Jeju National University
19-01-2012
Dear Editors,
Please find here enclosed a manuscript entitled “Immunomodulatory Acticivity of
Panchgavya” by Paliwal et al., which we are submitting for publication in International
Journal of Advances in Pharmaceutical Research (IJAPR). This manuscript has not been
submitted to another journal and will not be published elsewhere within one year after its
publication in this journal, and all authors have read the paper and none of the authors have a
financial conflict of interest. Experiment using animals were done with the permission of
institutional animal ethical committee of College of Veterinary Science and Animal
Husbandry, MPPCVV, Jabalpur (M.P.).
We demonstrated the immunomodulatory activity of Panchgavya (PG) against
cyclophosphamide induced immunosuppression. Panchgavya is combination of five major
substances obtained from cow that includes cow dung, urine, milk, curd and ghee.In this
study, the animals treated with Panchgavya showed increased neutrophil adhesion test
(percent), absolute lymphocyte count (per cumm of blood) and serum gamma globulin conc.
(g/dl). These finding indicates immunomodulatory activity of Panchgavya on
cyclophosphamide induced immunosuppression as evidenced by cell mediated and humoral
immune responses. Thus, we believe that Panchgavya (PG) may have considerable potential
as immunomodulator against various immune disorders.
We hope that this manuscript is acceptable for publication in your peer reviewed journal.
Dr. Swatantra Kumar Singh (BVSc&A.H., MVSc (JRF), DIM, NET, PhD scholar)
PhD Researcher
Department of Medicine and Radiobiological Research
College of Veterinary Medicine and Veterinary Medical Research Institute
Jeju National University
Jeju City, Ara-dong 1
South Korea
email:drswatantravet@gmail.com, dr.swatantravet@rediffmail.com
Mob: +82-10-5525-1947
Phone: (Lab) 82-64-754-3374, (R) 82-64-729-7206
Fax: 82-64-756-3354