DRAFT
December 8, 2014
Terry Fox Ontario Node Symposium
Discovery, Detect, Treat: The translational horizon towards effective cancer therapy
Morning: Tumour Models
9:00-9:05
Rob Rottapel (TFRI Ontario Node), Opening Comments
9:05-10:05
Nahum Sonenberg (Goodman Cancer Centre, McGill, Montreal), Keynote Speaker
“The role of mRNA5ˈ cap-binding protein, eIF4E, in tumourigenesis and metastasis"
10:05-10:35
Sean Egan (Hospital for Sick Children, Toronto)
"Using mice to model metastatic breast cancer in humans"
10:35-11:05
Lois Mulligan (Queen's University, Toronto)
“RET revisited: Molecular mechanisms linking oncogenesid and neurogenesis”
11:05-11:20
Break
11:20-11:50
Sheila Singh (McMaster University, Hamilton)
“Molecular regulation and therapeutic targeting of Glioblastoma BTICs”
11:50am-12:20pm
Ming Tsao (Princess Margaret Cancer Center, Toronto)
“Targeting tumour stroma in non-small cell lung cancer”
12:30-1:30pm Lunch
Afternoon: Detection and Therapeutics
1:30-2:00pm Bradley Wouters Princess Margaret, Toronto)
“Epigenetic regulation of DICER and miRNA biogenesis during hypoxia promotes stem cell
phenotypes in breast cancer”
2:00-2:30pm Gregory Czarnota (Sunnybrook Hospital, Toronto)
“Ultrasound and MRI for cancer therapy”
2:30-3:00pm Rebecca Auer (Ottawa Hospital Research Institute, Ottawa)
“Postoperative anti-tumour T-cell dysfunction – Implications for combining surgery with
immunotherapy”
3:00-3:15pm
Break
3:00-3:30pm John Bell (Ottawa Hospital Research Institute, Ottawa)
“Oncolytoc Viruses: Replicating cancer therapeutics”
3:30-3:45pm Amélie Fradet-Turcotte (Durocher Lab, Lunenfeld, Toronto) (tentative)
“Ubiquitylation of histone H2A on lysine 13 and 15; a cornerstone in DNA double-strand
break signalling”
3:45-4:00pm Jarrett Adams (Sidhu Lab, CCBR, Toronto) (tentative)
“Using synthetic antibodies to target and modulate EPH receptors in cancer”
4:00-5:00pm Yossi Schlessinger (Yale University, USA), Keynote Speaker
“Cell signalling by receptor tyrosine kinases: From basic principles to cancer therapy”