ML604: Biomedical Instrumentation Instructor: Supriya Babu Phone: 9886062127 Office: Dept. of Medical Electronics E-mail: Supriya.b@msrit.edu Outside the class Friday: 2:40 to 3:45 PM and Saturday 10 AM to 11 AM contact Hours Description: Recent advances in medical field have been fuelled by the instruments developed by the Bio-Medical and Instrumentation Engineers. Bedside patient monitoring systems, Medical diagnostic systems are few names which have been contributed by engineers. Now health care industry uses many instruments which are to be looked after by instrumentation engineers. This subject will enable the students to learn the basic principles of different instruments/equipment used in the health care industry. Proficiency in this area will widen the knowledge and skill of graduates in the field of biomedical instrumentation Goals: Understanding the requirements of various biomedical instruments. Understanding of various components of Biomedical Instruments and their functioning. Build various instruments using different blocks. Requirements: 85% overall attendance 40% CIE marks Completing all the lab experiments A mini project NO Plagiarism Resources: 1. Text Book (TB1): Handbook of Biomedical Instrumentation by R. S. Khandpur, 2nd Edition, Tata McGraw Hill, 2003 2. Text Book (TB2):Biomedical Instruments and Measurements by Leslie Cromwell, Fred J. Weibell and Erich A. Pfieffer, 2 nd Edition, PHI Publications 3. Reference Book (RB): Medical Instrumentation: Application And Design, 3Rd Ed, by John G Webster, Wiley India Publications, 2007 4. Lecture slides 5. Model questions Evaluation: 1. Three Tests of 25 marks each, Tests 1 and 2 compulsory, test 3 is improvement 2. 3 Marks for class attendance above 85% + 2 marks for asking questions in class) 3. Laboratory 20 Marks a. 10 marks for record – (attendance + asking questions + viva + write-up = 1 +1 +3 +5) b. 10 Marks for mini project (07→conduction + 03→report) Course Schedule: Week Topic Required Reading Jan 21 - 26 No classes due to FDP TB1: Chapter 1; RB: Chapters 1 & 2 Jan 28 – Feb 2 Review of BSM, Patient Monitoring Systems TB1: Chapters 1, 6; RB: Chapters 7 & 8 Jan 28 and 30: Labs: Introduction to BMI Lab and Design of experiments Feb 4 - 9 Patient Monitoring Systems, Foetal Monitoring Instruments TB1: Chapter 6 & 8; RB: Chapters 7 & 8 Feb. 5 & 6: Lab: Experimentation based on the design in previous lab, according to Mini-project group; Output Characteristics of recorder for Bio Signal using: X-Y Recorder/ X-t Recorder, Operations of DSO Feb 11-16 Blood gas analyzers, Unit I Summary TB1: Chapter 15; RB: Chapter 10 Feb 12 & 13: Lab: Determination of Pulse Rate using Photo- and Mechanical Transducer and Measurement of ECG and derivation of heart rate, pulse transit time Feb 18-23 Respiratory measurements, Pulmonary function analyzers TB1: Chapter 13, TB2: Chapter 8; RB: Chapter 9 Feb 19 & 20:Lab: Determination of Respiratory Rate using Temperature Transducer Feb 25 – Mar 2 Pulmonary function analyzers TB1: Chapter 13, TB2: Chapter 8; RB: Chapter 9 Feb 26 & 27:Lab: Demonstration of interfacing the following equipment: Spirometer and Ventilator Test 1: 28 Feb, Syllabus: Unit I and Unit II till Pulmonary function analyzers Mar 4 – Mar 9 Ventilators TB1: Chapter 33, TB2: Chapter 8; RB: Chapter 13 Mar 5& 6: Labs: Demonstration of interfacing the following equipment: Oximeter and Haemodialysis Machine Mar 11- Mar 16 Audiometers TB1: Chapter 17, TB2: Chapter 11 Mar 12 & 13: Labs: Determination of Hearing Loss by Air conduction & bone Conduction tests using Audiometer Mar 18 - 23 Hearing aids TB1: Chapter 17 Mar 19 & 20: Labs: Design of basic Hearing Aid Mar 25 - 30 Oximeters TB1: Chapter 10 Mar 26 & 27: Demonstration of interfacing the following equipment: Oximeter and Haemodialysis Machine Apr 1 -6 Oxygenators TB1: Chapter 10 Apr 2 & 3: Determination of percentage Transmittance, Absorbance & Concentration of given solutions using Spectrophotometer Page 2 Apr 4: Test 2: Syllabus: Unit II – Ventilators and Unit III Apr 8 - 13 Cardiac Pacemakers TB1: Chapter 25; RB: Chapter 13 Apr 9 & 10: Labs: Basic Design of a Cardiac Pacemaker Apr 15 - 20 Cardiac Defibrillators TB1: Chapter 26; RB: Chapter 13 Apr 16 & 17: Labs: Demonstration of Cardiac Defibrillator and of Physiotherapy Equipment and Electrotherapy Equipment Apr 22 - 27 Arrhythmia & Ambulatory Monitoring Instruments and Hemodialyser TB1: Chapter 7 & 30; RB: Chapter 13 Apr 24: Lab: Batch 2: Principle & Working of Ultrasound Scanner Apr 29 – May 4 Hemodialyser TB1: Chapter 30; RB: Chapter 13 Apr 30: Lab: Batch 1: Principle & Working of Ultrasound Scanner May 4: Mini-project Demo and Report Submission May 6 –11 Lithotripsy May 7 & 8: Labs: Repetition of any experiment + final Viva May 6: Test 2: Syllabus: Unit IV & Unit V - Hemodialyser Daily Schedule of Classes JANUARY MON TUE WED THU FRI SAT SUN 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 No Class: FDP No Class: FDP No Class: FDP No Class: FDP 28 29 Introduction and instructions Patient Monitoring Systems: System concepts 30 31 Cardiac monitor Page 3 MON TUE WED THU FRI 1 SAT SUN 2 3 9 10 16 17 23 24 FEBRUARY Bedside patient monitoring systems 4 5 Central monitors Foetal Monitoring Instruments: Cardiotochograph 11 12 Measurement of Blood PH Measurement of Blood PO2 & PCO2 18 19 Respiratory measurements: Instrumentation & mechanism for breathing Respiratory therapy equipments 25 26 Pneumotachometers Pulmonary function analysers MARCH MON 6 13 20 27 TUE 4 5 Need for ventilators, Types – manual & automatic Oxygen therapy 11 12 Audiometry, types & causes of hearing losses Basic audiometer & audiograms 18 19 Hearing aids: Basic scheme, Electro acoustic properties Types of hearing aids 25 26 pulse oximeter skin reflectance oximeters 7 8 Monitoring Foetal heart rate Monitoring labour activity 14 15 A complete Blood Gas analyzer Summary 21 22 Pulmonary function measurement Spirometry 28 Test 1 WED 6 13 20 27 THU FRI SAT SUN 1 2 Test 1 Test 1 7 8 9 10 Special equipments – Control & conditioning devices IPPB ventilator 14 15 16 17 Pure tone audiometer & speech audiometer tests Evoked response audiometry system 21 22 23 24 Cochlear implants Oximetry, Ear oximeter 28 29 30 31 intravascular oximeter and Summary Good Friday Holiday Page 4 3 & Summary APRIL MON TUE 1 2 Bubble oxygenator thin film oxygenator 8 9 membrane oxygenator Need for pacemakers & external & implantable pacemakers 15 16 Cardiac Defibrillators: Based on the location Cardiac Defibrillators: Based on the mode of operation 22 23 Cardiac Arrhythmias & ambulatory monitoring instruments Mahaveer Jayanthi: Holiday 29 30 Dialyser machines – Coil type Parallel plate type & Hollow fibre type MAY MON WED 3 10 17 24 TUE THU FRI SAT SUN 4 5 6 Test 2 Test 2 Test 2 11 12 13 14 UGADI: Holiday pacing system analyzer 18 19 20 21 Defibrillator electrode Cardioverters & Summary 25 26 27 28 Arrhythmia monitor Dialysis, Ideal kidney characteristics, Dialysis membrane WED THU FRI 1 2 3 Holiday Electronic control & monitoring – blood leak detector Hemodialyser: temperature & conductivity measurement SAT 7 SUN 4 5 11 12 6 7 8 9 10 Test 3 Test 3 Test 3 Percutaneous removal of kidney stones extracorporeal type Lithotripsy 13 14 15 16 17 18 19 Basava Jayanthi: Holiday Summary 20 21 22 23 24 25 26 27 28 29 30 31 Page 5