Research Division of the Department of Pediatrics The Medical City Year End Report for 2013 TEAM Head: Dr. Jacqueline Navarro Resident Coordinator: Dr. Kristine Anne Victorino Residents' Research Unit Head: Dr. Jacqueline Navarro Members: Dr. Cristina Bernardo Dr. Michelle De Vera Dr. Josephine Dela Pena Dr. Miranila Hernandez-Matibag Dr. Ronnel Matibag Consultants' Research Unit Head: Dr. Eva Cutiongco-Dela Paz Members: Dr. Carina Cruz-Quimbo Dr.Erlinda Cuisia-Cruz Dr. Emelita Leh Dr. Susanna Lim Lopez Dr. Olympia Malanyaon Research Publication, Networking, and Presentation Unit Members: Dr. Cynthia Aguirre Dr. Charito Corpuz Dr. Eileen Alikpala-Cuajunco Dr. Jocelyn Resurreccion Dr. Teresita Rabanal Dr. Emily Resurreccion ACTIVITIES FOR YEAR 2013 I. February 2013: Research Division Meeting Activity: Research Team, Authors and Co-Authors Meeting Date and Time: Feb 1, 2013 Friday, 3-5 PM Venue: Conference Room 4th Floor Program: 3:00-3:15 PM Review of Resident Research Accomplishments 3:15-3:30 PM Targets for 2013 3:30-4:00 PM How to publish papers: Dr. Eva Cutiongco-De La Paz 4:00-4:30 PM Discussion: Commitments and Timelines II. March 2013: Residents’ Research Committee meeting Agenda: Activities for year 2013, Case Report Contest and Residents’ Research Contest Date and Time: March 2013, 7pm Venue: Chelsea, Podium Attendees: Dr.Jacqueline Navarro Dr. Michelle de Vera Dr. Josephine dela Pena Dr. Cristina Bernardo Dr. Miranila Hernandez-Matibag Dr. Ronnel Matibag Dr.Kristine Anne Victorino III. June 2013: Residents Research Unit Meeting Agenda: Residents’ Research Paper, Case Report Contest, Research Contest, Publication updates/Plans Date and Time: June 24,2013, 7:30-9:30pm Venue: Kimono Ken Restaurant, Rockwell Ortoigas Attendees: Jacqueline Navarro Michelle de Vera Miranila Hernandez-Matibag Ronnel Matibag IV. July 2013: Residents’ Case Report Contest Date and Time: July 26, 2013, 12nn-4pm Venue: Conference Rooms 1&2, Podium Building, The Medical City Cases & Participants: 1. CAN YOU STOMACH IT?: Hypovolemic Shock secondary to Upper GI Bleed secondary to Duodenal Bulb Ulcer with Arterial Bleed Presented by Dr. Ma. Victoria dela Paz 2. Forearmed is Forwarned: A Case of Reversible Ischemic Neurologic Deficit in a 17-year old Pediatric Patient Presented by Dr. Anna Samantha Imperial 3. The Potential of Mesenchymal Stem Cells in Spinal Muscular Atrophy Type 1 Presented by Dr. Rianna Leigh R. Salazar 4. Pulmonary Valve Atresia with Single Ventricle Presented by Dr. Ma.Cecilia Del Carmen 5. The Giant Slayer: A Rare Case of a Giant Intracranial Aneurysm in a 10 year old Female Presented by Dr. Kathlene Marie A. Barcelona, Dr. Sheila Quitaleg 6. First Transcatheter Stent Implantation for Coarctation of the Aorta in a Filipino Pediatric Patient Presented by Dr. Marco Romulo Manzano 7. Total Colonic Aganglionosis in a Preterm Infant: A Case Report Presented by Dr. Cathleen Recana-Lu Winners: 1st Place- First Transcatheter Stent Implantation for Coarctation of the Aorta in a Filipino Pediatric Patient- Dr. Marco Romulo Manzano 2nd Place- The Giant Slayer: A Rare Case of a Giant Intracranial Aneurysm in a 10 year old Female - Dr. Kathlene Marie A. Barcelona, Dr. Sheila Quitaleg Total Colonic 3rd Place- Aganglionosis in a Preterm Infant: A Case Report- Dr. Cathleen Recana-Lu Prizes: 1st Place- P5,000 2nd Place- P3,000 3rd Place- 2,000 Judges Honorarium: P3,000 each Board of Judges: Dr. Berroya Dr. Luz del Rosario Dr. Lim-Lopez V. September 2013: Research Coordinators Meeting with Dr.Troy Gepte Date & Time: September 5,2013, 2-4pm Venue: Center for Healthcare Innovation Conference Room Attendees: Consultants and Resident research coordinators of each department VI. October 2013: Residents’ Scientific Research Contest Date and Time: October 4, 2013, 12nn-4pm Venue: Conference Rooms 1&2, Podium Building, The Medical City Research Papers & Participants: Poster Presentation Finalists 1. The Prevalence and Relationship of Constipation among Children Age 1-12 months and Formula Milk Feeding in a Tertiary Hospital - Charissa Karmel Balandra,MD 2. Outpatient Fluid Management of Dengue Fever - Cathleen Faye Recana-Lu,MD 3. A Retrospective Study on the relationship between the trend of WBC and Platelet Count with the morbidity of Dengue Fever - Ma. Cecilia Corazon Del Carmen,MD 4. Assessment of Renal Function in Children previously diagnosed with Acute Glomerulonephritis on 2006-2011 - Jocelyn Basbas-Lopez,MD 5. Liquid vs. Frozen form of Oral Rehydrating Solution in treating children with Acute Gastroenteritis, some signs of dehydration: A randomized trial - Liz Tamondong,MD 6. White Blood Cell Count in Determining Recovery in Pediatric Patients with Dengue Fever -Julie Clarissa Pangilinan,MD Oral Presentation Finalists 1.Topical Retapamulin Ointment, 1% (Altargo) plus Topical Retinoid 0.025% Cream, versus Topical Erythromycin 4% Gel plus Topical Retinoid 0.025% Cream for Mild to Moderate Acne among Adolescents in Purok Ilugin: A Randomized, Observer-Blinded, Noninferiority Study - Katrina Isabelle Arguelles-Rey,MD 2. Evaluation of the Use of the Tablet PC in a Philippine High School - Khlaire Pioquinto,MD 3. A Comparative Study on the Efficacy of Insect Repellants against Aedes Aegypti - Marco Romulo Manzano,MD 4. Prevalence of Microcytosis in G6PD Deficiency Patients and the Concurrence of Thalassemia and G6PD Deficiency - Soraya Sarapuddin,MD 5. Nebulization using Normal Saline Solution or Bronchodilators as adjunct treatment in children hospitalized with Community Acquired Pneumonia: A Retrospective Study - Marie Grace Delizo,MD 6. Clinical and Laboratory Profile of Patients diagnosed of Dengue Shock Syndrome with Dengue Myocarditis admitted at The Medical City - Sheila Quitaleg,MD 7. A Randomized Study on the Use of Retapamulin Ointment Compared with Mupirocin Ointment on the Treatment of Impetigo in Children -Frances Kaori Togezaki,MD Board of Judges: Ma. Cecilia D. Alinea, MD Maria Luz U. Del Rosario, MD Erasmo Gonzalo Llanes, MD Winners 1st Place: Clinical and Laboratory Profile of Patients diagnosed of Dengue Shock Syndrome with Dengue Myocarditis admitted at The Medical City - Presented by Sheila Quitaleg,MD 2ND PlaceTopical Retapamulin Ointment, 1% (Altargo) plus Topical Retinoid 0.025% Cream, versus Topical Erythromycin 4% Gel plus Topical Retinoid 0.025% Cream for Mild to Moderate Acne among Adolescents in Purok Ilugin: A Randomized, Observer-Blinded, Noninferiority Study - Presented by Katrina Isabelle Arguelles-Rey,MD A Comparative Study on the Efficacy of Insect Repellants against Aedes Aegypti -Presented by Marco Romulo Manzano,MD 3rd Place Evaluation of the Use of the Tablet PC in a Philippine High School - Presented by Khlaire Pioquinto,MD Best in Poster: The Prevalence and Relationship of Constipation among Children Age 1-12 months and Formula Milk Feeding in a Tertiary Hospital - Presented by Charissa Karmel Balandra,MD Prizes 1st Place: P8,000 2nd Place: P6,000 x 2 (winners) 3rd Place: P4,000 Judges Honorarium: P3,000 each x 3 = P9,000 Accomplishments/Publications I. Dr. Celeste Gomez presented her research paper in the American Academy of Asthma, Allergy, and Immunology Poster Presentation on February 22-26, 2013 at San Antonio, Texas U.S.A. II. Dr. Kristine Anne Victorino presented her Research paper in the PPS Annual Residents Oral Research Presentation on April 17,2013 at the PICC; She was awarded as second place. III. The Research Paper of Dr. Cathleen Recana was included in the Poster Presentation at the International Conference on Birth Defects on November 2013 at Cebu City. IV. 29th Annual Research Forum at The Medical City The following residents are finalists in the research contest which will be held on December 12, 2013 at The Medical City: 1. Analytical Category: Marco Romulo Manzano 2. Descriptive Category: Sheila Quitaleg, Khlaire Pioquinto 3. Case Report Category: Kathleen Barcelona/Sheila Quitaleg For Poster Presentation: 1. 2. 3. 4. Marco Manzano Khlaire Pioquinto Shiela QUitaleg/Kathleen Barcelona Grace Delizo V. FIRST Residents’ Research Contest Dr. Marco Manzano won first place in this contest, which was held on November 12, 2013 at Our Lady of Lourdes Hospital. Updates Third Year Research Papers The research papers of 9 third year residents and chief resident Dr.Jaymie Tang will be submitted to PPS on December 15,2013. Research Papers will also be submitted for PPS Convention-Poster Presentation in the year 2014. First Year Residents The first year residents have attended Task 1 to Task 6 in preparation for their research. The following are the assigned team leaders for first year residents: Resident 1. Kathlene Barcelona 2. Angelo Catacutan 3. Francesca dela Cruz 4. Victoria dela Paz 5. Ferrie Diza 6. Faida Durante 7. Izaskun Ganao 8. Anna Samantha Imperial 9. Grizell Ledres 10. Jordan Panganiban 11. Christine Pasana 12. Rianna Leigh Salazar 13. Grace Uy Team Leader Dr.Bernardo Dr. Bernardo Dr. dela Pena Dr.dela Pena Dr. de Vera Dr. de Vera Dr. Miranila Matibag Dr. Miranila Matibag Dr. Ronnel Matibag Dr. Ronnel Matibag Dr. Navarro Dr.Navarro Dr.Navarro Deadline of Submission for Final Protocol is on December 16, 2013. Journal Club There was a total of 9 journal club sessions for the year 2013, which was held every fourth Wednesday of the month at the Pediatrics office. All first year and third year residents have presented their journal appraisal from February to November 2013. ACTIVITIES IN 2014 Mission: Promotion, publication and utilization of quality, relevant and ethical research that benefits The Medical City’s pediatric patients, professional staff and communities it serves engaging the department’s strategic partners who share the department’s vision and passion. Objectives: 1. To facilitate the formulation of the research agenda and priority setting for the department 2. To motivate consultants and residents to do research 3. To provide trainings on research and build the capacity of the department for research 4. To guide consultants and residents in the conduct of the research 5. To advocate for research publication and utilization 6. To generate funding for research 7. To establish, manage and sustain relationship with research grantors Strategies: 1. Coordinate with the hospital’s research committee regarding research training. 2. Provide within the department training to include basic research methods, evidence based medicine and ethics in research 3. Provide opportunities for consultants and residents to engage in research related training and activities. 4. Identify potential sources of funding both locally and internationally and outline processes and requirements for a funding/grant application 5. Identify venues/ journals for publishing research papers and obtaining requirements for these 6. Identify venue for presentations (e.g. subspecialty format) of research papers both locally and internationally Policies: 1. The first year resident should have a research protocol co-authored by a pediatric board certified consultant of the TMC. The research topics should be approved by the Residents’ Research Unit and in compliance with the research agenda of the department and the hospital and the priority needs of the country and the Philippine Pediatric Society. 2. The second year resident should conduct, analyze data of his/her research and present in an appropriate format 3. The third year resident will revise and fine tune written manuscripts for submission to PPS and international and regional journals. 4. All researches shall be guided by the policies of the Hospital’s Research Committee as stated in The Medical City Operations and Procedures Manual No. 17. Likewise they have to comply with the TMC Pediatric Department Research Policies 5. All researches would be reviewed and approved by the department’s technical review board (TRB), hospital’s institutional review board (IRB) and the ethics review board (ERB). 6. Each resident will have consultant co-author/s, one of whom is a member of the research division. 7. The second year resident must complete the conduction, analysis and presentation of research before the end of the second year as a prerequisite for promotion to the 3rd year of residency. The 2nd yesr resident should have been issued a certificate of participation in the annual research presentation/ contest Procedures: 1. The residents will receive training through the Residents’ Research Unit (See Research Curriculum in Appendix A) and the Hospital’s Research Committee on the following topics: a. Research methodology b. Sample size and statistical analysis c. Writing scientific paper d. Evidence-based medicine e. Meta-analysis f. Economic Analysis g. Ethics in Research 2. The research protocol will be drafted in the first year level of training (from May to December) through the help of the research advisers provided by the Residents’ Research Unit and their co-authors. This will be done through a four-part research workshop tackling the different components of the research protocol. 3. Once protocols are made, they are submitted to the department of pediatrics’ technical review board (TRB) and the Hospital’s Institutional and Ethics Review Board (ERB). 4. The resident with their respective co-authors will present the research protocol to the Hospital’s Institutional and Ethical Review Board if required. 5. If funding would be requested, a grant application would be submitted to the hospital’s research committee 6. The conduct of research would be done from January to July of the second year level. The data analysis and paper writing would be done on August and September and presented in appropriate fora on October onwards. 7. The revised written paper would be submitted to the Research Division for review by the Research Publications Unit. The author together with the Research Publications Unit would assist the researcher in finding the appropriate venue/journal for its publication or the appropriate subspecialty forum where it could be presented. 8. The co-authors are to sign the completed written research paper before submission to PPS as part of the pediatric diplomate exam requirement. Evaluation Research is evaluated through several ways: 1. Through the department’s TRB, hospital’s IRB and ERB using the research proposal checklist (Table 1) and the evaluation used for judging papers (Table 2 and Table 3). 2. If for publication then the research is submitted to appropriate journals as guided by journal requirements for authors. Prepared by: Kristine Anne Victorino, MD