Chapter 2 Vocabulary List adenine allosteric amino acid bicarbonate ion bioinformatics buffer carbohydrate catabolism chaperone protein/chaperonin coenzyme cofactor competitive inhibition confirmation covalent bond cytosine denatured -a nucleotide that binds to thymine and uracil. It is a purine -a type of enzyme that changes its conformation and its function in response to a modifier -organic molecule composed of an amino group and an acid group; covalently bonds to produce peptide molecules -ion that participates in buffering the blood, and the form in which carbon dioxide is transported in the bloodstream -computer technologies used to study the genome -substance or group of substances that tend to resist pH changes of a solution, thus stabilizing its relative acidity and basicity -class of organic compounds that includes monosaccharides, disaccharides, and polysaccharides -metabolic process that breaks down large molecules into smaller ones; catabolic metabolism -molecule that interacts with a protein so that it folds into its proper shape -nonprotein organic molecule that aids the action of the enzyme to which it is loosely bound -nonprotein adjunct required by an enzyme in order to function; many cofactors are metal ions, others are coenzymes -form of enzyme inhibition where the substrate and inhibitor are both able to bind to the enzyme’s active site. Only when the substrate is at the active site will product form -shape -chemical bond in which atoms share one pair of electrons -one of four nitrogen-containing bases in the nucleotides composing the structure of DNA and RNA; pairs with guanine -loss of an enzyme’s normal shape so that it DNA(deoxyribonucleic acid) disaccharide electron endergonic reaction energy of activation exergonic fatty acid fibrous protein functional groups globular protein glucose glycerol guanine hydrolysis reaction hydrogen bond no longer functions; caused by a less than optimal pH and temperature -nucleic acid polymer produced from covalent bonding of nucleotide monomers that contain the sugar deoxyribose; the genetic material of nearly all organisms -sugar that contains two units of monosaccharide -negative subatomic particle, moving about in an energy level around the nucleus of an atom -chemical reaction that requires an input of energy; opposite of exergonic reaction -energy that must be added in order for molecules to react with one another -chemical reaction that releases energy; opposite of an endergonic reaction -molecule that contains a hydrocarbon chain and ends with an acid group -a protein that has only a secondary structure; generally insoluble; includes collagens, elastins, and keratins -specific cluster of atoms attached to the carbon skeleton of organic molecules that enters into reactions and behaves in a predictable way -most of the proteins in the body; soluble in water or salt solution; includes albumins, globulins, histones -six-carbon sugar that organisms degrade as a source of energy during cellular respiration -three-carbon carbohydrate with three hydroxyl groups attached; a component of fats and oils -one of four nitrogen-containing bases in nucleotides composing the structure of DNA and RNA; pairs with cytosine -splitting of a bond by the addition of water, with the H+ going to one molecule and the OH- going to the other -weak bond that arises between a slightly positive hydrogen atom of one molecule and a slightly negative atom of another molecule or between parts of the same molecule induced fit model ionic bond isomers isotope lipid metabolism molecule monosaccharide neutrons noncompetitive inhibition nucleic acid nucleotide peptide bond phospholipid polar covalent bond polymer -change in the shape of an enzyme’s active site that enhances the fit between the active site and its substrate(s) -chemical bond in which ions are attracted to one another by opposite charges -molecules with the same molecular formula but a different structure, and therefore a different shape -atom of the same element having the same atomic number but a different mass number due to the number of neutrons -class of organic compounds that tends to be soluble in nonpolar solvents; includes fats and oils -all of the chemical reactions that occur in a cell during growth and repair -union of two or more atoms of the same element; also, the smallest part of a compound that retains the properties of the compound -simple sugar; a carbohydrate that cannot be decomposed by hydrolysis -neutral subatomic particles, located in the nucleus and assigned one atomic mass unit -form of enzyme inhibition where the inhibitor binds to an enzyme at a location other than the active site; while at this site, the enzyme shape changes, the inhibitor is unable to bind to its substrate, and no product forms. -polymer of nucleotides; both DNA and RNA are nucleic acids -monomer of DNA and RNA consisting of a 5carbon sugar bonded to a nitrogenous base and a phosphate group -type of covalent bond that joins two amino acids -molecule that forms the bilayer of the cell’s membranes; has a polar, hydrophilic head bonded to two nonpolar, hydrophobic tails -bond in which the sharing of electrons between atoms is unequal -macromolecule consisting of covalently bonded monomers; for example, a polypeptide polysaccharide prion protein proton RNA(ribonucleic acid) ribose steroid surface tension thymine tracer uracil polypeptide is a polymer of monomers called amino acids -polymer of many amino acids linked by peptide bonds -polymer made from sugar monomers; the polysaccharides starch and glycogen are polymers of glucose monomers -infectious particle consisting of protein only and no nucleic acid -molecule consisting of one or more polypeptides -positive subatomic particle located in the nucleus and assigned one atomic mass unit -nucleic acid produced from covalent bonding of nucleotide monomers that contain the sugar ribose; occurs in three forms: messenger RNA, ribosomal RNA, and transfer RNA -pentose sugar found in RNA -type of lipid molecule having a complex of four carbon rings -force that holds moist membranes together due to the attraction of water molecules -one of four nitrogen containing bases in nucleotides composing the structure of DNA; pairs with adenine -substance having an attached radioactive isotope that allows a researcher to track its whereabouts in a biological system -pyrimidine base that occurs in RNA, replacing thymine