Galith Abourbeh E-mail: abourbehg@hadassah.org.il CURRICULUM VITAE Born in Israel – 1973 EDUCATION and Employment 2010 - Hadassah Hebrew University Hospital, Radiochemistry/ Cyclotron/ microPET Unit, Jerusalem, Israel. Researcher; Pre-clinical project manager in the field of PET molecular imaging. 2008-2009 Atomic Energy Commission (CEA), Department of Life Sciences (DSV), Laboratory of Experimental Molecular Imaging (LIME), Orsay, France. Post doctoral research under the supervision of Prof. Bertrand Tavitian. Research project: development of rodent models of experimental autoimmune encephalomyelitis (EAE) for studying neuroinflammation in multiple sclerosis using positron emission tomography (PET). 2007 Hadassah Hebrew University Hospital, Radiochemistry/ Cyclotron Unit, Jerusalem, Israel. Researcher; project management in the field of molecular imaging in PET-Oncology 2002-2006 Hadassah Hebrew University Hospital, Radiochemistry/ Cyclotron/Unit, Jerusalem, Israel. The Hebrew University of Jerusalem, The Alexander Silberman Institute of Life Sciences, Department of Biological Chemistry, Unit of Cellular Signaling, Jerusalem, Israel. Direct course to Ph.D. in molecular imaging and biochemistry under the supervision of Prof. Eyal Mishani and Prof. Alexander Levitzki. Title of Ph.D. thesis: “Exploring Radiolabeled Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) as Imaging Agents for Positron Emission Tomography (PET)”. 2000-2001 The Hebrew University of Jerusalem, Faculty of Medicine, School of Pharmacy, Jerusalem, Israel. M.Sc Pharm. degree as part of the direct course to Ph.D. Magna cum laude 1994-1998 The Hebrew University of Jerusalem, Faculty of Medicine, School of Pharmacy, Jerusalem, Israel. B. Pharm. Bachelor degree in Pharmacy. Summa cum laude. PUBLICATIONS add titles of papers 1. Mishani E., Abourbeh G., Rozen Y., Jacobson O., Laki D., Ben-David I., Levitzki A. and Shaul M. 2004, Nucl Med Biol (31), 469-76. 2. Shaul M., Abourbeh G., Jacobson O., Rozen Y., Laki D., Levitzki A. and Mishani E. 2004, Bioorg Med Chem (12), 3421-9. 1 Galith Abourbeh E-mail: abourbehg@hadassah.org.il 3. Mishani E., Abourbeh G., Jacobson O., Dissoki S., Ben Daniel R., Rozen Y., Shaul M. and Levitzki A. 2005, J Med Chem (48), 5337-5348. 4. Abourbeh G., Dissoki S., Jacobson O., Litchi A., Ben Daniel R., Laki D., Levitzki A. and Mishani E. 2007, Nucl Med Biol (34), 55-70. 5. Mishani E. and Abourbeh G. 2007, Curr Top Med Chem (7), 1755-72 (Review) 6. Dissoki S., Aviv Y., Laky D., Abourbeh G., Levizki A. and Mishani E. 2007, Appl Radiat Isot (65), 1140-51. 7. Mishani E., Abourbeh G., Eiblmaier M. and Anderson C. 2008 Curr Pharm Des (14), 2983-98. 8. Abourbeh G., Thézé B., Maroy R., Dubois A., Dollé F., Fontyn Y., Brulon V., Tavitian B. and Boisgard R. 2012 J Neurosci (32):5728-36. 9. Abourbeh G., Shir A., Mishani E., Ogris M., Rödl W., Wagner E. and Levitzki A. 2012 IUBMB Life (64):324-30. 10. Ilovich O., Abourbeh G., Bocher M., Freedman N., Billauer H., Dotan S., Danenberg H.D. and Mishani E. 2012 Mol Imaging Biol (14):625-636. 11. Kesner A.L., Abourbeh G., Mishani E., Chisin R., Tshori S. and Freedman N. 2013 EJNMMI Res. (3):29 ??? 12. Jacobson O., Abourbeh G., Tsvirkun D. and Mishani E. 2013 Nucl Med Biol In Press. PRESENTATIONS IN SCIENTIFIC MEETINGS 1. Mishani E., Levitzki A., Abourbeh G., Ortu G., Ben-David I., Rozen Y., Lester H., Fridman N., Chisin R. Novel irreversible [ 11C]EGFR-TK inhibitors for cancer imaging diagnosis. The 50th Annual Conference of the Society of Nuclear Medicine (2003), New Orleans, USA. Lecture 2. Abourbeh G., Boisgard R., Dollé F., Maroy R., Dubois A., Brulon V., Fontyn Y., Tavitian B. PET imaging of spinal cord lesions in rat experimental autoimmune encephalomyelitis using the peripheral benzodiazepine receptor ligand, [ 18F]DPA714. The fourth European Molecular Imaging Meeting (2009), Barcelona, Spain. Lecture PATENTS 1. E. Mishani, Y. Rozen, G. Abourbeh and A. Levitzki. Novel EGFR-TK irreversible inhibitors for cancer therapy, radiotherapy and diagnosis. U.S. Patent No. 7,172,749 (2007). 2. S. Dissoki, G. Abourbeh, A. Levitzki, E. Mishani. Labeled EGFR Irreversible biomarkers: Anilinoquinazoline-7-[F-18]-PEG derivatives. Applied to U.S. patent (2006). 3. E. Mishani, H. Billauer, G. Abourbeh, S. Dotan, N.M.T. Freedman, H. Danenberg, M. Bocher. Ammonium salts for myocardial perfusion imaging. Applied to U.S. patent (2011). Grants 2011-2014 Israel Science Foundation (ISF), Carbon-11/ Fluorine-18 labeled ammonium salts as myocardial perfusion PET imaging agents. Eyal Mishani (PI), Galith Abourbeh, Haim Danenberg, Moshe Bocher. 2