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MINERVA PEDIATRICA
A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index
Expanded (SciSearch), Scopus
Impact Factor 0,433
Frequency: Bi-Monthly
ISSN 0026-4946
Online ISSN 1827-1715
Minerva Pediatrica 2010 October;62(5):431-6
ORIGINAL ARTICLES
Incidence of urinary tract infection in neonates with septicemia: a prospective study
Mohammad Milani Hosseini S. 1, Ataei N. 2, Khalafi F. 1, Sheikhvatan M. 3
Department of Neonatology, The Children’s Hospital Medical Center School of Medicine
Medical Sciences/University of Tehran;
2 Department of Pediatric Nephrology, The Children’s Hospital Medical Center, School of
1
Medicine, Medical Sciences/University of Tehran;
3 Medical Science/ University of Tehran, Tehran, Iran
AIM: The aim of this study was to investigate the incidence and clinical course of urinary
tract infection (UTI) in neonates with septicemia and also determine the most common UTI
manifestations in hospitalized neonates.
METHODS: A cross-sectional study was conducted on consecutive febrile infants aged 1 to
56 days that were hospitalized in the neonatal intensive care unit. In all neonates with
positive urine culture, scintigraphy with technetium-99m -labeled dimercaptosuccinic acid
(DMSA) and ultrasonography (US) were done. Voiding cystourethrography was performed
in the course of the illness, generally within 5-7 days of hospitalization.
RESULTS: Positive blood culture was detected only in 9% of patients. However, 5% of
them had positive urine culture. Positive Abnormal US findings were present in 2 of 5
(40%) and vesicoureteral reflux (VUR) was present in 1 of 5 (20%) of infants with positive
urine culture.
CONCLUSION: DMSA scan revealed renal parenchymal abnormalities in 3 of 5 (60%)
neonates with urosepsis. The incidence of UTI in neonates with septicemia is low. All
neonates with sepsis and positive urine culture should undergo a screening renal
scintigraphy and cystogram for identifying renal parenchymal involvement and urinary
tract abnormalities.
language: English
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