio, University of Michigan 6 ePoster presentations selected from junior faculty and trainee abstracts 12:00 p.m. – 1:00 p.m. 1:00 p.m. – 4:00 p.m. 4:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 9:00 p.m. LUNCH Free time Poster Session II Conference Registration DINNER 4) Title of Session: Transport, tight junctions and barrier functions “Transport, barrier maintenance and pathogens” 9 February 2016 Session Chair: Asma Nusrat, Emory University Mark Donowitz, Johns Hopkins University “Cytokines, cytoskeleton, tight junctions and the barrier” Jerrold Turner, University of Chicago “Growth factors and epithelial barrier function” Mark Frey, University of Southern California Short presentations selected from junior faculty and trainee abstracts Wednesday, August 5, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 10:30 a.m. Title/Topic Event BREAKFAST Conference Registration 5) Title of Session: Host and microbial mediators of disease Session Chair: James Casanova, University of Virginia “Novel pathogenic functions for bacterial cell wall constituents” Nina Salama, University of Washington “The duality of EGFR in inflammation-associated cancer” Brent Polk, University of Southern California “Salmonella effector proteins and host cell responses” Beth McCormick, University of Massachusetts 10:30 a.m. – 11:00 a.m. 11:00 a.m. – 12:00 p.m. Morning Coffee Break Short presentations selected from junior faculty and trainee abstracts 12:00 p.m. – 1:00 p.m. 1:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 9:00 p.m. LUNCH Free time Conference Registration DINNER 6) Title of Session: Dedifferentiation and reprogramming in development and cancer 9 February 2016 Session Chair: Linda Samuelson, University of Michigan “Early events in intestinal neoplasia” Owen Sansom, Beatson Institute, Glasgow, Scotland “Stem cell plasticity in the stomach and other GI organs” Meri Huch, Gurdon Institute, University of Cambridge “Differentiation, dedifferentiation, transcription factors and Steven Leach, Sloan-Kettering pancreatic acinar cells” “Helicobacter, Wnt, Hippo, reprogramming and metaplasia” Masanori Hatakeyama, University of Tokyo Short presentations selected from junior faculty and trainee abstracts Thursday, August 6, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 7:30 a.m. – 12:00 p.m. 9:00 a.m. – 10:30 a.m. Title/Topic Event BREAKFAST Conference Registration 7) Epithelial injury, regeneration and disease Session Chair: Kay Lund, University of North Carolina “Notch signaling regulation in cancer” Noah Shroyer, Baylor College of Medicine “Bioengineering the intestine” Tracy Grikschiet, UCLA “Gastric disease and regeneration” Juanita Merchant, University of Michigan 10:30 a.m. – 11:00 a.m. 11:00 a.m. – 12:00 p.m. Morning Coffee Break Short presentations selected from junior faculty and trainee abstracts 12:00 p.m. – 1:00 p.m. 1:00 p.m. – 6:00 p.m. 6:00 p.m. – 7:00 p.m. 7:00 p.m. – 7:15 p.m. 7:15 p.m. – 9:00 p.m. LUNCH Free time DINNER Business meeting 8) Title of Session: Cutting edge techniques/concepts in GI research 9 February 2016 Session Chair: Manuel Amieva, Stanford University “iPS cells in translational medicine” James Wells, University of Cincinnati “Manipulating the intestine ex vivo with gut culture” Scott Magness, University of North Carolina “Exosomes and the GI tract” Robert Coffey, Vanderbilt University “4D-imaging of the intestine” Ken Lau, Vanderbilt University Friday, August 7, 2015 Time a.m. – Time p.m. 7:30 a.m. – 9:00 a.m. 9:00 a.m. Title/Topic Event BREAKFAST Boxed Snacks to Go And DEPARTURES END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 www.faseb.org/src 9 February 2016