EIT Health KIC Munich Innovation Roadshow 8th-9th May 2015 Requests and Offers for Collaboration 1. Organisation: Air Liquide/ Industry Partner/ Paris, France Contacts: Christopher Cala and Marc Lemaire Areas of interest: Digital Health Solutions in Multi-Morbidity Management and Prevention Requests and Offers: Collaborations on the development of connected devices to improve the exchange of data and thus the interoperability of software and hardware. Would like to work with public institutions, especially NHS trusts and CCGs, on the use and commissioning of interoperable innovation platforms and devices. Would also like to collaborate with cohorts of SMEs. Working particularly on: drug delivery; diagnostics; medical devices; nutrition; data analytics, fusion and clinical usage. Existing expertise in: Metabolics, COPD, diabetes, Parkinson’s, medical devices in the home, data fusion. 2. Organisation: Nofer Institute/ Applied Research/ Lodz, Poland Contact: Mikolaj Gurda Areas of Interest: Occupation Medicine Requests and Offers: Collaborations request to address poor health relating to indices of multiple deprivation, particularly social, cultural and economic. Currently working on health inequalities. Would like to know more about the living labs in the West Midlands, especially those where the above issues are prevalent. Looking at older people’s as well as the whole-life cycle health, particularly relating to the adult age population. 1 3. Organisation: University of Barcelona/ University/ Spain Contact: Montse(rrat) Cruz Areas of Interest: Community-based integrated care; wellness and prehabilitation using ICT; visual life-logging with digital innovations. Requests and Offers: UoB would like to explore the above areas in relation to: cancer, telemedicine, rare anaemias, biomarkers and nutrition, with companies and NHS departments with these specialisms. 4. Organisation: Frauenhofer Instituet/ Applied Research/ Erlangen, Germany Contact: Thomas Norgall Areas of interest: Ambient assisted living. Particular request for clinical biomechanics collaborations. Requests and Offers: Request for collaborations in monitoring and analysis of gait and motion for stroke rehabilitation. Would particularly like industry collaborations. 5. Organisation: Stockholm City Council/ Local Authority/ Sweden Contacts: Maria Soederlund (Healthcare) and Carl Smitterberg (Health and Social Care) Areas of Interest: Healthcare and health and social care public services provision. Requests and Offers: Seeking better collaborations with industry partners in developing solutions to aid health and health and social care delivery. Areas of particular interest include: whole-life informatics, preventative health solutions, care transitions between primary and acute settings, and the standardization and flexibility of solutions for care (especially with reference to digital and systemic interoperability). 2 6. Organisation: Stockholm City Council/ Local government/ Sweden Contact: Marina Taloyan Areas of Interest: Preventative health solutions throughout the health and social care, and primary and acute care pathways, i.e. integrated care. Registers and big data. Requests and Offers: Digital solutions to improving integrated care pathways. Collaborations on integrated care protocols and business models. 7. Organisation: Karolinska Institutet/ Applied Research/ Stockholm, Sweden Contact: Kristina Johnell Areas of Interest: Quality and safety in drug use in order to help people through patient- centred ICT solutions. Requests and Offers: Drug delivery optimization. KI has already developed a product which has reached the Swedish market. The product helps physicians to prescribe the correct combination of drugs for patients with multi-morbidities, minimizing effectiveness and minimizing side-effects and counteraction. The institute is looking to partner healthcare providers and public healthcare testbeds in other countries to fine-tune their product and make it available to other markets. 8. Organisation: The Institute of Biomechanics, Valencia/ Applied Research/ Spain Contact: Javier Ferris Areas of Interest: Digital health and engineering, particularly in therapeutics, occupational health, co-creation tools and online platforms. Requests and Offers: IBV has several project offerings on the table, at present: Simplit- Co-creation tool for businesses and service users. This is a digital tool that integrates researcher expertise from the institute. IBV would like to adapt it to help patients in different countries and of diverse demographics. Man-Made- This has grown out of a FP7 project. The initiative focuses on occupational health and adapting the workplace to integrate complementary 3 leisure, nutritional and exercise-based activities. This is not designed for a particular age-group or demographic in mind, but IBV would like to explore how it could be used in preventative health solutions and applied to the older workforce/ silver economy. Intelligent Motion Analysis- This project comprises therapies for musculoskeletal conditions. It is essentially an ICT tool to measure conditions and recommend treatments. IBV would like to partner hospitals to trial and test it, especially in rehabilitation departments. Online Platform for Medical Implants PersonalisationSleep Screenings. Measuring sleep and prescribing sleep solutions, including solutions for dementia and sleep apnea. (See further information from Javier Ferris, attached.) 9. Organisation: Siemens/ Industry/ Erlangen, Germany Contact: Leandro Burns Areas of Interest: Open innovation in healthcare. Entrepreneurial spirit programme for healthcare. Requests and Offers: Siemens would like a co-creational education programme linking industry to public services and end-users. They are mostly interested in the connected health economy and the living labs of the West Midlands, as well as the health and entrepreneurship ideas being developed at universities within the region who have already put forward projects in the education project EOI round. 10. Organisation: Sanofi/ Industry. Paris, France Contact: Jean-Marc Bourez Areas of Interest: e-Health and Big Data. Current Big Data activity is particularly around oncology, diabetes and corporate wellness. Requests and Offers: Sanofi is currently conducting work on research and clinical applications in the use of base data, data-visualisation and biomarkers. It has a great deal of expertise in e-health and tools, sensors and mobile health. It seeks collaborative partners with hospitals, research institutes and clinical study units, in particular, academic-based partnerships. Sanofi would be a very good partner to collaborate with on illness prevention and reduction in relation to occupational health and issues around behaviour change and metabolics, stress, sleep, smoking, quality of life in the workplace and nutrition. 4 11. Organisation: The University of Copenhagen/ Denmark Contact: Suresh Kumar Areas of Interest: Health and business education collaborations with other universities and industry. (Need further information from SK) 12. Organisation: ATOS/ Industry/ Madrid, Spain Contact: Pedro Soria-Rodriguez Areas of Interest: Cybersecurity and electronic identity Requests and Offers: Collaboration on the development of security techniques and solutions applied to various healthcare sectors. Current areas of expertise include: data analytics; the internet of things; sensor networks; systems security; data security; metadata; privacy protection for personal data; patient health records; interchange of data between hospitals; and secure device to device communication. ATOS is interested in possible collaborations between primary and acute care organisations, and developing relationships with the cybersecurity clusters in the West Midlands. 13. Organisation: RISE/ Industry/ Sweden Contact: Albin Andersson Areas of Interest: Patient- centred service innovation. Requests and Offers: RISE is interested in developing healthy ageing responses and solutions that equalise the relationships between patients and clinicians through the cocreation of healthy living approaches. It is particularly interested in the WM region’s living labs for future work around Type 2 diabetes and other long-term conditions. It would also like to explore the ‘public procurement of health innovations’ space, to understand where and how co-creation could influence the purchase of better and more appropriate patient care solutions. 5 14. Organisation: Nuffield Health/ Industry/ Oxford, England Contact: Ben Kelly Areas of Interest: Digital health and, in particular, data, long-term conditions management, exercise management and monitoring, and the employment of health psychology solutions. Requests and Offers: Nuffield is interested in health, nutrition, exercise and wellness, and particularly the whole-life and holistic approach to keeping active and well. It is also interested in issue of patient safety and the physical and psychological aspects of this. Ben expressed interest in our the living labs and patient safety collaborative work. 15. Organisation: University of Evora/ Portugal Contact: David Mendes Areas of Interest: Smart health and smart living environments; interoperability of software and hardware; the internet of things; computational linguistics and semantics relating to communicating across languages and cultures; and artificial intelligence. Requests and Offers: The University of Evora is currently engaged with IBM in developing technologies that help to direct patients/ service-users and their carers to managing the former’s community, primary and acute care needs. Those with health needs and those look after them are able to communicate despite different languages and cultural norms, and carers are also able to take the right actions when health problems are detected by them or by the bespoke AI set-up of the patient. Evora and IBM are developing a health-based Watson (IBM’s super computer system) and would like to partner living labs/ communities, health and social care organisations, and primary and acute trusts, in the UK to develop solutions for particular UK communities. 16. Organisation: Erasmus MC/ University/ Rotterdam, Netherlands Contact: Menno Kok Areas of Interest: Better healthier and longer living before conception. 6 Requests and Offers: Erasmus Medical Centre is offering collaborations to other European countries to trial, test and implement a lifestyle programme for people who are planning to have children. The programme has achieved clinical success in the birth of healthy babies and a rise in successful IVF treatments. EMC is looking to partner hospitals, clinics and universities to address the clinical guidelines, procurement and socio-cultural issues around the programme and how it may be implemented successfully in the UK. 17. Organisation: University of Aberystwyth/ Wales Contact: John Draper and Marco Arkesteijn Areas of Interest: Nutrition and exercise for healthy living and healthy ageing. Requests and Offers: Prof. John Draper has forwarded the following information and is happy for WMAHSN members to use it. However, he asks that it be kept confidential beyond the immediate network and, thus, it cannot be used for wider circulation at this time. Aberystwyth is a leading international specialist in nutritional sciences and would like to work with test beds to assess the utility and health care community interest in: (1) Integration of urine biomarkers in stratification of vulnerable individuals (a) A test of personal 'metabotype' to determine an individuals' metabolic phenotype and particularly how their endogenous metabolism and their gut microbiome interact with key dietary components, dietary supplements and prescribed pharmaceuticals. (b) A test of dietary exposure, using biomarkers to assess the healthiness of diet or even malnutrition in vulnerable individuals. Metabolic phenotype alters with age as diet and behaviours change, but understanding how far down in the aging trajectory an individual has progressed is difficult. The first of these tests would be aimed at stratifying, particularly vulnerable members, of a population to allow more precise recommendations with regard to overall nutrition and medication. The second test would help to develop a personalised diet for particularly vulnerable individuals being looked after by different health care organisations, or nursing homes or supported at home by community services. 7 For both of these projects there is interest from other CLCs (Spain, France, Benelux and Scandinavia) as well as InnoStars but having a UK activity is highly desirable. A key aspect of the strategy is to build on the progress Aber has made in current MRC Programme Grant in obtaining informative spot urines from home environment; these methods offer scope to bring biomarker technology into the community-based health decision making. There is additional interest in developing SMEs to carry out such diagnostic services. (2) Development of a pan-EU ‘pipeline’ to validate efficacy of functional foods to support an aging populations Diet has a major impact on wellbeing, apart from simply providing nutrients. Aber has several partners in place and emerging support from the Welsh government to integrate functional foods containing established bioactives into the diet of individuals at risk of, or, in early stages of developing CHCs. With a large investment in Analytical Chemistry Technology (> £10 M) , a £4 M Biorefining Centre and a £5 M Future Food Centre in Aberystwyth Innovation and Enterprise Campus the university is developing an SME network dedicated to ‘fortifying’ initially oat food products (e.g. smoothies, porridge and oat bars) with plant concentrates or extracts containing combinations of natural compounds that have already been show in structured clinical trials to impact for example on Alzheimer’s, T2DM, CVD, IBS and satiety. [ This project would interact with the dietary exposure and metabotyping projects mentioned above] What would be of particular interest are interactions with partners, such as WMAHSN members, able to validate in pilot studies the impact of these new foods on wellbeing and CHC progression/amelioration in a real community setting with established cohorts of potentially vulnerable individuals. We would wish to be able to measure functional food impact on for example cognitive, metabolic, cardiovascular and alimentary wellbeing characteristics. In the longer term we need to have healthcare economists able to project the impact (financial and stress on NHS and Social Services) of any validated dietary intervention on maintaining individuals able to live independently for longer in their own home or to have reduced needs if in long term care. There is a particular interest also in developing a dialogue with government authorities involve in legislation surrounding food labelling to create a much larger market for functional foods ‘winning’ a health promoting label. One project concept is a demonstration project involving several CLCs across the EU to develop the SOPs for functional food testing and approval. Apart from food products and markets for functional foods, a key output would be the development of new working practices within community health care systems. 8