BINDER BULLETIN AND UNIT STUDY OUTLINE UNIT 4: DNA and Genetics The Big Picture… Understanding that many of a person’s characteristics are determined by an interaction between genes (DNA) and the environment is key to understanding how we inherit our traits. Scientists have mapped out and determined the location of most of our genes, including those that are responsible for genetic disorders. Why might family members resemble one another? Prerequisite Knowledge…You should be able to: 1. Students should know that DNA is the molecule of heredity. 2. Students should be able to recognize that humans and other organisms resemble their parents. 3. DNA is the genetic material 4. The genetic material is organized into chromosomes 5. Sexual reproduction is responsible for producing genetically different offspring due to the special process that produces sperm and egg Suggested Resources: Homework and Classwork Assignments Laboratory Activities and Quizzes Textbook pages: pp. 95-102, 110-137 and 144-162 Websites: http://comelearnmore.com/websites-by-topic/genetics-games/ http://www.sciencespot.net/Pages/kdzbiogen.html http://pbskids.org/dragonflytv/games/game_dogbreeding.html Key Terms: DNA and Cell Division Cell cycle Interphase Replication Mitosis Chromosome Heredity Trait Genetics Fertilization Purebred Gene Alleles Dominant allele Cytokinesis Messenger RNA Transfer RNA Mutation Multiple allele Sex chromosomes Sex-linked gene Carrier Meiosis Incomplete dominance Codominance Recessive allele Hybrid Selective Breeding Clone Genetic engineering Genome Gene therapy DNA fingerprinting By the conclusion of this unit, students will know: _____1. DNA is stored as structures called chromosomes. _____2. Chromosome number is unique to each species. _____3. Each chromosome contains many genes along its length. _____4. Genes are hereditary units that control the expression of characteristics. _____5. Human characteristics can be in three categories; structural (anatomical), physiological, and behavioral. _____6. When organisms reproduce, they pass on this hereditary material to their offspring. _____7. Reproduction can be sexual or asexual. _____8. Sexual reproduction requires the production of separate sex cells. _____9. Sperm and egg are produced through a special type of cell division and have half the normal number of chromosomes of the organism. (23 total chromosomes, one of each pair from the original 46) _____10. Egg and sperm come together during fertilization. _____11. Sexual reproduction produces offspring that are genetically different from either parent but have some of the characteristics of both parents’ lineages. _____12. Organisms that are sexually reproducing are from the Animal, Plant, some members of the Fungal and some Protist Kingdoms. _____13. Asexual reproduction does not require the production and fusion of sperm and egg. _____14. Asexual reproduction requires only one parent and results in offspring that are genetically identical to that parent. _____15. Heredity is the passage of characteristics from parent to offspring. _____16. Another word for characteristic is trait. _____17. Genes control the expression of traits. _____18. An allele is an alternate form of a gene (Gene = eye color, allele = blue, brown, green, etc.) _____19. Purebred organisms are those that produce offspring with the same form of the trait (purebred plant with red flowers will always have offspring with red flowers). _____20. Traits are controlled by the alleles (two alleles) it inherits from its parents. _____21. Mendel discovered the dominant/recessive inheritance pattern after performing many crosses of garden peas. _____22. Some alleles are dominant, some are recessive, and some have other inheritance patterns. _____23. A dominant allele is one whose trait always expressed in the organism when the allele is present. _____24. A recessive allele is hidden whenever a dominant allele is present; the only time a recessive allele is expressed is when there are two recessive alleles alone. _____25. Scientists use symbols to represent the different alleles for a trait (T = tall is dominant, t = short is recessive). _____26. Traditionally, the letter of the dominant trait is used to create the symbol for the allele (except in the case of genetic disease, in which case the first letter of the disease is used – example cystic fibrosis is a recessive disease, but C = indicates the normal phenotype, and c = cystic fibrosis) _____27. Genotype is the allele combination for that trait found in the organism (TT, Tt, tt) _____28. Phenotype is the expression of the genotype (TT and Tt are tall, and tt is short) _____29. Hybrid indicates an organism with two different alleles (Rr, Ss, Tt) _____30. Homozygous individuals have two of the same alleles (TT or tt). _____31. Heterozygous individuals are also known as hybrids, and contain one of each allele (Tt or Rr). _____32. A Punnett Square is a simple diagram that is used to predict the possible combinations of alleles in offspring that result from a specific _____33. Selective breeding, cloning and genetic engineering are three methods for developing organisms with desirable traits. _____34. Example of applied genetics is DNA fingerprinting and the Human Genome Project By the conclusion of this unit, you should be able to do _____1. Explain the function of DNA and its role in the reproduction of organisms.. _____2. Calculate the probability of genetic crosses and explain their results. _____3. Predict the possible results of genetic crosses by modeling the combination of alleles in a genetic cross. _____4. Interpret data from models of genetic crosses (from item #2 above) to express what is actually meant by the phrases ‘dominance in a species’, ‘recessive in a species’, AND ‘other inheritance patterns in a species’. _____5. Distinguish between a ‘purebred’ organism and one that is not a ‘purebred’ organism. _____6. Understand why the work of Gregor Mendel was important to modern-day genetics. _____7. Identify two major causes of mutations in humans. _____8. Explain how geneticists trace the inheritance of traits. _____9. Describe how genetic disorders are diagnosed and treated. _____10. Compare and contrast the genetic technologies